International Telemetering Conference Proceedings / October 25-28, 1999 / Riviera Hotel and Convention Center, Las Vegas, Nevada / The mathematics basis that can form a telemetry system is orthogonal functions. Three kinds of orthogonal functions are used up to now. First of them is sine and cosine function family. The second one is block pulse function family. The third one is Walsh function family. Their corresponding telemetry systems are FDM, TDM and SDM (CDM). Later we introduced an orthogonal function which is called Bridge function. The corresponding system is named telemetry system based on Bridge function. Now a new kind of orthogonal function, Generalized Bridge function, has been found. It can be applied to practical multiplex of information transmission. In this paper the author provides the design concept, block diagram, operational principle and technical realization of telemetry system based on Generalized Bridge function.