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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Correlação da candidose com a atividade proliferativa epitelial em leucoplasias da mucosa jugal /

Baldan, Renato Costa Franco January 2005 (has links)
Orientador: Marcelo Macedo Crivelini / Resumo: Tem sido descrito que cerca de 30% do total leucoplasias possui tendência à malignização, a uma taxa de 2,9% ao ano. O envolvimento concomitante de leucoplasias com Candida albicans tem sido relacionado a possíveis processos de malignidade, tornando este questionamento uma fonte de debate. O presente trabalho avaliou a expressão qualitativa de p 53, Ki-67, PCNA e AgNOR em leucoplasias associadas à Candidose. Não foram observadas diferenças significativamente estatísticas (Tukey test, p<0,05) no grupo corado por AgNOR. Esses resultados discutem a taxa de proliferação celular epitelial e, talvez, indícios de alterações genéticas malignas presentes nas leucoplasias associadas à Candidose. / Abstract: It has been described that 30% of leukoplakia with tendences to malignization, in a rate of 2,9% per year. The envolvement of leukoplakia associated to Candida albicans has been related to possible process of malignity, witch makes this question a source of debate. The aim of this study was to evaluate the qualitative expression of p53, Ki-67, PCNA and AgNOR in leukoplakia related to Candidosis. It wasþt observated statistical diferences in the AgNOR group (F test, p<0,05-ANOVA one-way). This results discuss a rate of celular epitelial proliferation and possibly genetic alterations present in leukoplakia related to Candidosis. / Mestre

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