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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
201

Regulation and function of Skp2 in mediating p27 degradation during adipocyte hyperplasia

Auld, Corinth Andrews. January 1900 (has links) (PDF)
Thesis (Ph. D.)--University of North Carolina at Greensboro, 2006. / Title from PDF title page screen. Advisor: Ron Morrison; submitted to the School of Human Environmental Sciences. Includes bibliographical references.
202

Mechanisms by which conjugated linoleic acid causes human adipocyte delipidation

Chung, Soonkyu. January 1900 (has links) (PDF)
Thesis (Ph. D.)--University of North Carolina at Greensboro, 2006. / Title from PDF title page screen. Advisor: Michael K. McIntosh; submitted to the School of Health and Human Performance. Includes bibliographical references (p. 133-151).
203

Sexual dimorphism of the fat-derived anti-diabetic hormone adiponectin

Chan, Kok-weng. January 2005 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2005. / Title proper from title frame. Also available in printed format.
204

The effects of a pre-exercise meal and supplement on trained athletes

Miller, Meredith Renee. January 2002 (has links)
Thesis (M.A.)--San Francisco State University, 2002. / Includes bibliographical references (leaves 19-23).
205

The effects of a pre-exercise meal and supplement on trained athletes

Hagobian, Todd Alan. January 2002 (has links)
Thesis (M.A.)--San Francisco State University, 2002. / Includes bibliographical references (leaves 36-40).
206

The feeding and fat dynamics of resident juvenile Atlantic salmon (Salmo salar L.) during winter

Bull, Colin D. January 1996 (has links)
This thesis investigated the relationships between the feeding behaviour and use of stored fat in overwintering Atlantic salmon parr remaining destined to remain resident in freshwater the following year. Experiments investigated the responses to periods of food shortage at different times of the year to assess the influence of season. Investigations were carried out to examine how feeding motivation and fat storage were influenced by changes in those environmental cues that indicate the change of season. The effect of the normal winter behavioural pattern upon feeding and fat was also investigated.
207

The measurement of physical activity in children

Rowlands, Ann V. January 1998 (has links)
This thesis includes one qualitative literature review, three empirical studies and one meta-analysis examining the measurement of physical activity in children. Previous research has highlighted the difficulties inherent in measuring children's habitual activity. This has lead to confusion regarding the relationships between physical activity and health in children. Recently a new type of activity monitor has been developed. Uniaxial (WAM, Computer Science Applications, Shalimar, Florida, USA) and triaxial (Tritrac, Professional Products, a division of Reining International, Madison, WI, USA) accelerometers that record temporal, frequency and intensity information of movement are now commercially available. The aims of this thesis were to evaluate the validity of these and other measures of physical activity in children, to examine the relationship between physical activity and body fat in children and to investigate the effect the mode of activity measurement has on this relationship. The main findings were: a) The Tritrac provided a significantly better estimate of scaled oxygen consumption during typical children's activities than the WAM, heart rate or pedometry; b) Physical activity, measured by the Tritrac or the pedometer, was inversely correlated with body fat and positively correlated with aerobic fitness; c) Heart rate measures of physical activity did not correlate significantly with body fat or aerobic fitness; d) Meta-analytic procedures showed a small to moderate relationship between activity levels and body fat in children; e) The strength of this relationship was heavily dependent on the method used to assess activity levels. Observation methods produced an effect size significantly higher than questionnaire or heart rate methods, though not significantly different to motion counter methods. In conclusion it appears that heart rate methods are inappropriate for the assessment of habitual activity in children. The use of motion counters or observation methods for assessing activity are recommended. Motion counter methods are particularly appropriate for medium to large sample sizes.
208

Análise in vivo da relação entre hipóxia e estresse oxidativo sobre o desenvolvimente embriofetal do pâncreas de descendentes de ratas diabéticas

Iessi, Isabela Lovizutto [UNESP] 26 February 2015 (has links) (PDF)
Made available in DSpace on 2016-08-12T18:48:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-02-26. Added 1 bitstream(s) on 2016-08-12T18:50:54Z : No. of bitstreams: 1 000865249_20170310.pdf: 411293 bytes, checksum: f8c1d02bfb772bbd81e4a7df20358928 (MD5) Bitstreams deleted on 2017-03-10T13:07:29Z: 000865249_20170310.pdf,. Added 1 bitstream(s) on 2017-03-10T13:08:14Z : No. of bitstreams: 1 000865249.pdf: 1415116 bytes, checksum: f43ae6a121d2b64591e3365fbace0d36 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / Durante a gravidez diabética, a hiperglicemia materna pode prejudicar o desenvolvimento embrionário por uma associação de hipóxia e estresse oxidativo. Deste modo, nossa hipótese é de que a combinação desses mecanismos esteja envolvida no desenvolvimento pancreático alterado. Portanto, o objetivo do presente estudo foi avaliar os efeitos do estresse oxidativo e hipóxia no organismo materno sobre o desenvolvimento pancreático fetal em condições hiperglicêmicas. Foram utilizados ratos da linhagem Wistar que foram aleatoriamente distribuídos em: Controle (C); Diabete moderado (DM) e Diabete grave (DG). O diabete foi induzido em ratos pela administração de streptozotocin. As ratas foram acasaladas e, no 18º e 21º dias de prenhez, foram avaliados parâmetros como hiperglicemia e marcadores de hipóxia e de estresse oxidativo maternos. Nos mesmos momentos, os fetos foram coletados para análise das ilhotas pancreáticas. Foram encontradas alterações na tríade hormonal (insulina, glucagon e somatostatina) e marcadores de proliferação celular (PDX-1 e ki67) e morte celular (caspase-3). Essas alterações foram mais evidentes nos fetos advindos do grupo diabete grave. Além disso, a morfologia das ilhotas pancreáticas fetais e localização correta das células endócrinas foram claramente alteradas. Também houve correlação positiva entre glicemia, estresse oxidativo e hipóxia no organismo materno dos grupos diabéticos. Estes mecanismos também foram positivamente correlacionados com a redução no número de ilhotas e de células por ilhota nos descendentes. Portanto, a presença de estresse oxidativo e hipóxia, induzidos por alterações glicêmicas maternas, causou prejuízo no desenvolvimento pancreático fetal. Este fato demonstra que é necessário um rígido controle glicêmico materno para prevenir complicações embriofetais e perinatais / In diabetic pregnancy, hyperglycemia may impair embryonic development by a combination of hypoxia and oxidative stress. Therefore, we hypothesized that a combination of these factors was involved in the impaired pancreatic development in the offspring. Thus, the objective of the present study was to evaluate maternal oxidative stress and hypoxia status on fetal pancreatic development in hyperglycemic conditions. Wistar rats were randomly assigned into three groups: control (C); mild diabetes (MD) and severe diabetes (SD). Diabetes was induced by the beta-cytotoxic drug (streptozotocin) in rats. The female rats were mated and at days 18 (early period of maximum fetal development) and 21 (at term) of pregnancy the maternal hyperglycemia, hypoxia and oxidative stress markers were evaluated. In the fetus, the pancreatic islets were analyzed. The results showed alterations in pancreatic hormone triad (insulin, glucagon and somatostatin), beta cell marker (PDX-1), proliferation (ki67) and apoptosis (caspase-3), which were more pronounced in the SD group. Furthermore, the morphology of the fetal pancreatic islets was clearly changed. There was a positive correlation between blood glucose, oxidative stress and hypoxia of the mothers and the reduction in the number of islets and number of cells per islet in the fetuses from the diabetic groups. Therefore, oxidative stress and hypoxia induced by maternal hyperglycemia led to impairment of fetal pancreatic development. These observations indicate that a rigid glycemic control in diabetic pregnancy is required to prevent the embryofetal and perinatal complications / FAPESP: 11/23642-2
209

CONSELHOS de Administração: uma Análise das Suas Características e Impacto Sobre As Firmas no Mercado Acionário Brasileiro

BRUGNI, T. V. 04 September 2012 (has links)
Made available in DSpace on 2016-08-29T11:13:25Z (GMT). No. of bitstreams: 1 tese_5451_.pdf: 708934 bytes, checksum: 1c020dba02ac9a481d989c760a2f5646 (MD5) Previous issue date: 2012-09-04 / O presente trabalho teve por objetivo identificar quais os principais atributos que caracterizam conselhos de administração no Brasil, permitindo assim uma melhor compreensão das suas influências no mercado de capitais. Identificou-se que existe um alto grau de correlação entre as 31 características analisadas, sugerindo que outras pesquisas sobre o tema podem ter evidenciado relações de certas variáveis que possivelmente estavam refletindo boa parte de outras características fortemente correlacionadas. Buscou-se, pois, compreender melhor o ambiente no qual se encontram os conselhos de administração para então definir, de fato, quais são suas principais características sob a ótica da variância de um conjunto maior de variáveis. A Análise Fatorial (AF) permitiu uma análise mais aprofundada das características sobre essa vertente, expurgando as correlações específicas entre elas e construindo fatores não correlacionados. A partir desse cenário, cinco índices foram construídos para refletir os fatores extraídos da AF, permitindo que estes fossem relacionados com o valor e desempenho das firmas por intermédio de regressões múltiplas, a citar: Remuneração variável, fixa, dedicação do membro ao conselho, formação básica do conselheiro e grau de instrução stricto sensu (mestrado e doutorado). Os resultados foram divididos em três seções: i) caracterização dos conselhos de administração no Brasil, para permitir uma melhor compreensão desse ambiente empresarial no país; ii) determinação das principais características desses conselhos, ou seja, quais características que mais explicam a variância dos dados, por intermédio da Análise Fatorial e; iii) relação entre os índices construídos com o retorno, retorno anormal, Q de Tobin, ROA e ROE, no sentido de verificar se as características que sintetizam o ambiente dos conselhos são enxergadas pelos investidores como importantes no momento do investimento. Os achados indicam que a remuneração dos conselheiros é responsável por explicar cerca de 40% da variância dos dados referentes aos conselhos, sugerindo que essa característica é de grande importância no espectro da governança corporativa, especialmente no que tange os conselhos de administração das empresas. Identificou-se também que o fator remuneração fixa influencia de forma negativa e significante no retorno anormal e no Q de Tobin. A relação entre os outros fatores e as variáveis dependentes também foram testadas e os resultados sugerem que a dedicação dos membros ao conselho é significante para explicar o Q de Tobin e o nível de instrução dos membros explicam significantemente o retorno, o retorno anormal e o Q de Tobin.
210

Influence of the type of carbohydrate breakfasts on metabolism and endurance running capacity in man

Wee, Shiou-Liang January 1999 (has links)
Compared to the overnight fasted state, a high carbohydrate (CHO) breakfast 3-4 hours before exercise enhances endurance performance. However, the optimal type or composition of the pre-exercise meal to be consumed is less clear. Glycaemic and insulinaemic responses to a meal play a key role in subsequent metabolism during exercise. The investigations described in this thesis focused on the influence of I) the composition and 2) glycaemic index (GI) of CHO breakfasts 3 hours before exercise on postprandial and exercise metabolism and endurance running capacity.

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