Multiple murder has attracted comparatively little attention amongst academic researchers. The present study offers a description of the phenomenon of Multiple Homicide in England and Wales over a 10 year period based on interviews with perpetrators and study of archival records. Results were analysed in two ways: First, using conventional statistical methods, and second, using multiple sequential functional analysis to challenge existing typologies, highlight the role of psychological process and to emphasise the important role of environmental events. The analysis revealed a very heterogeneous population although experiences such as social isolation and frustration were not uncommon. Unlike the perpetrators described in many American studies histories of physical and sexual childhood abuse and neglect were not the norm in this population and were felt to have little association with multiple murder. The issues raised by the methodology and the implications of the study for profiling, identification of possible offenders, treatment targets, and future areas of research are discussed.