No abstract available. / Thesis (M.A.)-University of Natal, Durban, 1978.

No abstract available. / Thesis (M.D.)- University of Natal, Durban, 1987.

No abstract available. / Thesis (M.Com.)-University of Natal, Durban, 1966.

No abstract available. / Thesis (Ph.D.)-University of Natal, Durban, 1983.

The main aim of this study is to provide a social geography of one of the less privileged communities in South Africa. The township of Merebank, about 15 km west of Durban was chosen as the study area.In order to assess social well being of residents conventional social indicators relating primarily to economic well being were used. Furthermore,access to opportunities was evaluated to determine social well being in a broader context. All aspects of quality of life cannot bemeasured in monetary terms alone and the degree of access a person may have to an amenity or service may often be a far more meaningful measure of social well being. The study also provides useful information about socio-economic conditions in Merebank, attitudes of residents, and positive and negative features of the residential environment. A number of recommendations are suggested which if implemented by planners, can help amelioriate problems and improve the quality of life in Merebank. / Thesis (M.A.)-University of Durban-Westville, 1983.

No abstract available. / Thesis (M.S.U.R.P.)-University of Natal, Durban, 1976.

No abstract available. / Thesis (M.A.)-University of Durban-Westville, 1975.

Objective: To determine the role of candidate gene polymorphisms in patients who sustained myocardial infarction at a young age and examine their relationship, if any, to risk factors. Since angiotensin II is known to play a pathophysiological role at the myocardial and vascular level, the genes to be studied are those regulating the renin angiotensin system and tissue metabolism. Design: The risk factors and genetic profile is described in 117 young Indians with myocardial infarction recruited over a period of thirty months (Dec 1997 - Jun 1999). Controls comprised 80 normal subjects with no clinical evidence of coronary heart disease (CHD) and with a normal effort response. The key features of this study are the selection of young subjects with myocardial infarction, (mean age 43 ± 6.8 years) in whom the possibility of a genetic basis for the disease was felt to be more likely since the confounding effect of age as a risk factor was reduced. Setting: Patients recruited 3 -12 months after myocardial infarction from Addington Hospital, Durban. This hospital subserves the Indian community in the north of Durban. The majority of patients were from the Phoenix settlement area. Results: 1. The clinical profile of the young Indian with myocardial infarction is a young man, slightly overweight with a high prevalence of risk factors, particularly smoking and diabetes, coupled with sedentary behaviour and risk-prone dietary patterns characterised by high red meat intake and low fruit and vegetable consumption, resulting in increased BMI and W/H ratios. 2. There were no differences in the patterns of gene polymorphism in the reninangiotensin system between the study and control groups. This finding extended across all candidate gene loci studied i.e. those involving aldosterone, G-protein, TGF-B and homocysteine metabolism. Serum triglycerides, haemoglobin AlC and urine microalbumin levels were elevated in the probands together with low HDL-C levels (p = 0.001). 3. A striking finding of this study was the substantial proportion of patients found to have diabetes mellitus, totalling 47% of the proband group. Of the 53 diabetic patients, (45 males and 8 females) four (3 males, 1 female) had impaired glucose tolerance. Cigarette smoking, a positive family history of hypertension/diabetes and a family history for premature CHD emerged as important risk predictors for MI. Conclusion: This study, the first to report candidate gene polymorphisms in young Indians with coronary heart disease, has shown no obvious association between the genetic loci studied and acute myocardial infarction. Instead a high prevalence of risk factors, particularly smoking and diabetes mellitus, coupled with coronary-prone behavioural patterns was observed. In the light of these findings, genome-wide screening of unaffected siblings of subjects with early onset CHD cannot be recommended in this population until common polymorphisms can be clearly identified as risk factors. Indeed this study again supports the dire need for early, school level, education in behavioural lifestyle patterns and disease predisposition. The Indian community is a very high-risk group who should be targeted, not for secondary, but for primordial disease prevention measures. The study does not rule out the role of other candidate gene polymorphisms in the pathogenesis of CHD in these subjects. The high prevalence of diabetes and insulin resistance suggests that studies of genes regulating glucose and lipid metabolism should be pursued. Such candidate genes should include genes for lipoprotein lipase and paraoxonase polymorphisms which may explain the dyslipidaemia patterns in this group. / Thesis (Ph.D.)-University of Natal, Durban, 2000.

No abstract available. / Thesis (M.D.)-University of Natal, 1982.

This thesis seeks to examine Indian political development in South Africa during the period 1933-1939, with specific reference to the emergence of the Colonial-Born and Settlers' Indian Association and its influence on the course of Natal Indian politics. The primary aim of the thesis is to examine the role played by this Association in obstructing the Union government's assisted emigration plans and colonisation scheme. To achieve this aim it was necessary to examine the establishment of the Association and to determine whether the Association fulfilled its main objective. After a brief exposition of early Indian immigration, the activities of the successive Agent-Generals are examined in the context of their relationship with the Natal Indian Congress (NIC) and the Association and how these diplomats articulated the aspirations of their government. The Agency attempted to secure improvements in the socio-economic position of the South African Indian community. In terms of various directives from the Indian government it was clear that they emphasised the value of negotiations and compromise and aggressively suppressed the strategies of those who opposed this approach. This attitude surfaced particularly in its relationship with the Association relative to the Association's stance on the colonisation issue. Notwitstanding the disabilities experienced by the Association in its fight for the equal status of its supporters and for the right to remain in South Africa, the Association is seen to have succeeded in the realisation of its fundamental objective. The thesis also seeks to establish that there was a need for the creation of the Association and later after it had served its function the need for its dissolution. In this process the author also deals with the general activities of the Association and the crucial negotiations conducted with the Congress to the point of amalgamation in 1939 when the Association and the NIC amalgamated to form the Natal Indian Association. The significant influence of the Agency in the process of negotiations is emphasised. There are three main themes in this study. The first reflects the manner In which the moderate leadership articulated the aspirations of their supporters. Secondly, it demonstrates the internal differences, sectionalism and the class struggles within the Indian organisations. , The third theme seeks to reveal the often devious roles played by the respective governments, their intransigence, connivance and particularly the apathy of the government of India. / Thesis (M.A.)-University of Natal, Durban, 1992.