Thesis (M.A.)--York University, 2008. Graduate Programme in Psychology. / Typescript. Includes bibliographical references (leaves 58-63). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR45956

Thesis (Ph. D.)--York University, 1999. Graduate Programme in Psychology. / Typescript. Includes bibliographical references (leaves 168-189). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pNQ39287.

Focused ultrasound therapy can be enhanced with microbubbles by thermal and cavitation effects. However, localization of treatment becomes difficult as bioeffects can occur outside of the target region. Spatial control of gas bubbles can be achieved with acoustic vaporization of perfluorocarbon droplets. This study was undertaken to determine the acoustic parameters for bubble production by droplet vaporization and how it depends on the acoustic conditions and droplet physical parameters. Droplets of varying sizes were sonicated in vitro with a focused ultrasound transducer and varying frequency and exposure. Simultaneous measurements of the vaporization and inertial cavitation thresholds were performed. The results show that droplets cannot be vaporized at low frequency without inertial cavitation occurring. However, the vaporization threshold decreased with increasing frequency, exposure and droplet size. In summary, we have demonstrated that droplet vaporization is feasible for clinically-relevant sized droplets and acoustic exposures.

Using counselling sessions conducted by ten "master therapists" (e.g., Rogers, Ellis, Perls) from four different schools of psychotherapy, the present study investigated relationships between four variables: Client experiencing, emotional arousal/expression, productive client in-session behaviours, and therapist interventions. / High levels of client experiencing occurred in significantly different proportions across schools in the sample, and had significantly different interactions with clients' productive in-session behaviours across the four schools studied. Likewise, admixtures of client experiencing and strong emotional arousal occurred to significantly different proportions across schools, and these admixtures also had significantly different interactions with clients' productive in-session behaviours across the four schools. These findings demonstrate that clients' productive in-session behaviours are not uniformly facilitated by high levels of experiencing across all schools. / Next, across schools, therapist interventions of low structure were found to be significantly more associated with subsequent high levels of client experiencing than were interventions of moderate or high structure. However, loglinear analysis indicated that this association varied across schools, suggesting that the same therapist interventions had different in-session outcomes in different schools. The same three interventions were most likely to be followed by high experiencing in all schools: Reflection, interpretation, and provision of information. The common factors implications of this finding are discussed. / Finally, in order to take in-session context into account, a second study examined in-session episodes that represented different experiencing/emotional arousal conditions. Two clinically experienced judges rated 23 aspects of the in-session process (i.e., therapist tasks, client tasks, client focus, and quality of episodes) of 24 such different episodes. Only one aspect emerged as significant: When working with clients at high levels of Experiencing, but without strong emotional arousal levels, therapists were significantly more likely to identify clients' underlying affect than in the other two Experiencing/emotional arousal episode types. No other significant differences were found in the therapist or clients' tasks, client focus, or quality of the different episodes. Several methodological directives are offered for future researchers employing a design similar to that of this second study.

Focused ultrasound therapy can be enhanced with microbubbles by thermal and cavitation effects. However, localization of treatment becomes difficult as bioeffects can occur outside of the target region. Spatial control of gas bubbles can be achieved with acoustic vaporization of perfluorocarbon droplets. This study was undertaken to determine the acoustic parameters for bubble production by droplet vaporization and how it depends on the acoustic conditions and droplet physical parameters. Droplets of varying sizes were sonicated in vitro with a focused ultrasound transducer and varying frequency and exposure. Simultaneous measurements of the vaporization and inertial cavitation thresholds were performed. The results show that droplets cannot be vaporized at low frequency without inertial cavitation occurring. However, the vaporization threshold decreased with increasing frequency, exposure and droplet size. In summary, we have demonstrated that droplet vaporization is feasible for clinically-relevant sized droplets and acoustic exposures.

Thesis (M.A.). / Written for the Dept. of Educational and Counselling Psychology. Title from title page of PDF (viewed 2009/06/12). Includes bibliographical references.

Thesis (M. Sc.)--University of Alberta, 2010. / Title from pdf file main screen (viewed on June 24, 2010). A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Master of Science in Physics, Department of Physics, University of Alberta. Includes bibliographical references.

acase@tulane.edu / Cancer’s response to mechanical vibration via high-intensity focused ultrasound and disruptive chemical agents (Mechanochemical Disruption) was examined in vitro and in vivo. We demonstrated that mechanochemical disruption of cellular structures induced phenotypic alterations in surviving tumor cells that prevented cancer progression. Mechanochemical disruption inhibited uncontrolled proliferation, tumorigenicity, metastatic development, and re-sensitized multiple cancer types to chemical treatment via alterations in protein expression and impediment of pro-survival signaling. Our study identified a novel curative therapeutic approach that can prevent the development of aggressive cancer phenotypes. / 1 / hakm murad

In recent years, there has been an increasing interest in the study of hydrophobic surfaces. Hydrophobic surfaces have been used in multiple applications in microfluidic devices due to their properties of self-cleaning, and also in deicing products. Conventionally, hydrophobic surfaces were created by laser cutting, self-assembly and other chemical processing methods. However, in most of these methods, hydrophobicity of the surface cannot be maintained for an extended time or restricted to limited set of materials. A low-cost, high-throughput method to generate highly hydrophobic anisotropic surface has been developed in this thesis which uses Computer Numerical Control (CNC) machining employing diamond tools whose tips have been micro-structured using Focused Ion Beam (FIB) built tips. The versatility of this method has been demonstrated by machining both metal and polymeric materials. Significant anisotropic wetting has been observed on the machined surface with the anisotropic contact angle can reach up to 71.6 degree and highly-hydrophobic property with contact angle of 163.1degree on 6061 Aluminum Alloy and 155.7 degree on PMMA surface. / Thesis / Master of Science in Mechanical Engineering (MSME)

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