Diabetes Mellitus (DM) and periodontal disease (PD) are both common, chronic and debilitating diseases. This paper will illustrate the bidirectional relationship between the two disease processes and how treatment of periodontal disease can improve the glycemic control and overall health of patients with DM. Multiple studies that will be discussed have shown this relationship and concluded PD treatment improves the health of patients with DM, especially in regards to glycemic control. Unfortunately, at this time there is very little data from large scale studies on this topic. The proposed study intends to perform a RCT to show that non-surgical PD treatment in patients with periodontal disease improves glycemic control, hsCRP levels, and kidney function of patients with diabetes mellitus. The significance of this study cannot be understated. The hypothesized conclusions would provide an adjunct therapy to treat DM and its complications potentially preventing end organ damage and progression of disease, which would help to improve the great healthcare burden of this disease.