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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Exon/Intron Discrimination Using the Finite Induction Pattern Matching Technique

Taylor, Pamela A., 1941- 12 1900 (has links)
DNA sequence analysis involves precise discrimination of two of the sequence's most important components: exons and introns. Exons encode the proteins that are responsible for almost all the functions in a living organism. Introns interrupt the sequence coding for a protein and must be removed from primary RNA transcripts before translation to protein can occur. A pattern recognition technique called Finite Induction (FI) is utilized to study the language of exons and introns. FI is especially suited for analyzing and classifying large amounts of data representing sequences of interest. It requires no biological information and employs no statistical functions. Finite Induction is applied to the exon and intron components of DNA by building a collection of rules based upon what it finds in the sequences it examines. It then attempts to match the known rule patterns with new rules formed as a result of analyzing a new sequence. A high number of matches predict a probable close relationship between the two sequences; a low number of matches signifies a large amount of difference between the two. This research demonstrates FI to be a viable tool for measurement when known patterns are available for the formation of rule sets.

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