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Sample comparisons using microarrays: - Application of False Discovery Rate and quadratic logistic regressionGuo, Ruijuan 08 January 2008 (has links)
In microarray analysis, people are interested in those features that have different characters in diseased samples compared to normal samples. The usual p-value method of selecting significant genes either gives too many false positives or cannot detect all the significant features. The False Discovery Rate (FDR) method controls false positives and at the same time selects significant features. We introduced Benjamini's method and Storey's method to control FDR, applied the two methods to human Meningioma data. We found that Benjamini's method is more conservative and that, after the number of the tests exceeds a threshold, increase in number of tests will lead to decrease in number of significant genes. In the second chapter, we investigate ways to search interesting gene expressions that cannot be detected by linear models as t-test or ANOVA. We propose a novel approach to use quadratic logistic regression to detect genes in Meningioma data that have non-linear relationship within phenotypes. By using quadratic logistic regression, we can find genes whose expression correlates to their phenotypes both linearly and quadratically. Whether these genes have clinical significant is a very interesting question, since these genes most likely be neglected by traditional linear approach.
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Analys av bortfall i en uppföljningsundersökning av hälsa / Analysis of attrition in a longitudinal health studyUdd, Mattias, Pettersson, Niklas January 2008 (has links)
The LSH-study started in 2003 at the department of Health and Society at the University of Linköping. The purpose of the study was to examine the relationship between life condition, stress and health. A total of 1007 people from ten different health centres in Östergötlands län participated. At the follow up, a couple of years later, 795 of the 1007 participated. 127 of the 212 in the attrition turned down the follow up, twelve people were not invited (for example in case of death) and the rest did not respond at all. The purpose of this paper is to find out in what degree the attrition in the follow up can be predicted using the information from the first survey and which variables are important. The differences between different types of attrition have also been examined. Simple and multiple bi- and multinomial logistic regression have been used in the analysis. In total 34 variables were examined and in the final model six variables remained with a significant relation to the attrition. High BMI, regular smoking, high pulse and lack of daily exercise at the first survey were connected to a higher risk for an individual to not participate at the follow up. It is interesting that these factors are considered as risk factors for unhealthy living. Other factors related to a higher attrition were unemployment in the last year before the first survey and if the individual had parents born in another country than Sweden. The risk for attrition increased gradually when more risk factors were shown by the individual. The factors contributing an individual to turn down the follow up instead of not responding at all was if he or she were in the older age segments in the survey or if they were not active in any type of association.
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Analys av bortfall i en uppföljningsundersökning av hälsa / Analysis of attrition in a longitudinal health studyUdd, Mattias, Pettersson, Niklas January 2008 (has links)
<p>The LSH-study started in 2003 at the department of Health and Society at the University of Linköping. The purpose of the study was to examine the relationship between life condition, stress and health. A total of 1007 people from ten different health centres in Östergötlands län participated. At the follow up, a couple of years later, 795 of the 1007 participated. 127 of the 212 in the attrition turned down the follow up, twelve people were not invited (for example in case of death) and the rest did not respond at all. The purpose of this paper is to find out in what degree the attrition in the follow up can be predicted using the information from the first survey and which variables are important. The differences between different types of attrition have also been examined. Simple and multiple bi- and multinomial logistic regression have been used in the analysis.</p><p>In total 34 variables were examined and in the final model six variables remained with a significant relation to the attrition. High BMI, regular smoking, high pulse and lack of daily exercise at the first survey were connected to a higher risk for an individual to not participate at the follow up. It is interesting that these factors are considered as risk factors for unhealthy living. Other factors related to a higher attrition were unemployment in the last year before the first survey and if the individual had parents born in another country than Sweden. The risk for attrition increased gradually when more risk factors were shown by the individual. The factors contributing an individual to turn down the follow up instead of not responding at all was if he or she were in the older age segments in the survey or if they were not active in any type of association.</p>
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An ordinal logistic regression model with misclassification of the outcome variable and categorical covariate.Shirkey, Beverly Ann. Waring, Stephen Clay, January 2009 (has links)
Source: Dissertation Abstracts International, Volume: 70-03, Section: B, page: 1743. Advisers: Wenyaw Chan; Glasser H. Jay. Includes bibliographical references.
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A Comparison Of Remedy Methods For Logistic Regression When Data Are CollinearJanuary 2016 (has links)
Heng Wang
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Modeling the NCAA Tournament Through Bayesian Logistic RegressionNelson, Bryan 18 July 2012 (has links)
Many rating systems exist that order the Division I teams in Men's College Basketball that compete in the NCAA Tournament, such as seeding teams on an S-curve, and the Pomeroy and Sagarin ratings, simplifying the process of choosing winners to a comparison of two numbers. Rather than creating a rating system, we analyze each matchup by using the difference between the teams' individual regular season statistics as the independent variables. We use an MCMC approach and logistic regression along with several model selection techniques to arrive at models for predicting the winner of each game. When given the 63 actual games in the 2012 tournament, eight of our models performed as well as Pomeroy's rating system and four did as well as Sagarin's rating system when given the 63 actual games. Not allowing the models to fix their mistakes resulted in only one model outperforming both Pomeroy and Sagarin's systems. / McAnulty College and Graduate School of Liberal Arts / Computational Mathematics / MS / Thesis
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Topics in ordinal logistic regression and its applicationsKim, Hyun Sun 15 November 2004 (has links)
Sample size calculation methods for ordinal logistic regression are proposed to test statistical hypotheses. The author was motivated to do this work by the need for statistical analysis of the red imported fire ants data. The proposed methods use the concept of approximation by the moment-generating function. Some correction methods are also suggested. When a prior data set is available, an empirical method is explored. Application of the proposed methodology to the fire ant mating flight data is demonstrated. The proposed sample size and power calculation methods are applied in the hypothesis testing problems. Simulation studies are also conducted to illustrate their performance and to compare them with existing methods.
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Logistic Service Development of E-commerce : A case study of AliExpress - an online international trade platform in ChinaGong, Wei, Kan, Xuan January 2013 (has links)
Background: as a convergence of business activities and information technology, e-commerce has brought massive changes to the supply chain management. Today, many e-commerce companies choose to cooperate with third party logistic service providers to perform or improve their logistic services. Meanwhile, those e-commerce companies con-sistently affect the operational processes of their logistic service providers. This thesis fo-cuses on the case of AliExpress, which is an e-commerce company that collaborates with third party logistics in terms of their transportation, warehousing, etc. The collaborations have evolved through time, and developed by three stages, each of which aims at having better logistic performances to generate more profits. Aim and purpose: the aim of this research is to analyse the development of logistic ser-vices for e-commerce by partnering with third party logistic service providers in the setting of international trade. By studying the development, the benefits will be identified. Method: the authors used inductive approach to fulfil the exploratory purposes. In order to gather primary data, the authors applied interviews. Company documents, journal papers, articles and books were collected as secondary data respectively. Result and analysis: the authors obtained empirical findings from three interviews. In the findings, the authors depicted the process of logistic service development and comparisons between logistic service development benefits for e-commerce and sellers have been made. In terms of data analysis, the authors used the theoretical framework in conjunction with the findings to answer the research questions. Conclusion: in the final chapter, the authors answered the research questions based on the analysis. The authors conclude that logistic service development for e-commerce has three stages which are: partner with 3PL, work towards channel collaboration and build an e-fulfilment strategy. The benefits of such development are equitable and shared for both e-commerce company and sellers.
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Factors Affect the Employment of Youth in ChinaLi, Xiaoxue January 2009 (has links)
Today's young people are well-educated ever but in a poor employment situation. At the beginning of this paper, I first state the situation both in the world and in China, revealing the poor employment situation of youth. Then I introduce systems related to youth employment in China and measures the government taken to help graduate students to find a job. The purpose of this paper is to analyze employment of youth people in China especially among the medium and highly educated people and find which and how the factors contribute to it. By using the Logistic Regression by STATA, I find that the main factors are gender, age, living area, and political status, major and educational level. The result reveals that the discrimination and gap between rural and urban area are severe issues in China. Last but not least, I give some suggestions both to the society and the individual to improve the youth employment.
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Modeling and characterization of potato quality by active thermographySun, Chih-Chen 15 May 2009 (has links)
This research focuses on characterizing a potato with extra sugar content and identifying the location and depth of the extra sugar content using the active thermography imaging technique. The extra sugar content of the potato is an important problem for potato growers and potato chip manufacturers. Extra sugar content could result in diseases or wounds in the potato tuber. In general, potato tubers with low sugar content are considered as having a higher quality.
The inspection system and general methodologies characterizing extra sugar content will be presented in this study. The average heating rate obtained from the thermal image analysis is the major factor in characterization procedures. Using information on the average heating rate, the probability of achieving a potato with extra sugar content may be predicted using the logistic regression model. In addition, neural networks are also used to identify the potato with extra sugar contents. The correct rate for identifying a potato with extra sugar content in it can reach 85%. The location of extra sugar content can also be found using the logistic regression model. Results show the overall correct rate predicting the extra sugar content location with a resolution of 20 by 20 pixels is 91%. In predicting the extra sugar content depth, amounts exceeds 2/3 inches are not detectable by analyzing thermal images. The depth of extra sugar content can be discriminated in 0.3 inch increments with a high rate of accuracy (87.5%).
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