Thesis (M. Med. Sc.)--University of Queensland, 2000. / Includes bibliographical references.

Thesis--PlanB (M.S.)--University of Wisconsin--Stout, 2002. / Includes bibliographical references.

Thesis (M.S.)--Eastern Illinois University, 2003. / Includes bibliographical references (leaves 31-34).

Thesis (Ph. D.)--University of Oregon, 2002. / Typescript. Includes vita and abstract. Includes bibliographical references (leaves 207-214).

Thesis (Ph. D.)--Ohio State University, 2003. / Title from first page of PDF file. Document formatted into pages; contains xiii, 155 p.: ill (some col.). Includes abstract and vita. Advisor: Tammy Bray, Nutrition Program. Includes bibliographical references (p. 139-155).

Thesis (Ph.D.)--University of Central Florida, 2009. / Adviser: Viatcheslav Kokoouline. Includes bibliographical references (p. 125-138).

Objective: Although studies have demonstrated that the media-portrayed thin-ideal images and social comparison processes increase body dissatisfaction and negative affect, research has not tested whether women experience pluralistic ignorance by believing that the thin-ideal is an achievable norm. Method: In Study 1, 172 women completed a questionnaire that assessed the extent to which a participant believed that the thin-ideal body image represented the normative body size among women. In Study 2, 356 women participated in a five condition experiment that manipulated the body size of an attractive college student (i.e., thin-ideal or average-sized) and information about the achievability of the woman’s body size (i.e., achievable, not achievable, or no information). Results: Study 1 found no evidence that thin-ideal norm endorsement affected body dissatisfaction or negative affect. Study 2 revealed an increase in body dissatisfaction but not negative affect in the thin-ideal achievable and thin-ideal no information conditions. The results also indicated a marginally significant decrease in negative views of the self in the average-sized achievable and average-sized no information conditions. Furthermore, participants with low self-esteem or poor social support felt better in the average-sized achievable condition when compared to the thin-ideal achievable condition. Also, participants with a higher BMI felt more depressed in the thin-ideal achievable condition when compared to the average-sized achievable condition. Discussion: Results suggest that thin-ideal norm endorsement increased body dissatisfaction by way of social comparative processes and perhaps, pluralistic ignorance. Because participants with low self-esteem or poor social support felt better after seeing an average-sized peer who was said to be the achievable ideal, these results have implications for clinical treatment and prevention interventions. / text

published_or_final_version / Chemistry / Doctoral / Doctor of Philosophy

No description available.

RCK (regulating the conductance of K+) domains are ubiquitous among a wide variety of cation translocation systems or channels. Whether it is inward or outward transport, RCK domains share high sequence similarity from protein to protein, suggesting that they perform important functions in these systems. Although specific functions are not yet fully understood, RCK domains bind nucleotides, a characteristic that has been suggested to be important for the open/closed transition. In some cases RCK domains can bind additional ligands, e.g. KefC binding to glutathione. This project provides an in-depth study of two equally important bacterial potassium uptake systems, Trk (from E. coli) and CglK (from C. glutamicum). In these systems, RCK domains form octamers that either are anchored (CglK) or are separate and bind to transmembrane partners (Trk). The overall objective of this study was to examine the ligand control of the Trk potassium uptake system, including ligand identification and binding effects on its conformation, and therefore activity control. A crystal structure of the Trk potassium uptake system from Vibrio parahaemolyticus, was published recently [1] and provided evidence of ADP/ATP switch as a control mechanism. In accordance with the aforementioned study, the work presented in this thesis provides strong evidence that both ADP and ATP can bind to E. coli TrkA. Furthermore, it was shown that NADH bind strongly to one of the two RCK domains present in TrkA protein. The data presented here suggest a more complex control mechanism of the E. coli Trk system. CglK is a major potassium uptake system of C. glutamicum, but little is known about its control mechanism. The mutagenesis approach was undertaken to learn more about the system and its underlying processes/mechanisms. The work shown in this thesis indicates a similarity of CglK to other potassium channels, such as MthK and GsuK. The functional mechanisms proposed for those two systems were proven to be similar to that of CglK, although the specific CglK activation ligands are still to be found.