Global ETD Search

31	Medroxyprogesterone acetate : a dual function hormone that is both a progestin and an androgen in human breast cancer cells / Ghatge, Radhika P. January 2005 (has links) Thesis (Ph.D. in Molecular Biology) -- University of Colorado at Denver and Health Sciences Center, 2005. / Typescript. Includes bibliographical references (leaves 89-109 and 224-228).
32	Expression of the metastasis suppressor gene KISS1 in uveal and cutaneous melanoma Martins, Claudia Maria de Oliveira, 1961- January 2008 (has links) No description available. Uveal Neoplasms -- genetics. Skin Neoplasms -- genetics. Gene Expression Regulation, Neoplastic. Tumor Suppressor Proteins -- physiology. Melanoma -- genetics.
33	Molecular and functional characterization of a novel G-patch containing protein-IER3IP1. / CUHK electronic theses & dissertations collection January 2003 (has links) Yiu Wai Han. / "June 2003." / Thesis (Ph.D.)--Chinese University of Hong Kong, 2003. / Includes bibliographical references (p. 146-156) / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese. Carrier proteins--Molecular genetics Membrane proteins--Molecular genetics Genetic regulation Carrier Proteins--genetics Membrane Proteins--genetics Gene Expression Regulation, Neoplastic
34	Biological pathways in B-cell non-Hodgkin's lymphoma Aggarwal, Mohit, January 2009 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2009. / Härtill 4 uppsatser.
35	Differential regulation of c-Cbl and Cbl-b ubiquitin ligases downstream of the Met receptor tyrosine kinase Durrant, Michael, 1982- January 2007 (has links) The Cbl family of E3 ubiquitin ligases are important negative regulators of multiple receptor and cytoplasmic tyrosine kinases, and participate in a wide variety of cellular processes. Uncoupling of Cbl-mediated negative regulation allows activated receptor tyrosine kinases such as the Met receptor to escape degradation, enhancing their oncogenic potential in vitro and in vivo. Despite the consequences of loss of Cbl-mediated negative regulation for human disease, little is known about the mechanisms regulating Cbl protein levels themselves. / In this thesis work, I demonstrate a differential regulation of c-Cbl and Cbl-b downstream of the Met receptor tyrosine kinase. Cbl-b protein levels decrease in response to Met kinase activity, whereas c-Cbl levels remain stable. Cbl-b is partially degraded in a proteasome-dependant manner. This requires Cbl-b ubiquitin ligase activity and a carboxy terminal domain region located between the RING and UBA domains. I conclude that the regulation of c-Cbl and Cbl-b differs downstream of Met, and propose that negative regulation of Cbl-b by a dysregulated Met receptor may contribute to tumourigenesis. Gene Expression Regulation, Neoplastic. Ubiquitin-Protein Ligases -- metabolism.
36	Molecular alterations in colorectal cancer / Jansson, Agneta, January 2002 (has links) (PDF) Diss. (sammanfattning) Linköping : Univ., 2002. / Härtill 4 uppsatser.
37	Localization and characterization of genes involved in parathyroid tumor development / Forsberg, Lars, January 2003 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 5 uppsatser.
38	Differential RNA expression in benign and malignant adrenocortical tumours / Velázquez-Fernández, David. January 2005 (has links) Lic.-avh. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 2 uppsatser.
39	Novel extrahepatic P450 enzymes with emphasis on the tumor specific CYP2W1 / Karlgren, Maria, January 2007 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 5 uppsatser.
40	Identification of tumor suppressor genes using the approach of gene inactivation test / Wang, Fuli, January 2006 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2006. / Härtill 4 uppsatser.

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