Global ETD Search

11	Studies on global regulators involved in virulence gene expression in Staphylococcus aureus / Kanth, Anna, January 2003 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 4 uppsatser.
12	Bacterial gene expression inhibition with antisense peptide nucleic acids / Dryselius, Rikard, January 2005 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 5 uppsatser.
13	The PhoPQ two-component regulatory system : at the crossroads of nitrosative stress and Salmonella pathogenesis / Bourret, Travis John. January 2008 (has links) Thesis (Ph.D. in Microbiology) -- University of Colorado Denver, 2008. / Typescript. Includes bibliographical references (leaves 112-132). Free to UCD Anschutz Medical Campus. Online version available via ProQuest Digital Dissertations;
14	Structural basis for transcription regulations in Mycobacterium tuberculosis by iron-dependent regulator and dormancy survival regulator / Wisedchaisri, Goragot. January 2005 (has links) Thesis (Ph. D.)--University of Washington, 2005. / Vita. Includes bibliographical references (leaves 232-250).
15	Genetic adaptation of Salmonella enterica to phagocytic cells / Eriksson, Sofia, January 2003 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 4 uppsatser.
16	New insights into the role of ppGpp and DksA through their effect on transcriptional regulation of housekeeping and colonization related genes of Escherichia coli / Åberg, Anna, January 2008 (has links) Diss. (sammanfattning) Umeå : Univ., 2008. / Härtill 3 uppsatser.
17	Bacterial virulence and adaptation mediated by two-component system signalling / Tomenius, Henrik, January 2006 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 5 uppsatser.
18	Lactobacilli expressing antibody fragments against pathogens / Hultberg, Anna, January 2006 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 4 uppsatser.
19	Epigenetic regulation of the nitrosative stress response and intracellular macrophage survival by extraintestinal pathogenic Escherichia coli. Bateman, SL, Seed, PC 03 1900 (has links) Extraintestinal pathogenic Escherichia coli (ExPEC) reside in the enteric tract as a commensal reservoir, but can transition to a pathogenic state by invading normally sterile niches, establishing infection and disseminating to invasive sites like the bloodstream. Macrophages are required for ExPEC dissemination, suggesting the pathogen has developed mechanisms to persist within professional phagocytes. Here, we report that FimX, an ExPEC-associated DNA invertase that regulates the major virulence factor type 1 pili (T1P), is also an epigenetic regulator of a LuxR-like response regulator HyxR. FimX regulated hyxR expression through bidirectional phase inversion of its promoter region at sites different from the type 1 pili promoter and independent of integration host factor (IHF). In vitro, transition from high to low HyxR expression produced enhanced tolerance of reactive nitrogen intermediates (RNIs), primarily through de-repression of hmpA, encoding a nitric oxide-detoxifying flavohaemoglobin. However, in the macrophage, HyxR produced large effects on intracellular survival in the presence and absence of RNI and independent of Hmp. Collectively, we have shown that the ability of ExPEC to survive in macrophages is contingent upon the proper transition from high to low HyxR expression through epigenetic regulatory control by FimX. / Dissertation Animals Cell Line DNA, Bacterial Epigenesis, Genetic Escherichia coli Escherichia coli Proteins Fimbriae Proteins Gene Expression Regulation, Bacterial Macrophages Mice Promoter Regions, Genetic Reactive Nitrogen Species Sequence Deletion Sequence Inversion Virulence Factors
20	Examination of Neisseria gonorrhoeae opacity protein expression during experimental murine genital tract infection / Simms, Amy Nicole. January 2005 (has links) (PDF) Thesis (Ph. D.)--Uniformed Services University of the Health Sciences, 2005. / Typescript (photocopy).

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