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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

All-digital Low-power PLL Circuit Design and Load Shift Keying Wireless Modulator Circuit Design for Implantable Biomedical SOC

Tseng, Sheng-lun 04 July 2006 (has links)
The first topic of this thesis is to propose a design of an all-digital low¡Vpower PLL (ADPLL). This design is implemented by only using standard cell library. The design cycle is effectively reduced. Furthermore, the portability and reusability of the proposed design is significantly raised. The large power consumption, glitch hazards, and timing violations of prior ADPLL designs are avoided by the proposed control method and modified DCO with multiplexers. The proposed design is implemented by only using the standard cell library of TSMC (Taiwan Semiconductor Manufacturing Company) 0.18 um 1P6M CMOS process. The feature of power saving is verified by measurement, which shows that the power consumption of the proposed ADPLL is merely 1.45 mW at 166 MHz output. The second topic of this thesis is a load shift keying wireless modulator circuit for implantable biomedical SOC. We successfully realize data and power transmission between outer controller and an implantable chip via wireless RF transmission interface. The convenience and the safety of using the implantable biomedical chip are significantly improved. The proposed on-chip LSK modulator consumes less power and area than those of traditional designs. Hence, the design margin of the implantable biomedical chip will be relaxed. The proposed LSK modulator is implemented with TSMC 0.35um 2P4M mixed-signal process. The proposed wireless RF transmission interface is implemented on PCB with discrete components.
2

Flagellin-Mediated Irradiation Protection in Mice

Oyewole-Said, Damilola 08 August 2017 (has links)
Bone marrow (BM) transfer from flagellin-treated mice has been reported to improve the survival of lethally-irradiated mice. Although the mechanism for flagellin’s antiviral and antibacterial effects have been elucidated, there remains a gap in knowledge regarding its radioprotective effects. Here, we report that flagellin treatment results in a 5-fold increase in the proliferation of Lin-Sca-1+C-Kit+(LSK) cells, a heterogeneous stem and multipotent cell population in BM, with the most striking increase within the ST-HSC, MPP2 and MPP3 subpopulations. Furthermore, the presence of TLR5 but not NLRC4 on radiosensitive, non-LSK cells in BM was both sufficient and necessary for the observed phenomenon. Finally, adoptive transfer of MPP3 cells along with an insufficient amount of whole bone marrow cells (WBM) to lethally-irradiated mice significantly improved their survival, recapitulating the effects of Whole bone marrow from flagellin-treated mice.
3

Regulation Of Hematopoietic Stem Cells By Lipid and Mitochondrial Metabolism

Sharma, Devyani 15 June 2020 (has links)
No description available.
4

Kalbos atpažinimo priemonių tyrimas / Research of speech recognition methods

Prokopovič, Valerij 15 June 2005 (has links)
Two speech recognition methods: Dynamic Time Warping and Hidden Markov model based methods were investigated in this work To estimate efficiency of the methods, speaker dependent and speaker independent isolated word recognition experiments were performed. During experimental research it was determined that Dynamic Time Warping method is suitable only for speaker dependent speech recognition. Hidden Markov model based method is suitable for both – speaker dependent and speaker independent speech recognition.
5

Wandlungen in der Steuerung des DDR-Hochleistungssports in den 1960er und 1970er Jahren

Ritter, Andreas January 2002 (has links)
Die intensive Auswertung unterschiedlicher schriftlicher und mündlicher Quellen sowie die Erschließung von damals "geheimer" Literatur für die Forschung heute ermöglicht eine differenzierte Rekonstruktion historischer Abläufe. Die vorliegende Arbeit nutzt diesen Zugang zur Darstellung von kleineren und größeren DDR-internen sportpolitischen Strukturwandlungen der 1960er und 1970er Jahre, die ihren Höhepunkt in einer dramatischen Umsteuerung des DDR-Hochleistungssports fanden.<br /> Es wird gezeigt, wie die Akteure unter Führung von Manfred EWALD, gewähltem Mitglied des SED-Zentralkomitees, einer Zentralfigur des DDR-Sports (vergleichbar mit der Bedeutung eines Willi DAUME im Westen) zwischen Systemzwängen und individueller Handlungsfreiheit innerhalb des Rahmens einer Diktatur in der Phase des Wechsels von Walter ULBRICHT zu Erich HONECKER eine Effektivierung des zentralistischen Modells durchsetzten (eine Parallele zum Ansatz von Monika KAISER).<br /> Im Gegensatz zu vielen kontroversen Erklärungsmodellen belegt der Verf., dass die Medaillenerfolge durch die zentrale Steuerung aller Abläufe gewährleistet wurden. Ohne SED-Auftrag wurde 1967 die "Leistungssportkommission der DDR" (LSK der DDR) gebildet. <br /> Im Unterschied zu den zahlreichen vom Verf. erstmals dargestellten Vorgängermodellen war diese SED-LSK "oberhalb des DTSB" angesiedelt und erteilte ihm Parteiaufträge - die Unterordnung des organisierten Sports unter die Autorität des Zentralkomitee machte angesichts der "Nationalen Fronten" von Armeesportvereinigung "Vorwärts" und Sportvereinigung "Dynamo" (SPITZER) jegliche zentrale Sportpolitik erst durchsetzbar.<br /> Zur "LSK der DDR" waren SED-Mitglieder abgeordnet, welche ihr Sachgebiet vertraten und nach gemeinsamer Beschlussfassung die Ergebnisse der LSK-Arbeit wiederum in ihrem jeweiligen Tätigkeitsfeld durchzusetzen hatten, was in der Diss. ausgeführt wird. Sportvertreter ebenso wie hochrangige Abgesandte der Ministerien, die mit der Produktion von Gütern für den Hochleistungssport befasst waren, gehörten den LSK-Gremien an, die auch die DDR-Sportwissenschaft steuerten; es lässt sich sogar nachweisen, dass die Herrschaft über diesen wichtigen Apparat sowie die Dopingforschung ein Hauptmotiv der LSK-Bildung gewesen ist.<br /> <br /> Durch seine Quellenorientierung und die Fülle an Belegen gibt die vorliegende Arbeit neue Anreize zur Auseinandersetzung mit dem Phänomen der Steuerung des Hochleistungssports in der DDR - auch über den Untersuchungszeitraum hinaus. <br /> Die Untersuchung wurde von der Humanwissenschaftlichen Fakultät der Universität Potsdam als Dissertation angenommen. Sie geht auf ein Stipendium dieser Universität zurück; das Verfahren konnte mit einem Prädikat abgeschlossen werden. Gutachter waren Prof. Dr. Dr. Gertrud PFISTER, Kopenhagen, Prof. Dr. Christoph KLEßMANN, Potsdam, und der Betreuer, Steady Visiting Prof. Univ. Odense, Priv.-Doz. Dr. habil. Giselher SPITZER, Berlin / Potsdam / Odense (Dänemark). / The guaranteed provision of material support for the athletes used to be a precondition for success in sports: 'Competitive sports under the conditions of the GDR' - thus the source material on this early model of professional sports. The author reveals both illegal (according to the IOC regulations) payments and a new drive towards success-oriented payments at least for the coaches. The latter trend was already the result of a dramatic change in competitive sports in the GDR. Today, a thorough analysis of contemporary documents, oral testimony, and formerly classified literature allows a more nuanced reconstruction of the historical events and processes. This work shows how the organisers of GDR sports, led by Manfred EWALD (EWALD was an elected member of the SED Central Committee and a central figure in the GDR sports scene. He might be characterised as the opposite number of Willi DAUME in the FRG.) succeeded with establishing a more efficient centralistic model (here, there is a parallel with Monika KAISER's approach). Despite the constraints of the system, they brought about his change at a time of political transition from Walter ULBRICHT to Erich HONECKER. <br /> In contrast to many other, controversial interpretations, the author argues that the athletic successes originated in the central organisation of GDR sports. In 1967, the 'Competitive Sports Commission of the GDR' (LSK) was established without explicit orders from the SED. In contrast to numerous older models, which the author has discovered, this new model was positioned 'above the DTSB' and gave party orders to the DTSB - the subordination of organised sports to the authority of the Central Committee allowed the implementation of a central sports policy. Given the 'National Fronts' of the Army Sports Club Vorwärts and the Sports Club Dynamo (SPITZER), this was an especially difficult task. The LSK was composed of members of the SED. After reaching an agreement on certain issues, every member had to implement the agreed policy in his or her specific field of activity, as this dissertation shows. The LSK subcommittees consisted of representatives of the sports as well as high-ranking representatives of those ministries which supervised the production of goods needed in competitive sports. It can be demonstrated, that control over this important body as well as the doping research was an important factor in the establishment of the LSK. <br /> <br /> The work on 'Changes in the control of competitive sports in the GDR in the 1960s and 1970s', brought the awarded degree of Doctor of Philosophy with distinction by the faculty of arts of the University of Potsdam to the author. The research was sponsored by the University of Potsdam. The degree committee consisted of Professor Gertrud PFISTER (Kopenhagen), Professor Christoph KLEßMANN (Potsdam), and the dissertation supervisor, Privatdozent Dr Giselher SPITZER (Berlin, Potsdam, Odense (Denmark)).

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