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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
21

Clustering analysis of microarray gene expression data /

Szeto, Lap Keung. January 2005 (has links) (PDF)
Thesis (M.Phil.)--City University of Hong Kong, 2005. / "Submitted to Department of Computer Engineering and Information Technology in partial fulfillment of the requirements for the degree of Master of Philosophy" Includes bibliographical references (leaves 70-79)
22

Tool for the identification of differentially expressed genes using a user-defined threshold /

Alleyne, Renikko. January 2006 (has links)
Thesis (M.S.)--Rochester Institute of Technology, 2006. / Typescript. Includes bibliographical references (leaf 58).
23

Design and development of oligonucleotide microarrays and their application in diagnostic and prognostic estimation of human gliomas

Taylor, G. Scott. January 1900 (has links)
Thesis (Ph.D.) -- Virginia Commonwealth University, 2006. / Thesis lacks signature page. Title from title-page of electronic thesis. Prepared for: Dept. of Chemical Engineering. Bibliography: p. 99-113.
24

Projected clustering and pooling designs /

Deng, Ping, January 2007 (has links)
Thesis (Ph.D.)-- University of Texas at Dallas, 2007. / Includes vita. Includes bibliographical references (leaves 76-81)
25

A finite element study of the DNA hybridization kinetics on the surface of microfluidic devices

Pascault, Jean-Roland Eric. January 2007 (has links)
Thesis (M.S.) -- Worcester Polytechnic Institute. / Keywords: DNA; hybridization; microfluidics; kinetics. Includes bibliographical references (leaves 145-148).
26

The development of a microbead array for the detection and amplification of nucleic acids

Ali, Mehnaaz Fatima, January 1900 (has links) (PDF)
Thesis (Ph. D.)--University of Texas at Austin, 2006. / Vita. Includes bibliographical references.
27

Effect of probe-target sequence mismatches on the results of microarray hybridisations : position-dependence, modelling and impact of evolutionary distance

Tate, Catriona Mary January 2010 (has links)
No description available.
28

Bioinformatic analyses of microarray experiments on genetic control of gene expression level

Kirk, Michael, School of Biotechnology & Biomolecular Science, UNSW January 2006 (has links)
The advent of microarray technology, allowing measurement of gene expression levels for thousands of genes in parallel, has made possible experiments designed to investigate the genetic control of variation in gene expression level (described in the literature as ???genetical genomics??? or ???eQTL??? experiments). Published results from these studies, in yeast and in mice, show that genetic variation is an important factor in gene regulation, and furthermore that individual polymorphisms modify the expression level of many genes. The concern of this thesis is the bioinformatic analyses of the expression level and genotype data sets that are the raw material for these studies. In particular this thesis addresses the two issues of detection of artefactual effects, and maximizing the information that can be extracted from the data. It is shown that while a polymorphism affecting the expression of many genes may be readily detected, care must be taken to determine whether the detected effect is genuinely one of genetic control of expression level, rather than the effect of correlations in measured expression level not of genetic cause. A significance test is devised to distinguish between these cases. The detection of artefactual correlation is explored further in the reanalysis of the published data from a large yeast study. A critique is given of the permutation method used to ascribe genetic control as the cause of inter gene expression level correlation. The presence of some degree of artefactual correlation is shown, and novel methods are presented for identifying such artefacts. To extend the analyses that may be applied to eQTL data, an algorithm is presented for determining secondary eQTLs for gene expression level (as opposed to a single primary QTL), along with a significance test for the putative QTL found. The technique is demonstrated on a large public data set. In addition to the use for which they are intended, the data sets generated for eQTL studies provide opportunities for additional analyses. In this thesis a method is developed for calculating a genome wide map of meiotic recombination frequency from the genotype data for multiple segregant strains. The method is demonstrated on the published genotype data generated for a large yeast eQTL study.
29

Molecular detection and identification of avian influenza viruses by cDNA microarray

Maughan, Michele Nancy. January 2007 (has links)
Thesis (M.S.)--University of Delaware, 2006. / Principal faculty advisor: Calvin L. Keeler, Dept. of Animal & Food Sciences. Includes bibliographical references.
30

Automation of comparative genomic promoter analysis of DNA microarray datasets

Karanam, Suresh Kumar 01 December 2003 (has links)
No description available.

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