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Towards structural studies of plant LRR proteinsKolade, Olatomirin O. January 1998 (has links)
No description available.
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Genetic dissection of disease resistance signalling pathways in ArabidopsisAarts, Nicole January 2000 (has links)
No description available.
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Transposon mutagenesis of Strepromyces coelicolor A3(2)Fowler, kay January 2002 (has links)
No description available.
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The control of nif gene regulation in Klebsiella pneumoniae in response to fixed nitrogenJack, Rachael January 1999 (has links)
No description available.
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Characterisation of novel genes and mapping of polymorphic markers in the human major histocompatibility complexHsieh, Shie-Liang January 1992 (has links)
No description available.
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Characterisation of the short arm of the X chromosome around Xp11.23Chand, Aarti January 1994 (has links)
No description available.
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Antimetabolic effects of plant proteins on homopteran insect pestsPowell, Kevin Steven January 1993 (has links)
Homopteran insect pests can cause severe economical damage to crop plants by both direct physical means and as vectors of plant viral diseases. They are notoriously difficult insects to control by conventional methods, primarily due to their ability to evolve resistance-breaking biotypes within a relatively short time period. The production of genetically modified crop plants, expressing insecticidal genes, offers a novel method of control for a wide range of insect species. Once suitable gene products, such as plant- derived proteins, have been identified as having insecticidal effect against specific insects in vitro, their effect can be determined in vivo by expressing the relevant gene in transgenic plants. Insect feeding trials were carried out to determine the effects of incorporating a range of plant-derived proteins into artificial diets fed to planthopper, leafliopper and aphid pests and to aphids in planta. The lectins Galanthus nivalis agglutinin (GNA) and wheat germ agglutinin (WGA), and the enzyme soybean lipoxygenase (LPO) were shown to exhibit significant antimetabolic effects towards first and third instar nymphs of rice brown planthopper (Nilaparvata lugens Stal) when incorporated into artificial diet at 0 1% {w/v}, 0-1% (w/v) and 0 08% {w/v} levels respectively. The lectin GNA was also shown to exhibit a significant antimetabolic effect towards third instar nymphs of the rice green leafhopper (Nephottetix cinciteps Uhler) and the peach potato aphid {Myzus persicae Sulzer). A number of inert proteins, lectins, protein inhibitors and enzymes also tested showed relatively little or no effect towards both insects. The mechanism of action of all three effective proteins was examined using BPH as a model insect. As judged by honeydew production, the proteins all had a deterrent effect on insect feeding. However, subsequent toxic effects are also indicated. When fed sub-optimal concentrations of effective proteins in combination no synergistic or additive effects were observed, indicating that pyramiding the genes of these effective proteins would be of no advantage in protecting the crop against BPH.
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The molecular physiology of antibiotic production in Streptomyces coelicolorWilliams, Richard Stephen January 2000 (has links)
No description available.
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p53 epitopes as potential tumour targets for immunotherapy programmes against cancersMcArdle, Stephanie January 2000 (has links)
The tumour suppressor gene p53 is pivotal in the regulation of program cell death (apoptosis), and point mutations within the gene represent the most common genetic alterations in human cancers. This process can result in the overexpression and/or accumulation of mutated and/or wild-type p53 protein within the cell. Cytotoxic T lymphocytes (CTL) play a critical role in the immune defense by recognising peptide/MHC complexes on the surface of virally infected or tumour cells followed by lysis. Therefore, p53-derived peptides are potential candidates for immunisation strategies designed to induce anti-tumour CTL in patients.
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The SEC1 and SEC5 genes of Saccharomyces cerevisiaeEgerton, Mark January 1988 (has links)
No description available.
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