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Consensus Statement on the Use of Near-Infrared Fluorescence Imaging during Pancreatic Cancer Surgery Based on a Delphi Study: Surgeons’ Perspectives on Current Use and Future Recommendationsde Muynck, Lysanne D. A. N., White, Kevin P., Alseidi, Adnan, Bannone, Elisa, Boni, Luigi, Bouvet, Michael, Falconi, Massimo, Fuchs, Hans F., Ghadimi, Michael, Gockel, Ines, Hackert, Thilo, Ishizawa, Takeaki, Kang, Chang Moo, Kokudo, Norihiro, Nickel, Felix, Partelli, Stefano, Rangelova, Elena, Swijnenburg, Rutger Jan, Dip, Fernando, Rosenthal, Raul J., Vahrmeijer, Alexander L., Mieog, J. Sven D. 06 March 2025 (has links)
Indocyanine green (ICG) is one of the only clinically approved near-infrared (NIR) fluorophores used during fluorescence-guided surgery (FGS), but it lacks tumor specificity for pancreatic ductal adenocarcinoma (PDAC). Several tumor-targeted fluorescent probes have been evaluated in PDAC patients, yet no uniformity or consensus exists among the surgical community on the current and future needs of FGS during PDAC surgery. In this first-published consensus report on FGS for PDAC, expert opinions were gathered on current use and future recommendations from surgeons' perspectives. A Delphi survey was conducted among international FGS experts via Google Forms. Experts were asked to anonymously vote on 76 statements, with ≥70% agreement considered consensus and ≥80% participation/statement considered vote robustness. Consensus was reached for 61/76 statements. All statements were considered robust. All experts agreed that FGS is safe with few drawbacks during PDAC surgery, but that it should not yet be implemented routinely for tumor identification due to a lack of PDAC-specific NIR tracers and insufficient evidence proving FGS's benefit over standard methods. However, aside from tumor imaging, surgeons suggest they would benefit from visualizing vasculature and surrounding anatomy with ICG during PDAC surgery. Future research could also benefit from identifying neuroendocrine tumors. More research focusing on standardization and combining tumor identification and vital-structure imaging would greatly improve FGS's use during PDAC surgery.
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新動力?新城市?綠色共識下新能源汽車與上海嘉定區產城融合模式的發展 / New Motion? New City? The Development of New Energy Vehicles and the City-Industry Integration Model in Jiading Under Green Consensus王藝, Wang, Yi Unknown Date (has links)
環境惡化與經濟下行的壓力,讓中國各級政府必須尋求一條有別於過去的集約、創新、綠色的發展道路。在這種背景下,類似新能源汽車等兼具節能環保、產業轉型的一批戰略性新興產業開始興起;而地方在承接與發展這些產業時,則傾向於將產業的發展同地方的城市化相結合,採行「以產業為動力,以新城為依託,以生態為源泉」的產城融合模式。
本文通過實地田野調查對上海市嘉定區發展新能源汽車產業的案例進行研究並認為:地方政府為了應對外部發展環境的變化,選擇「把握發展主動權」引入新能源汽車產業,但其實質為把握地方不變的關鍵性資源,即土地開發權。憑藉新能源汽車所帶來的產業不確定性與「綠色共識」下發展正當性的橋接,地方政府獲得了更大的行為自主性與容錯空間,得以透過產業基地與國際示範區的建立帶動地方整體的空間轉型,進而謀取短期的土地開發利益;但產業發展的長期目標卻在這樣的過程中被推遲乃至消解。經由以上案例,本研究將揭示「產城融合」「城」大於「產」之本質,並深入討論綠色發展成為主流論述之下中國地方發展模式的轉變。 / Under the pressure of environmental deterioration and economic downturn, Chinese government have to seek to find a more intensified, innovative and environmental friendly (green) path to development, which differs from the inherent one. As a result, strategic emerging industries like New Energy Vehicles (NEVs) that bear the target of energy saving, environmental protection and industrial transformation start rising. For local governments who take main responsibility of acting, the way how they implement is to combine the industrial development with local urbanization process, which could be called as City-Industry Integration Model.
This paper research the development of New Energy Vehicles in Jiading District, Shanghai Municipality and argues that in order to adapt to the changes of external conditions, local government chooses to “grasp the developmental initiative” to introduce the NEVs industry. However, the essence of the action is to grasp the changeless local key resources, which is the land development rights. Rely on the industrial uncertainty and the bridging of developmental legitimacy under Green Consensus, more autonomy and fault-tolerant space has been obtained by local government. Moreover, local officials could implement spatial transformation through the construction of industrial base and international demonstration area, and then gain short-term land development interests, which is in the cost of long-standing goal of industry booming. Overall, this research would reveal the fact that urbanization occupies a larger proportion than industrial development in the City-Industry Integration Model, and discuss the transformation of local developmental model in China under the new mainstream discourse of sustainable development.
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