Lymphoedema is a chronic health condition characterized by the accumulation of lymphatic fluid in the subcutaneous tissues resulting in arm swelling and can significantly affect physical and psychological health and QOL. Although significant research on lymphoedema has developed over the past decade, the literature reveals that there are gaps in knowledge on framing the illness, communication, and effective practices to improve the QOL for individuals living with lymphoedema. This research contributes to this growing field of research through a qualitative investigation of twelve women's reported understandings, experiences, and perceptions of lymphoedema using Brown’s (1995) theory of framing disease and illness. Semi-structured interviews were conducted with women living with lymphoedema to determine the impact of health messaging, to explore the ways in which these women made sense of conflicting messages on exercise, and to better understand how barriers to the effective adoption and integration of good management practices can be overcome.

Improvements in the treatment of breast cancer have resulted in better survival rates and less breast cancer related morbidity. Nevertheless, a significant group of patients still experience a diminished quality of life as a result of lymphedema. In the early, often reversible, stage of lymphedema patients can experience subjective changes in the affected area. However, with the traditionally available tools the lymphedema often remains clinically undetectable and patients are denied essential care that can prevent worsening. Furthermore, most lymphedema assessment tools fail to support a clear unambiguous definition of lymphedema. This underlines the need for a sensitive objective measurement method that can assess lymphedema in a subclinical stage. In this study we demonstrated that measuring tissue dielectric constant (TDC) using the MoistureMeter-D is an effective method to detect tissue water changes and could potentially provide a cost-effective adequate tool to measure the early onset of breast cancer related lymphedema (BCRL). Secondarily, we established the correlation between the novel TDC method and the frequently used arm volume measurements and self-assessment questionnaires. A group of 20 female patients with clinically BCRL were included. TDC measurements in both arms and all quadrant of both breast were recorded along with volumetric measurements of both arms. All patients were asked to complete a self-report questionnaire. The novel TDC method detected significantly higher tissue water levels in the affected arm and breast compared to the control side. The TDC ratio between control and affected side showed significant correlation with self-reported pain and discomfort in both arm and breast. In the arm, the TDC method also showed correlation with the volume measurement method. The TDC value of the arm was correlated to age, but not to BMI. This study demonstrates that measuring TDC using the MMD is an effective method for quantifying lymphedema in arm and breast and is an important tool in detecting early TWC changes.

Made available in DSpace on 2016-08-03T16:34:37Z (GMT). No. of bitstreams: 1 FABIA CRISTINA ACEGRANCE.pdf: 676682 bytes, checksum: b15d40fc083b3726c33be800be16866c (MD5) Previous issue date: 2007-02-13 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Arm lymphoedema is an inherent complication of the breast cancer treatment. Characterized by the increase of the arm volume, it leads to the physical and functional limitations, and negative impact in the psychological and social scope. The aim of this study was to investigate the quality of life and its domains, the coping strategies front to the breast cancer, and the correlation between these variables. This study was carried through in a health women center, for four months. The evaluation instruments were: general and specific characterization questionnaire of the breast cancer, arms circumference measurements; quality of life questionnaires of the European Organization for Research and Treatment of Cancer , EORTC QLQ-30 and BR-23; and the Coping Strategies Inventory. Totally, 82 women had been interviewed, 57,4 mean age (SD 12,3), submitted unilateral breast surgical treatment or axillary lymph node dissection, without metastasis. The lymphoedema was presented in 39.03% (32) presented lymphoedema. Lymphoedema seems not interfered on the breast cancer iwomen quality of life, harming more the social function. Chemotherapy and the breast symptoms related bother the women of both groups, however the arms symptoms were statistically significant bigger in the lymphoedema s women. The strategies more used by the interviewed to face the breast cancer were: positive reappraisal, planful problem solving, escape/avoidance, social support and self-controlling, the self-controllling was only statistically bigger in the lymphoedema s women. The planful problem solving strategies, self-controlling and low social support can have collaborated for the developed of lymphoedema. None high correlation was found between variables analyzed. Concludes that the use of active and positive strategies to face the breast cancer seems to result in a good psicossocial adaptation / O linfedema no membro superior é uma complicação inerente ao tratamento de câncer de mama. Caracterizado pelo aumento do volume do membro, leva às limitações físicas e funcionais, e impacto negativo no âmbito psicológico e social. O objetivo deste estudo foi investigar a qualidade de vida e seus domínios, as estratégias de enfrentamento frente ao câncer de mama, e a correlação entre essas variáveis. Este estudo foi realizado em um centro de saúde dedicado às mulheres, por quatro meses. Os instrumentos de avaliação foram: questionário de caracterização geral e específico do câncer de mama, perimetria dos membros superiores; questionários de qualidade de vida da Organização Européia de Pesquisa e Tratamento do Câncer, EORTC QLQ-30 e BR-23; e Inventário de Estratégias de Coping. Foram entrevistadas 82 mulheres, idade média de 57,4 anos (DV12,3), submetidas a tratamento cirúrgico de mama unilateral e esvaziamento axilar, sem metástase. O linfedema apresentou-se em 39,03% (32) e parece não interferir muito na qualidade de vida das mulheres pós-câncer de mama, sendo a função social a mais prejudicada. Sintomas relacionados à quimioterapia e a mama incomodam as mulheres de ambos grupos, porém os sintomas relacionados aos braços foram estatisticamente maiores nas portadoras de linfedema. As estratégias mais utilizadas pelas entrevistadas para enfrentar o câncer foram a reavaliação, resolução de problemas, fuga, suporte social e autocontrole, somente o autocontrole foi estatisticamente maior nas mulheres com linfedema. As estratégias de resolução de problemas, autocontrole e baixo suporte social podem ter colaborado para o desencadeamento do linfedema. Conclui-se que o uso de estratégias ativas e positivas para enfrentar o câncer de mama parece resultar na boa adaptação psicossocial

No / Objective To compare the incidence of treatment-related complications, including lymphoedema, after two programmes of shoulder mobilisation in women with invasive breast cancer when surgical treatment included axillary lymph node dissection. Design Randomised controlled trial. Setting Two secondary care National Health Service trusts. Participants One hundred and sixteen women (mean age 57 years, standard deviation 13.1 years) recruited from November 2003 to March 2006 (58 intervention group, 58 control group). Seven patients (6%) did not complete the study. Intervention Arm exercises and shoulder movement restricted to below shoulder level for the first 7 days after surgery. Controls commenced an exercise programme that incorporated exercises above shoulder level within 48 hours. Outcome measures All outcomes were recorded at baseline (pre-operatively) and at 1 year. The primary outcome was incidence of lymphoedema, defined by a limb volume difference of 200 ml or more compared with the contralateral arm. This outcome was measured using volume displacement. Secondary outcome measures included volume differences between the two limbs measured by actual volume displacement difference, wound drainage volumes, range of shoulder movement (manual goniometer), grip strength (hand-held dynamometer) and health-related quality of life (Shoulder Disability Questionnaire, Functional Assessment of Cancer Therapy – Breast). Results All statistical tests were two-sided. Data were analysed using intention-to-treat principles. The incidence of lymphoedema (200 ml or more) increased significantly in women who had undertaken a programme of early full shoulder mobilisation. Twenty-two women (19%) developed lymphoedema (200 ml or more) in their first postoperative year. There were significantly more women with lymphoedema in the early full shoulder mobilisation group (n = 16) compared with the delayed full shoulder mobilisation group (n = 6). The relative risk of developing lymphoedema after early mobilisation was 2.7 (95% confidence interval 1.1 to 6.3; P = 0.031). Limb volume differences were significantly higher in the early mobilisation group. This was apparent in differences in limb volume displacement (P = 0.004) and percentage difference between the two limbs (P = 0.007). There were no statistically significant differences in shoulder movement, grip strength or self-evaluated outcomes between the two groups at 1 year. Conclusion A programme of exercise that delays full shoulder mobilisation for 1 week is recommended after axillary node dissection for invasive breast cancer.