Thesis--Paris, 1937. / "Index bibliographique": p. [373]-380.

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No description available.

The major histocompatibility complex (MHC) is a genomic region comprised of a linked cluster of genes and gene families that play an important role in both the adaptive and innate immune responses. Genes within the MHC have also been associated with susceptibility and/or resistance to certain diseases, such as haemochromatosis, insulindependent diabetes, and psoriasis. As a result of these associations the MHC is one the most extensively studied regions of the mammalian genome. The MHCs of a wide variety of species, such as human (HLA), mouse (H-2), pig (SLA), and cow (BoLA), have been characterized with respect to gene content, genomic organization of class I, class II, and class III regions, and comparative organization. Comparative analyses have been useful in delineating the evolutionary development of the MHC. While the MHC of many mammalian species has been investigated, little research has been performed on the equine (Equus caballus) MHC. The equine MHC is referred to as the equine lymphocyte antigen (ELA) complex and is located on chromosome ECA20q. The research that has been done on ELA focused on identifying gene copy number and genetic polymorphisms in the classical class I and class II genes. To better characterize the gene content and organization of ELA, we isolated 103 bacterial artificial chromosome (BAC) clones from a horse BAC library containing well conserved genes found within mammalian MHCs. These BAC clones were assembled into two sequence-ready ordered contigs that span the ELA complex. The first contig which has a minimum tiling path of nine BAC clones contains the ELA class II region and spans 800 kb. The class I and III regions are contained within the second contig which has a 14 BAC clone minimum tiling path and spans 1.6 Mb. This study will report on the construction of the two BAC contigs which span the ELA complex, and characterization of the gene content and organization of the ELA complex.

The aim of this study was to determine the effects of density and provision of water on behavior, stress, and weight loss in slaughter horses during transport. A 16.2-m long, single deck, semi-trailer was divided into three compartments to create high, medium, and low density (5000, 4000, and 3000 kg per compartment, respectively) groups of slaughter horses. A total of six shipments containing 23 to 30 horses per shipment were transported in June and July of 2004 for 18 to 20 h. Horses were a variety of different breeds, ages, sexes, and body conditions, but were typical of slaughter horses. Jugular blood samples were taken from five horses in each of the three density treatments immediately before loading and after unloading at the completion of each shipment. All horses were weighed at the same time as the blood samples were collected. While the truck was stopped, horses in each of two compartments received water from three automatic water bowls in each side of a compartment. The water was provided for 1-h after 8 h of transport and then again just prior to unloading. The third, non-watered compartment served as a control for each of the 1-h watering sessions. Densities selected to receive water were alternated between shipments. The aggressive behavior of the horses for the six shipments was recorded using 12 video cameras installed in the trailer. All occurrences of aggressive behavior were counted from 15-min segments of video during 2-h intervals for each horse that was visible in each density group. Density did not significantly affect (P > 0.21) aggressive behavior, cortisol, serum chemistry profile, dehydration, and weight loss. Aggression level did not differ (P = 0.49) between the first and second halves of the shipments. Individual horses, rather than density, appeared to be the cause of aggressive behavior. The watered and non-watered groups did not differ (P > 0.54) in terms of aggression, cortisol, serum chemistry profile, dehydration, and weight loss. Density and provision of water did not significantly influence aggressive behavior, stress and weight loss in shipments of 18 to 20 h long during warm weather.

Thesis (M.Sc.(Agric.)(Animal Science))--University of Pretoria, 2003. / Summaries in English and Afrikaans.

Thesis (B.E.(Hons.))--University of Adelaide, 1986. / Cover title. "Submitted as partial fulfillment of the requirements for the degree of Bachelor of Economics (Hons) at the University of Adelaide, 1986." Includes bibliographical references (p. 128-131).

Thesis (Ph. D.)--Catholic University of America, 1944. / Includes bibliographical references.

Thesis (M.S.)--Wisconsin. / Includes bibliographical references (leaves 128-133).

Thesis (M.S.)--University of Wisconsin--Madison, 1937. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves i-ii).