Coding is an essential technology for efficient fiber-optic communications and secure quantum communications. In particular, low-density parity-check (LDPC) coding is favoured due to its strong error correction capability and high-throughput implementation feasibility. In fiber-optic communications, it has been realized that advanced high-order modulation formats and soft-decision forward error correction (FEC) such as LDPC codes are the key technologies for the next-generation high-speed optical communications. Therefore, energy-efficient LDPC coding in combination with advanced modulation formats is an important topic that needs to be studied for fiber-optic communications. In secure quantum communications, large-alphabet quantum key distribution (QKD) is becoming attractive recently due to its potential in improving the efficiency of key exchange. To recover the carried information bits, efficient information reconciliation is desirable, for which the use of LDPC coding is essential. In this dissertation, we first explore different efficient LDPC coding schemes for optical transmission of polarization-division multiplexed quadrature-amplitude modulation (QAM) signals. We show that high energy efficiency can be achieved without incurring extra overhead and complexity. We then study the transmission performance of LDPC-coded turbo equalization for QAM signals in a realistic fiber link as well as that of pragmatic turbo equalizers. Further, leveraging the polarization freedom of light, we expand the signal constellation into a four-dimensional (4D) space and evaluate the performance of LDPC-coded 4D signals in terms of transmission reach. Lastly, we study the security of a proposed weak-coherent-state large-alphabet QKD protocol and investigate the information reconciliation efficiency based on LDPC coding.