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Background: Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) is an immune mediated neuropathy with variable presentation ranging from symmetrical paralysis to a variety of focal manifestations progressing slowly or in a fluctuating pattern. There is no information about the condition in Africa. Method: A Prospective case series of CIDP patients defined according to the criteria of Saperstein. Patients were recruited from the Johannesburg Hospital, South Africa, over a 2-year period. Results: 26 patients were identified. The male to female ratio was 1: 2 with an average age of 41 years. 10 patients were HIV positive. All were black females. There were no differences clinically between the HIV positive and HIV negative groups. The CSF proteins level was raised in only 42% of patients. Conclusion: The patients seen by us at the Johannesburg hospital have a younger age of onset and a female predominance. HIV was identified in 40% of our patients.

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MMed, Ophthalmology, Faculty of Health Sciences, University of the Witwatersrand, 2009 / Aim: To describe and analyse donor demographics; source, utilisation and distribution of corneal tissue procured by the Gauteng cornea and eye bank (GCEB). To further establish the indications for penetrating keratoplasty done by private ophthalmologists in Johannesburg. Methods: A retrospective study of the records from the GCEB for the 8 year period from 1998 to 2005. An analysis for each year was done in respect of donor demographics; corneal donor tissue source and distribution. Records from selected corneal surgeons in private practice in Johannesburg were analysed for indications for penetrating keratoplasty. Results: During the study period, 2504 corneas were retrieved from 1252 donors. The average number of donors per year was 157 (Standard deviation: 20.01). There was a statistically significant increase in the number of donors over the study period (B-coefficient = 6.40, standard error=2, 07, p-value=0.02). Majority of donors were males (68.6%). The mean age of donors was 40.4 years (Standard deviation: 15.97) and ranged from 3 months to 78 years. Whites were in overwhelming majority compared to other races, accounting for 96% (number=1205), followed by Blacks 2% (number=24), Asians 1% (number=18) and Coloureds <1% (number=5). The proportion of donated corneas used for transplantation (corneal utilisation rate) averaged 87%. This rate showed a significant decline over the period studied (Bcoefficient= -1.76, standard error=0.48, p-value=0.01). The commonest reason for discarding corneas was damaged corneas (36%), followed by Human immunodeficiency virus infection (18%) and inconclusive blood results (14%). The majority of donated corneas were used in private practices (91%). vi The majority of donors were referred by mortuaries (50%) and private hospitals (37%). The commonest indication for penetrating keratoplasty was keratoconus (46.8%), followed by corneal scarring (27.8%) and pseudophakic bullous keratopathy (10.1%) Conclusions: This analysis shows that the number of donors increased annually over the study period. There were very few Blacks donating corneas in Johannesburg and most of the referrals were from mortuaries and private hospitals. The distribution of corneal tissue in areas served by the Gauteng cornea and eye bank is in favour of private hospitals. Corneal tissue damage and HIV infection were the commonest reasons for discarding corneas. In private practices in Johannesburg, keratoconus was the commonest indication for penetrating keratoplasty, followed by traumatic corneal scarring.

MCom (Research) , Faculty of Commerce, Law and Management, University of the Witwatersrand, 2007 / The purpose of this dissertation is to motivate, construct and test the suitability of the Fama and French (1993) three-factor model in pricing equities listed on the Johannesburg Stock Exchange. Before this can be achieved, however, the existence of the size and the value effects needs to be established, and their resistance to risk adjustment with traditional asset pricing models needs to be ascertained. Once, these two empirical facts are documented, the three-factor model is built and tested. Results of Fama and French (1992) can be replicated on the Johannesburg Stock Exchange in that a firm‟s size and its value-growth indicator have reliable power to forecast stock returns. However, the value effect and, in particular, the size effect, attenuate after market microstructure is controlled for. Both effects are found to be independent of one another and the book-to-market ratio is found to be the best value-growth indicator. The static CAPM and an APT variant cannot explain the size and the value effects. This result is robust to time-series and cross-sectional tests. The three factor model of Fama and French (1993), and its variant, are constructed. The models can capture a substantial amount of time-series variation in most assets. When applied to the size and book-to-market sorted portfolios, they are not rejected in the vast majority of asset pricing tests. In tests on ungrouped data, the three factor model can explain the value effect, but not the size effect. However, in cross-sectional tests that use the size and book-to-market sorted portfolios as well as industry portfolios, the pricing errors of the three factor model are not substantially different from the ones obtained from the static CAPM.

ABSTRACT The tourism industry has been described as one of the world’s highest priority industries and has emerged as a significant sector in many global economies including South Africa. The global fashion industry is also a multi-billion dollar industry and in many parts of the world is a huge draw card for tourists. Cities like Paris, Milan and New York have long been acclaimed for their thriving fashion industries. In recent times non-traditional fashion cities such as Kenya, Beirut, Lyon and Amsterdam have increasingly looked to the fashion industry for economic and tourism development. The South African fashion industry has flourished in recent years with the emergence of a new genre of design houses redefining South African fashion. It is against this background that the focus of this study was to investigate the link between fashion and tourism in the city of Johannesburg. A review of the policy framework surrounding the cultural and tourism industries was conducted to ascertain the role and importance ascribed to the tourism and cultural industries in South African policy with particular emphasis on the city of Johannesburg’s policy environment. The international experience of using fashion in tourism and urban development strategies provided examples and insight into global strategies of linking fashion and tourism. Case studies of the Johannesburg Fashion District and SA Fashion Week revealed their emerging role in the tourism industry. The experience and views of designers and industry officials regarding the role of fashion in the tourism industry was determined through in-depth semi-structured interviews. The study concluded that there is definitely potential for the local fashion industry to make a significant contribution to tourism in the city of Johannesburg but this is dependent on the development of a clear fashion tourism policy framework, greater marketing and promotional efforts and the addressing of critical challenges in the fashion and cultural tourism sectors.

Master of Commerce - Accounting There are 1 files which have been withheld at the author's request. / Since the identification and documentation of a day-of-the-week effect, it has captured imagination of the investing public and the attention of researchers. Indeed a significant amount of research has been dedicated towards the day-of-the-week effect. Until recently, the results of such research were consistent in that the evidence seemed to indicate that a day-of-the-week effect may indeed exist throughout the world. More recent studies have, however, produced different results and a second body of evidence is developing which indicates that the day-of-the week effect is dwindling. Attempts by researchers to attribute the day-of-the week effect to the settlement practices of various exchanges have met with limited success. This study argues that one would expect traded prices on an exchange to incorporate an adjustment for the delay between transacting and settlement. A model is formulated to adjust the mean daily returns on the exchange for the particular exchange’s settlement practice. This model is tested against historic price data from the Johannesburg Stock Exchange. The evidence presented does not support the notion that the traded prices are adjusted for the delay between the transaction and the settlement, the overall conclusion is that the settlement effect may represent a Johannesburg Stock Exchange inefficiency, though the size and significance of the effect has decreased in recent times

Bibliography: pages 143-149. / A struggle for control of the means of production and surplus is constantly played out between those who 'legally' possess the instruments of production - the bourgeoisie, and those who operate, but are alienated from, the means of production - the working class. This struggle manifests itself in countless ways and never retains the same form: the bourgeoisie always seeks fresh methods to keep the proletariat beneath its yoke, while the proletariat itself always forges new ways of counteracting the bourgeoisie's exploitative measures. It is the contention of this work that from 1917 to 1920 a phase of heightened class struggle occurred in South Africa between the African working class and the bourgeoisie in the form of its representatives in both government and the employing class. As we shall see in the chapters which follow, labour spontaneously confronted capital; it made certain demands on the capitalist system and the stage seemed set for a long and traumatic battle between the controllers and the operators of capital. Yet, as suddenly as it began, the popular militancy of the 1917 to 1920 period evaporated; in its stead came a period of dominance by petty bourgeois organisations accompanied by a decline of working class protest. This dramatic change in the quality of working class resistance merits discussion, and to this end a number of questions can he raised: (1) What gave rise to the growth of militancy during and after the First World War? (ii) What happened to this militancy after the War, and what caused it to go into decline? (iii) If militant class confrontation disappeared, what form did the conflict then take, and what new relations between the differing classes came about?

Refugee camps are an example of ‘post crisis’ rehabilitative systems, which vainly attempt to restore stability in a state of disaster (Azmara, 2012). Uprooted from their homes and thrust into volatile and unfamiliar surroundings, civil conflict and natural disasters have left millions of refugees around the world destitute in their host countries, stripped of their identity and humanity and left with only the clothes on their backs. Unlike in rural settlements, the urban settlement patterns of refugees in Johannesburg have demonstrated a unique gravitational shift from reliance on local government assistance to a strong and long standing affiliation with various religious fraternities in the urban centres. This has then resulted in the inquisitorial search of how well have these urban churches served the needs of the urban displaced communities? By opening up their church buildings to refugees as a place sanctity and solace, how has this spiritual affiliation effected the reception, protection and rehabilitation of psychologically and physically traumatized refugees and asylum seekers? Subsequently has Johannesburg as a city, made provision for the sheltering and protecting of refugees, should there ever again be a crisis of violent xenophobic turmoil in the city’s townships? This thesis seeks to explore the underlying differences between designing a post crisis emergency shelter and specifically developing a transitory sanctuary tailored for urban refugees. By merging the dissimilar approaches assumed by secular refugee aiding organisations and the religious fraternities, the design starts to illustrate the symbolic connection between refuge and solace; spirituality and rehabilitation, as well as making note of the harmonies that exist within humanitarian architecture and sacred architecture. By understanding these fundamental parallels, a premise is formed for the development of a unique and prototypical urban refugee centre, located in Hillbrow, at the heart of Johannesburg’s eclectic foreign national communities. The centre is comprised of several emergency relief facilities, rehabilitative programmes as well as an adaptive form of transitional accommodation all encompasses within a spiritual, yet nondenominational Christian church establishment; a gesture which serves to highlight the ‘curative’ relationship between the spirituality, architecture and the user.

Truth telling forms part of the contemporary debate in clinical bioethics and centers around the right of the patient to know honest information concerning his or her medical condition / illness and the duty of the doctor to inform the patient of such. Anecdotal evidence seems to imply that patients have concerns with the practice of truthtelling. Many often complain that they are not being informed and sometimes simply being ignored in matters that primarily concerns their health. On the other hand, there may be patients who do not to want a truthful answer to their health problems-they would in fact rather not know. The aim of this study was to explore my intuition that patients who attend the Johannesburg General Hospital are not given full information about their condition(s) and / or treatment(s) although they would like to know. The study explored the preferences of patients regarding the practice of truth telling and their attitudes toward truth telling in four out patient clinics of the Johannesburg General Hospital. Four hundred and sixty five participants completed and retuned the questionnaire from four different out patient clinics, namely oncology, surgical (general surgery and orthopedics), medical (gastro, renal and general internal medicine) and the nuclear medicine unit that represented the mixed out patient clinic. The majority of participants stated that the doctor had disclosed information about their condition (92.90%). Almost all participants were of the opinion that patients have the right to know about their condition (98.28%) and also that the doctor has the duty to inform them of their condition (98.02%). If they were suffering from a serious condition, a higher percentage of participants (86.28%) would prefer to know about their condition while a small but significant percentage (13.72%) would prefer not to know. The vast majority of participants (96.64%) also preferred to know about information relating to their treatment in detail while a high percentage (87.83%) supported disclosure to relatives. Variables such as gender, age and level of education did not seem to impact on the participants’ opinions of the truth telling process with significance with the exception of iv gender in relation with knowledge of one’s condition (p=0.0176) and education with regard to opinions on the right of patients to disclosure (p=0.0430). From the above results it can then be concluded that: 1. Participants in our study supported the right of patients to disclosure and the vast majority also felt that doctors have the duty to inform patients of their condition. 2. A significant percentage of participants felt that the level of information given to them was not satisfactory even when they have requested for more. This should be looked at and means for improvement should be sought. 3. A small but significant group did not support disclosure and must be respected as autonomous beings. 4. Gender seems to influence opinions of patients concerning their condition and education impacts on opinions relating to right of patients to disclosure of information. 5. To our appeasement, we found that patients attending the Johannesburg hospital are in fact given information about their condition. It is rather the quality and the quantity of information given that should be subject to scrutiny if we would like to move towards full disclosure in the process of truth telling in our institution. 6. Future studies should be considered to assess the attitudes of doctors towards disclosing, as well as further assess conflicting opinions in small group of patients by means of direct interviews.