This research project focused on the narrated lives of woman informal street traders. Ten women from the Warwick Junction market in Durban, South Africa, of varying ages, were interviewed. The women selected participated in two interviews, one narrative interview and a follow up in-depth open-ended interview based on their life narrative. Thematic analysis was conducted thereafter; through this process recurring themes relevant to all participants were identified and discussed. Five dominant themes resulted from the thematic analysis: ‘Economic challenges’; ‘Politics, police and permits’; ‘Work’; ‘Being a woman’ and ‘Support’. The findings of this research showed that economical challenges were a substantial issue for several of the women, many of who grew up in poverty and remain trapped in the poverty cycle. Disturbingly, several women highlighted how local authorities and corrupt police showed little regard towards trader’s opinions and several women nostalgically recollected trading conditions before 1994. Many of the women were the sole breadwinners for their families, supporting children and grandchildren and great emphasis was placed on the importance of their work as a means of economic survival and financing their children’s education, as schooling was understood to be leverage out of the poverty cycle. The supportive role of the women’s communities was a significant feature in their lives. Several overarching social networks became resources in times of crises. The need to utilize the community as a supportive network was largely due to the lack of formal support women informal street traders received from local authorities. This research raises concerns over the City’s perceptions of, and approach towards, informal street traders, specifically in the last decade. Furthermore, this study highlights the need to broaden understandings of the means of coping used by women in contexts of poverty, constant vulnerability, and exposure to frequent psychologically disturbing trauma.

Thesis (M. Sc. (Microbiology)) --University of Limpopo, 2019 / Informal street traders and traditional health practitioners at Ga Maja (Limpopo Province) primarily offer consumers semi-processed herbal concoctions that are indicated to have blood-cleansing, immune-boosting, detoxifying, antidiarrheal, antiHIV/AIDS and pain-relieving therapeutic properties. The focus of this study was to validate the pharmacological effects and safety of these herbal concoctions as indicated by the traders. Five herbal concoctions and their medicinal plant recipies used for their preparation were purchased from five independent traders. A laboratory concoction was prepared according to the traders’ instructions. Possible microbial contaminants were identified using Matrix-assisted laser desorption/ionisation time-offlight mass spectrometry and VITEK 2. Nutritional content of the concoctions was determined by a plasma atomic emission spectrophotometer. Qualitative phytochemical analysis was determined using standard chemical tests and thin layer chromatography. Total polyphenol content was quantified calorimetrically. Antioxidant activity was quantified using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing power assays. Antimicrobial activities were determined using a broth micro-dilution assay and bioautography. Anti-HIV-1 reverse transcriptase activity was used to determine the antiviral potential of the concoctions. Anti-inflammatory activity was determined using the cyclooxygenase inhibition assays and possible cytotoxic effects of the concoctions were evaluated using MTT cell viability assay. Growth on potato dextrose and nutrient agar plates indicated heavy microbial contamination. Sodium, potassium and zinc were most abundant in the concoctions. The concoctions had similar phytochemical profiles, and together with plant decoctions consisted primarily of polyphenolic constituents. Generally, some plant decoctions had higher antioxidant (EC50: 15.71 – 40.87 µg/mL) and antibacterial (MIC: 0.04 – 0.63 mg/mL) activities. The antimicrobial activities of the concoctions were as a result of synergistic effects of the compounds because no single compound was observed to have antimicrobial activities on the bioautograms. Combination studies showed that the combination of crude decoctions from different plant species resulted in reduced antioxidant, antibacterial and antifungal activities. The laboratory concoction had higher anti-HIV reverse transcriptase activity (EC50: 2.90 µg/mL) than the positive controls used (EC50: 36.65 – 40.90 µg/mL). The concoctions also demonstrated considerable antiinflammatory activity. The lack of standardisation of phytomedicines reduces their xxi pharmacological potential and consistency. However, this study validated the ethnopharmacological use of the different plant species and herbal concoctions towards the treatment of human immune-deficiency virus, pain caused by inflammation, infectious diarrhoea and for immune-boosting. This study also highlighted the complexities associated with combinations of aqueous extracts and the importance of appropriate knowledge on which plant species are to be mixed to enhance their therapeutic properties. Although the concoctions did not exhibit cyctotoxic effects, toxicities may arise from endotoxins produced by the microbial contaminants. Hygienic processing and packaging are essential to ensure that consumers receive quality products that are safe to consume.