Landfilling is the most common approach to dispose of municipal solid wastes but inevitably leads to leachate formation. Persistent UV quenching substances (UVQS) in landfill leachate can affect the effectiveness of UV disinfection in municipal wastewater treatment systems when leachate co-treatment is applied. Membrane electrochemical reactor (MER) treatment was investigated to reduce the UV quenching capability and simultaneously recover resources in the leachate as an effective onsite pre-treatment. Ion-selective membranes were used in this MER to create two different conditions: a low-pH anolyte for organic oxidation and a high-pH catholyte for ammonia recovery. The MER achieved significantly higher removals of both dissolved organic carbon and UV254nm absorbance than membrane-less electrochemical treatment. The MER was able to remove a large percentage of total nitrogen from the leachate while recovering about half of the influent ammonia in the catholyte with less specific energy consumption. The second study coupled MER with Fenton oxidation through providing synergistic benefits with the low solution pH, reduced organics, and ammonia removal. This two-stage coupled system reduced the more leachate COD than the standalone Fenton process treating raw leachate. Also, the usage of chemicals as Fenton reagents has been greatly reduced: FeSO4 and H2O2 by 39%, H2SO4 by 100%, and NaOH by 55%. Consequently, the sludge production was reduced by 51% in weight and 12% in volume. Despite electricity consumption by the MER, the coupled system cost $4.76 per m3 leachate less than the standalone Fenton treatment. More notably, direct Fenton oxidation removed only 21% of ammonia; in comparison, the MER-Fenton system removed ammonia by 98% with the possibility for recovery at a rate of 30.6 -55.2 kg N m-3 reactor d-1. Those results demonstrated that coupling MER with the Fenton process could mitigate some inherent drawbacks of Fenton oxidation such as ineffective ammonia removal, high acid and chemical reagents dose requirements, and a large amount of sludge generation. The third study investigated the formation of total halogenated organics (DBP) and the associated toxicity as the side effect of leachate treatment in the MER. Compared to the 4538±100 µg L-1 from the control membrane-less electrochemical oxidation reactor, the amount of DBP generated in the MER only accounted for 19.1±4.5 % after the same treatment period. The total toxicity value (26.6 ×10-3 ) was low for MER effluent, only 15.1% of that in the control group. Both high pH and high ammonia concentration introduced more DBP mass and toxicity production after MER treatment. DBP concentrations were shown to increase with applied current density and possible temperature raise. With 67.5% of DBP mass concentration and 74.4% of the additive toxicity removal, the granular activated carbon (GAC) electrode system was shown more effective than GAC adsorption alone in remediating DBP harmful effects. This dissertation introduced MER as a promising technology for the treatment of leachate through performance demonstration, process integration and by-product remediation. / Doctor of Philosophy / Municipal solid waste is often disposed of in landfills because of the most economics and convenience. However, one of the most challenging problems is the leachate formation and treatment. In the US, leachate is currently often diluted in domestic wastewater treatment systems; meanwhile, the persistent contaminants in landfill leachate can lower the effectiveness of UV disinfection and result in high cost and permit violation. In this study, the membrane electrochemical reactor (MER) using electricity as the driving force was applied to solve the issue and simultaneously recover valuable resources in the leachate. Membranes as a barrier for selective ions were used in this MER to create two different conditions with different purposes: a low-pH anolyte for organic oxidation and a high-pH catholyte for ammonia recovery. The MER achieved significantly higher contaminants removals than membrane-less electrochemical treatment. The second study coupled MER with one of the established advanced oxidation processes, also known as Fenton oxidation through providing mutual benefits with the low solution pH, reduced organics, and ammonia removal/recovery. This two-stage coupled system reduced the leachate contaminants effectively towards the direct discharge standard. In addition, the usage of chemical reagents, as well as the amount of process residual, has significantly been reduced. The third study investigated the formation of by-products as the side effect of leachate treatment in the MER. Compared to the membrane-less reactor, the undesirable by-products generated in the MER only accounted for one fifth after the same treatment period. A granular activated carbon electrode system was shown effective in remediating the harmful effects. This dissertation introduced MER as a promising technology for the treatment of leachate as one of the toughest wastewaters.