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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
281

Effects of dehydration on hemoglobin oxygen affinity and blood cell volume in two anurans

Zygmunt, Andrew Christopher 01 January 1984 (has links)
Two aspects of possible adaptation In cardiovascular performance caused by Increased plasma electrolytes were examined. Cells In anisotonic plasma may either act as osmometers or volume regulate. Blood flow rate Is dependent upon cell viscosity, which in turn is a consequence of cell volume and membrane deform-ability. Cell volume changes which Increase membrane deform-ability will thus potentially extend the limits of dehydration tolerance. It was found in R. catesbeiana and B. marinus that red blood cell Is maintain constant volume during dehydration. Cells in vitro Initially lose water, but then sodium, potassium and water move Into the cell. Cell viscosity within the physiologic range of hematocrits was higher In salt loaded non-regulating cell Is of B. marinus than In regulating isotonic cells.
282

Bio-separation of Methemoglobin and Oxyhemoglobin using Magnetic Chromatography

Sundar Rajan, Neeraja, Rajan January 2018 (has links)
No description available.
283

CHANGES IN HEMOGLOBIN AND EPIGENETIC CONTROL IN MULTIPLE SCLEROSIS

Alkhayer, kholoud 05 August 2019 (has links)
No description available.
284

Vztah reperfuze plicních tepen po akutní plicní embolii k rozvoji chronické tromboembolické plicní hypertenze. / Relation between the reperfusion of pulmonary arteries after an acute pulmonary embolism to the development of chronic thromboembolic pulmonary hypertension.

Mrózek, Jan January 2019 (has links)
Relation between the reperfusion of pulmonary arteries after acute pulmonary embolism to the development of chronic thromboembolic pulmonary hypertension Incomplete resolution of thromboemboli following acute pulmonary embolism (PE) is a key factor in development of chronic thromboembolic pulmonary hypertension (CTEPH). In our study, we evaluated the incidence, risk factors and clinical impact of incomplete reperfusion after acute PE. Study population and methods: 85 patients after the first acute PE were assessed clinically and by pulmonary scintigraphy and echocardiography at month 6, 12 and 24 after an acute PE. Results: Incomplete reperfusion was detected in 23.5 % of patients after 6 months, in 24.9 % of patients after 12 months and in 18.6 % of patients after 24 months. At month 6, patients with incomplete reperfusion were more obese when compared with patients with normal reperfusion BMI 30.8 vs 28.3 kg/m2 ; p=0.012) and their initial hemoglobin levels were higher (143.0 vs 136.0 g/l; p=0.012). Similar results were observed at month 12 - patients with residual perfusion defects were more obese (BMI 31.1 vs 28.5; p=0.016) with higher initial hemoglobin levels (144.0 vs 136.0; p=0.007). Patients with incomplete reperfusion at month 24 were significantly older (67.7 vs 55.0 years; p=0.02), their...
285

Beta thalassemia: pathogenesis, progression, and treatment

Kitiashvili, Michael 10 March 2023 (has links)
β-thalassemia is an autosomal recessive blood disease caused by mutations in β-globin genes that either reduce or altogether abolish β-globin chain synthesis. Normally, two β-globin chains would combine with two α-globin chains and a heme group to form hemoglobin. Because α-globin chain synthesis is unaffected in β-thalassemia patients, the unpaired α-globin chains accumulate and precipitate. The reduced formation of hemoglobin and accumulation of unpaired α-globin chains are the two fundamental molecular pathologies. In the most serious cases of the disease, the resulting complications develop before two years of age. Most often, these include severe anemia, pallor, jaundice, abdominal enlargement, and distinct craniofacial features. If left untreated, the disease is fatal before the age of three in the most serious cases. Each year, more than 40,000 births, mostly in Southeast Asia, Middle East, or Africa, are affected with β-thalassemia. With increased migration, however, β-thalassemia is becoming more common in Europe and North America. Currently, the most widespread treatment for the disease is transfusions and iron chelation therapy, and the only cure is hematopoietic stem cell transplantation. In recent years, however, multiple treatments and potential cures such as fetal hemoglobin inducers and gene therapy have shown promise. By analyzing the cost-efficiency, viability, and therapeutic benefits of current and future treatments, it can be seen that a combination of fetal hemoglobin inducers, transfusions, and iron chelation therapy will have the greatest impact for the vast majority of β-thalassemia patients.
286

Engineering the Biophysical and Biochemical Properties of Polymerized Hemoglobin as a Red Blood Cell Substitute via Various Strategies

Gu, Xiangming January 2022 (has links)
No description available.
287

The Design and Synthesis of Hemoglobin Nanoparticles as Therapeutic Oxygen Carriers

Hickey, Richard James, III January 2021 (has links)
No description available.
288

DEVELOPMENT OF AN INTEGRATED SOFTWARE/HARDWARE PLATFORM FOR THE DETECTION OF CEREBRAL ANEURYSM BY QUANTIFYING BILIRUBIN IN CEREBRAL SPINAL FLUID

BHADRI, PRASHANT R. January 2005 (has links)
No description available.
289

The Design, Fabrication, and Testing of a Point of Care Device for Diagnosing Sickle Cell Disease and Other Hemoglobin Disorders

Ung, Ryan 31 May 2016 (has links)
No description available.
290

Microcirculatory Effects of Hyperviscous Hemoglobin-based Fluid Resuscitation in a Canine Model of Hemorrhagic Shock

Peruski, Ann Marie 08 September 2010 (has links)
No description available.

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