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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Statistical issues in the analysis of the DNA microarray data: Normalization and differential expression /

Xiao, Yuanyuan. January 2004 (has links)
Thesis (Ph.D.)--University of California, San Francisco, 2004. / Bibliography: leaves 92-101. Also available online.
2

Statistical design and analysis of microarray experiments

Wang, Tao. January 2005 (has links)
Thesis (Ph. D.)--Ohio State University, 2005. / Title from first page of PDF file. Document formatted into pages; contains ix, 146 p.; also includes graphics (some col.) Includes bibliographical references (p. 145-146). Available online via OhioLINK's ETD Center
3

An integrated framework for feature selection and classification in microarray data analysis

Leung, Yuk-yee. January 2009 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 120-132). Also available in print.
4

Computational methods for microarray gene expression analysis through integration and knowledge discovery a thesis submitted to Auckland University of Technology in partial fulfillment of the degree of Doctor of Philosophy, 2005.

Goh, Liang. January 2005 (has links) (PDF)
Thesis (PhD) -- Auckland University of Technology, 2005. / Also held in print (267 leaves : col. ill. ; 30 cm.) in City Campus Theses Collection. (T 572.8636 GOH)
5

An integrated framework for feature selection and classification in microarray data analysis

Leung, Yuk-yee., 梁玉儀. January 2009 (has links)
published_or_final_version / Electrical and Electronic Engineering / Doctoral / Doctor of Philosophy
6

Thermodynamic Effects of 5' and 3' Single Strand Dangling Ends on Short Duplex DNA

Dickman, Rebekah 01 January 2010 (has links)
Differential scanning calorimetry (DSC) melting analysis was performed on 27 short double stranded DNA duplexes containing 15 to 25 base pairs and short single stranded overhangs from one to 10 bases, on both ends. Molecules have two 5' dangling ends or one 5' and one 3' dangling end. For these molecules the duplex region was incrementally reduced from 25 to 15 base pairs with increased length of the dangling ends from one to 10 bases. A third set of molecules contained 21 base pair duplexes with a four base dangling end on either the 5' or 3' end. Blunt ended duplexes from 15 to 25 base pairs were also examined and served as control duplexes. DSC melting curves were measured in solution containing 85 mM, 300 mM or 1.0 M Na+. From these measurements, thermodynamic parameters for 5' and 3' dangling ends as a function of end length were evaluated. Results showed the 5' ends were slightly stabilizing, and this stability was essentially constant with end length, while the 3' ends were generally destabilizing with increasing length of the end. This finding of lower stability for the 3' ends is consistent with results of published studies that have found 5' dangling ends to be more than or equally as stabilizing as 3' dangling ends. Our finding that 3' dangling ends are actually destabilizing for duplex DNA contrasts with published results. The 3' ends also display a stronger dependence on the [Na+]. In the lower Na+ environment the 3' ends are more destabilizing than at the higher salt environments. Analysis of the thermodynamic parameters of the dangling-ended duplexes as a function [Na+] indicated the 3' dangling end molecules behave differently compared to 5' dangling ended and blunt ended duplexes. The net counterion release per phosphate upon melting the molecules having one 5' and one 3' end was approximately 15% smaller as a function of end length compared to the duplex having two 5' ends. Further analysis of the DSC evaluated thermodynamic transition parameter, ΔHcal, and its relationship to the measured transition temperatures of the DNA molecules, provided an estimate on the excess heat capacity differences, ΔCp, between duplex and melted single strands for the dangling-ended molecules. The analysis revealed the molecules with one 5' and one 3' dangling end had very different ΔCp values compared to the blunt-ended molecule; while the molecules with two 5' ends have ΔCp that are essentially the same as the blunt-ended duplex. These observations are interpreted as differences in the interactions with Na+, solvent and the terminal base pairs of the duplex for the 5' versus 3' dangling ends.
7

A novel probabilistic framework for microarray data analysis from fundamental probability models to experimental validation /

Gelmi, Claudio A. January 2007 (has links)
Thesis (Ph.D.)--University of Delaware, 2006. / Principal faculty advisors: Babatunde Ogunnaike and Jeremy S. Edwards, Dept. of Chemical Engineering. Includes bibliographical references.
8

Molecular characterization of IBDV-induced apoptosis in vitro using cDNA microarrays

Wong, Tsz-yeung. January 2005 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2006. / Title proper from title frame. Also available in printed format.
9

Microarray bioinformatics and applications in oncology

Peeters, Justine Kate, January 2008 (has links)
Thesis Erasmus University Rotterdam. / ook verschenen in gedrukte versie. With bibliogr., with a summary in Dutch.
10

Automation of comparative genomic promoter analysis of DNA microarray datasets

Karanam, Suresh Kumar, January 2003 (has links) (PDF)
Thesis (M.S. in App. Bio.)--School of Biology, Georgia Institute of Technology, 2004. Directed by Roger M. Wartell. / Includes bibliographical references (leaves 34-37).

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