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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

AVALIAÇÃO DA ATIVIDADE ANGIOGÊNICA E DO POTENCIAL DE CICATRIZAÇÃO DO LÁTEX DE EUPHORBIA TIRUCALLI (AVELOZ)

Bessa, Guilherme de Oliveira 21 December 2010 (has links)
Made available in DSpace on 2016-08-10T10:53:30Z (GMT). No. of bitstreams: 1 GUILHERME DE OLIVEIRA BESSA.pdf: 720852 bytes, checksum: 2a03c7ad65ffe25ca5a6debf0d09987e (MD5) Previous issue date: 2010-12-21 / Through this research we aim to demonstrate the effectiveness of the latex of E. tirucalli in wound care as an adjunct in the healing process. The latex was obtained from a specimen plant in the city of Goiania, and diluted to the concentration of 1mg/mL. Two experiments were conducted using experimental models: the chorioallantoic membrane of embryonated chicken eggs and wounds in rats. In the first experiment, we evaluated the angiogenic response of the use of latex membranes, compared with controls. In the second one, sequential measurements were made of the wounds of rats, with regular use of the substance and controls until complete healing of the lesions. The results showed effective healing and angiogenic stimuli, similar to the positive control used (the latex of rubber tree). / Por meio deste trabalho, objetiva-se demonstrar a eficácia do látex de E. tirucalli no tratamento de feridas como adjuvante no processo cicatricial. O látex foi obtido de um exemplar da planta, na cidade de Goiânia, e diluído para a concentração de 1mg/mL. Foram realizados dois experimentos, utilizando como modelos experimentais a membrana corio-alantóide de ovos embrionados de galinhas e feridas em dorsos de ratos. No primeiro experimento, avaliou-se a resposta angiogênica do uso do látex nas membranas, comparando-se com controles. No segundo, foram feitas mensurações seqüenciais dos ferimentos dos ratos, com o uso regular da substância e controles, até a cicatrização completa das lesões. Os resultados revelaram estímulos angiogênico e cicatricial efetivos, semelhantes ao controle positivo utilizado (a biomembrana de látex de seringueira).

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