Diss. Linköping : Linköpings universitet, 2006.

Bibliography: leaves 234-257. Three separate clinical studies in organ transplant recipients are presented. The aims are to examine fundamental questions regarding the clinically and economically important pharmokinetic interaction between diltiazem and cyclosporin, an interaction widely utilised in organ transplantation. The data contained should assist the development of soundly based policies that will ensure a benefit exists before a sparing agent is coprescribed, and that the lowest effective dose of sparing agent is used.

Bibliography: leaves 234-257. / xi, 277 leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Three separate clinical studies in organ transplant recipients are presented. The aims are to examine fundamental questions regarding the clinically and economically important pharmokinetic interaction between diltiazem and cyclosporin, an interaction widely utilised in organ transplantation. The data contained should assist the development of soundly based policies that will ensure a benefit exists before a sparing agent is coprescribed, and that the lowest effective dose of sparing agent is used. / Thesis (Ph.D.)--University of Adelaide, Dept. of Clinical and Experimental Pharmacology, 2001

This research is part of an effort to develop non-mammalian surrogate immunoessays with the earth worm Lumbricus terrestris to assess immunotoxic potential of xenobiotics to mammals. The objective was to determine if earthworm immunoessays, namely E- and S- rosette formation and phagocytosis, are sensitive to a known mammalian immunotoxin, the PCB Arclor 1254. Results are presented in terms of PCB exposure and tissue concentrations during uptake/depuration.

Call number: LD2668 .T4 1978 L38 / Master of Science

published_or_final_version / Surgery / Doctoral / Doctor of Philosophy

by Wong Dart-man. / Bibliography: leaves 107-114 / Thesis (M.Phil.)--Chinese University of Hong Kong, 1982

C57B1/6 mice bearing Lewis lung carcinoma CLLC) are suppressed in their ability to generate cytotoxic T lymphocytes against the LLC tumor associated antigens. Since LLC have previously been shown to secrete the immunosuppressive factor PGE2, indomethacin, a prostaglandine synthetase inhibitor, was administered to LLC-bearing mice in their drinking water to prevent the immunosuppression typical of tumor bearers. The indomethacin treated tumor-bearers displayed an increase in their cytotoxic responses to the LLC tumor associated antigens. Thus the immunosuppression found in mice bearing LLC could be due to prostaglandin synthesis. Production of PGE2 by tumor cells may be a mechanism by which the tumors escape immune mediated destruction.Ball State UniversityMuncie, IN 47306

Thesis (Ph. D.)--University of Hong Kong, 2009. / Includes bibliographical references (leaves 188-245). Also available online.

Thesis (Ph. D.)--Oregon State University, 2010. / Printout. Includes bibliographical references (leaves 132-156). Also available on the World Wide Web.