Thesis (MSc (Nursing))--Cape Peninsula University of Technology, 2018 / Primary health care (PHC) is a frontline health care approach. It is the point of contact where people are kept well and where their quality of life is improved. All people diagnosed as HIV- positive are retested prior to antiretroviral therapy (ART) initiation to verify their serostatus. ART initiation is seen as a non-emergency treatment that provides many benefits if its initiation is accelerated, for example following up pregnant women after being diagnosed with HIV. However, accelerated initiation may lead clients to start treatment before they are ready to adhere to treatment outcomes. The purpose of this study was to describe the nurse support for young adults during a first antiretroviral therapy visit at an urban primary health care clinic in Malawi. A descriptive phenomenological design was followed at an urban setup in Zomba city, Malawi. The sample was selected through purposive sampling until data saturation was obtained. Individual semi- structured interviews were conducted with young adults aged 19 25 who have visited the clinic for their first ART according to an interview schedule and field notes for around 30 minutes in a private room. The data was analysed using distinctive process and a consensus meeting was held between the researcher and independent coder. The findings of the study could help the PHC services to retain and re-engage the young adults in HIV care and aid the Government of Malawi in achieving its Sustainable Development Goal (SDG) 3. Principles of trustworthiness and ethics were adhered to throughout the research process. Six themes, each with separate categories, emerged from the data analysis on the experience of young adults during their first visit for ART at an urban PHC clinic in Malawi. The results indicated the need for an environment that enhances a client-orientated approach with a focus on holistic well-being. Knowledge management should be used to provide relevant and sufficient information to a newcomer while maintaining ethics under difficult circumstances. The legal environment should have a focus on supporting clients that need comprehensive ART treatment. Motivation of the patient regarding taking antiretroviral treatment (ART) is thus essential. Young adults express the need to be supported by nurses with relevant information, privacy and confidentiality and the trusting client/nurse relationship which could help them to retain in ART care. Recommendations of this study was that nurses should be offered in-service training on youthfriendly programmes which focuses on the health care of young adults during their HIV/ART services. Nurses need to create trusting relationship for the young adults and providing in door game at the waiting area to keep them busy as they are waiting for the services. Nursing managers to lobby for funding to extend the clinic and be role models in providing relevant information to young adults. It was concluded that a first visit was both positive and challenging to the participant s; however, they experienced the health providers on the first visit to be caring and supportive.

Due to the successful rollout of the Antiretroviral Therapy Program, an increasing number of perinatally HIV infected adolescents are emerging into young adulthood throughout Botswana. Young adulthood is a critical period of human development, with long-lasting implications for a person’s economic security, health and well-being. During this time, young women and men normally complete school, find employment and start working, develop relationships, form families, bear children and pursue those things that help set them on the path to healthy and productive adult life. However, the presence of a chronic illness such as HIV can interfere with the achievement of the developmental milestones of young adulthood and affect their Health Related Quality of Life (HRQOL). The purpose of this study was to identify the factors that affected the HRQOL of young adults living with perinatally acquired HIV (YALPH) and to propose policy guidelines to promote their HRQOL. A mixed-methods sequential explanatory research design was used. HRQOL assessments were made using the WHOQOL-HIV BREF instrument. Data about the clinical characteristics of the respondents was obtained from medical records. In-depth interviews were conducted with a purposefully selected subsample of respondents who completed the WHOQOL-HIV BREF instrument. All the respondents were recruited from Botswana-Baylor Children’s Clinical Centre of Excellence, in Gaborone, Botswana. Data were analyzed using SPSS Inc. software version 16.0 (statistical package for social science, SPSS Inc, Chicago, IL, USA). The study population consisted of 509 YALPH including 255 (50.1%) females and 254 (49.9%) males. The mean age of the population was 21.7 (± 2.6) years (range 18-29.8 years). The majority of the respondents were single (98.1%), living in their parental homes (90.8%), neither in school nor working (47.35%) and 14% were parents (range 1-3 children). The mean duration on ART was 12.4 years (± 4.0). Based on the BMI classifications by WHO, 38.5% of respondents were underweight (BMI < 18.5 kg/m2) and 7.3% were overweight (BMI ≥ 25.0 kg/m2). Unsuppressed viral load (>400 cell/mL) occurred in 13.4% of the sample. Most respondents had good HROQL (78.4%). The highest mean HRQOL score was recorded in the Physical domain (15.4 (± 2.9) and the lowest in the Environment domain 13.8 (± 2.7). The results fitted using the multivariable logistic regression suggest the odds for good general QOL were increased amongst individuals with a higher level of education and 6 those who were employed. The odds for good general QOL were reduced for individuals with unsuppressed viral load (> 400 cells/mm2) and those who had illnesses (self-reported). The odds for good general QOL increased by almost two folds (OR = 1.97, 95% CI = (1.11 – 3.48)) when comparing respondents with higher level of education against those with lower education. The odds for good general QOL were increased for employed respondents OR = 1.73 (95% CI = (0.92 – 3.23) when compared to the unemployed group. Whereas the odds for good general QOL declined by almost two folds (OR = 0.60, 95% CI = (0.33 – 1.08)) amongst patients with VL > 400 cell/mm2 compared to those with VL < 400 cells/mm2. Also, respondents who were ill had lower odds ratios for good general QOL compared to those who were not ill (OR = 0.42, 95% CI = (0.25 – 0.70)). The results of in-depth interviews with 45 respondents showed that the majority of YALPH were in good physical health and they had positive perspectives about the future including health, completing school, finding employment, marriage and childbearing. The main sources of social support for YALPH were close family members and health care workers (HCWs). However, worries and concerns about disclosure, fear of stigma, lack of financial independence, and limited social relationships and networks were the most identified stressors that put the YALPH at risk of compromised HRQOL. Some sub-groups of YALPH were at higher risk for poor HRQOL including: young mothers, YALPH who were aging out of institutional care, YALPH with disabilities and impairments, YALPH who were neither in school nor working and YALPH with maladaptive coping strategies. Therefore, the promotion of the HRQOL of YALPH will require policies and interventions to increase educational attainment, provide employment and livelihood opportunities, promote good ART adherence and VL suppression, and effectively prevent and manage illnesses. Special attention should be paid to sub-groups of YALPH who are at increased risk of compromised HRQOL. / Health Studies / D. Litt. et Phil. (Health Studies)

This qualitative study explored the lived experiences of adolescents living with vertically acquired HIV receiving treatment, care and support services at Dora Nginza Wellness clinic, in Port Elizabeth, South Africa. Six adolescents living with vertically acquired HIV (four females and two males) between the ages of 16-17 years participated in in-depth semi-structured open-ended individual interviews. Tesch’s (1990) method of data analysis for qualitative research was used to analyse the interviews. Adolescents that participated in the study spoke widely about the outlook on their illness and their lives both in the past and present. They depicted fear, anxiety, pain and sadness in their lived experiences. They were anxious about their own death and had experienced illness and death of parents, siblings and close relatives due to HIV and AIDS. They described painful and traumatic life events related to their illness which included knowing their own HIV status and severe health problems and hospitalisations. They all learnt about their HIV status in early adolescence and choose not to disclose their status to people outside the family due to fear of rejection, stigma and discrimination. Taking ARVs was challenging to the participants due to side effects and strict medication schedules. Their school attendance and performance was affected by their illness. Family was an important resource of support. The participants had good experiences of HIV treatment at the Wellness clinic. The findings suggest that adolescents living with vertically acquired HIV faced a number of challenges in dealing with their disease and its treatment. They need intensive care and support services that enhance their positive self, facilitate self-disclosure and decrease and discourage stigma and discrimination at school and within their communities. / Health Studies / M.A. (Social Behavioural Studies in HIV/AIDS)

This qualitative study explored the lived experiences of adolescents living with vertically acquired HIV receiving treatment, care and support services at Dora Nginza Wellness clinic, in Port Elizabeth, South Africa. Six adolescents living with vertically acquired HIV (four females and two males) between the ages of 16-17 years participated in in-depth semi-structured open-ended individual interviews. Tesch’s (1990) method of data analysis for qualitative research was used to analyse the interviews. Adolescents that participated in the study spoke widely about the outlook on their illness and their lives both in the past and present. They depicted fear, anxiety, pain and sadness in their lived experiences. They were anxious about their own death and had experienced illness and death of parents, siblings and close relatives due to HIV and AIDS. They described painful and traumatic life events related to their illness which included knowing their own HIV status and severe health problems and hospitalisations. They all learnt about their HIV status in early adolescence and choose not to disclose their status to people outside the family due to fear of rejection, stigma and discrimination. Taking ARVs was challenging to the participants due to side effects and strict medication schedules. Their school attendance and performance was affected by their illness. Family was an important resource of support. The participants had good experiences of HIV treatment at the Wellness clinic. The findings suggest that adolescents living with vertically acquired HIV faced a number of challenges in dealing with their disease and its treatment. They need intensive care and support services that enhance their positive self, facilitate self-disclosure and decrease and discourage stigma and discrimination at school and within their communities. / Health Studies / M.A. (Social Behavioural Studies in HIV/AIDS)