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značení proteinů / Synthesis of "Chemical Tags" and their application for selective protein labellingProkešová, Kristína January 2014 (has links)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Drug Control Student: Kristína Prokešová Supervisor: doc. PharmDr. Miroslav Miletín, PhD. Consultant: Dr. Richard Wombacher Title: Synthesis of "Chemical Tags" and their application for selective protein labelling This diploma thesis is aimed on the synthesis and application of chemical tags. In theoretical part, protein labelling in general is discussed and fluorescent proteins, as routinely used technique for protein tracking, are shortly presented. The greatest attention is dedicated to chemical tags which consist of genetically encoded protein or peptide tag fused to the protein of interest (POI) and from a small fluorescent molecule which labels the POI-tag fusion. Particular representatives with their advantageous and disadvantageous properties are mentioned and super-resolution microscopy and calcium imaging, as applications of chemical tags, are explained. Experimental part is divided into chemical synthesis and biological methods. In synthetic part, four precursors of chemical tags have been prepared - two precursors of TMP-tag small molecule and two precursors of a chemical calcium dye. These precursors can be connected to create a new TMP-tag applicable for calcium imaging. One...
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Some aromatic sulphonamide inhibitors of carbonic anhydrase and their use in nuclear medicineSingh, J. January 1986 (has links)
No description available.
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Flourophore labelling of biopolymersGray, Robert A. January 1995 (has links)
No description available.
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Patient information and its influence on medication complianceRaynor, David Kenneth January 1991 (has links)
No description available.
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The development and application in immunogold labelling techniques of Mycoplasma iowae in turkeysShareef, J. M. January 1988 (has links)
No description available.
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Radiomarcacao de chrysomya megacephala (Fabricius, 1794) (Diptera, Calliphoridae) e criacao de Belonuchus rufipennis (Fabricius, 1801) (Coleoptera, Staphylinidae) em ovos desta moscaGARCIA, CRISALIDA R. 09 October 2014 (has links)
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Visual memory and spelling in 13 year oldsGiles, David Clifford January 1996 (has links)
No description available.
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Radiomarcacao de chrysomya megacephala (Fabricius, 1794) (Diptera, Calliphoridae) e criacao de Belonuchus rufipennis (Fabricius, 1801) (Coleoptera, Staphylinidae) em ovos desta moscaGARCIA, CRISALIDA R. 09 October 2014 (has links)
Made available in DSpace on 2014-10-09T12:37:35Z (GMT). No. of bitstreams: 0 / Made available in DSpace on 2014-10-09T14:03:17Z (GMT). No. of bitstreams: 1
05179.pdf: 1454166 bytes, checksum: 44fc64ae5011ac93aa9d3d7cfdb3f584 (MD5) / Tese (Doutoramento) / IPEN/T / Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
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Special education leavers in Central Scotland : A socio psychological perspectiveCheston, R. I. L. January 1988 (has links)
No description available.
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Ekologické aspekty označování výrobků / Ecologic aspects of product labellingMikešová, Veronika January 2009 (has links)
This thesis analyzes systems of product labeling. The aim is to assess the current state of the product labeling and may propose possible improvements. It brings a description and analysis carried out most of the current product labeling systems used in the Czech Republic. The conclusion provides an analysis of the labeling especially in ecological terms, as well as the shortcomings in the system of labeling, such as lack of propagation, lack of cooperation of providers brand and lack of cooperation of Ministry of the Environment with the providers and lack of standardization and fragmentation.
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