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Circulating tumor markers in extranodal lymphomas. / CUHK electronic theses & dissertations collectionJanuary 2002 (has links)
Lei Ieng Kit Kenny. / "April 2002." / Thesis (M.D.)--Chinese University of Hong Kong, 2002. / Includes bibliographical references (p. 89-118). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web.
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Clonal rearrangement of T-cell receptor delta gene in hematological malignancies and applications in detection of minimal residualdisease陳衛, Chan, Wai. January 1995 (has links)
published_or_final_version / Medicine / Master / Master of Philosophy
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Burkitt Lymphoma: Interpreting FISH Testing for Gene RearrangementsSharma, Purva, Singal, Sakshi, Costello, Patrick, Krishnan, Koyamangalath 08 February 2022 (has links)
Burkitt lymphoma is a highly aggressive B cell non-Hodgkin's lymphoma characterised by translocation of gene on chromosome 8. This translocation is usually detected by fluorescent in-situ hybridisation (FISH) studies as part of routine diagnostic work-up and prognostication. FISH testing is commonly done with the break-apart probe (BAP). This case illustrates how this testing can be falsely negative. This patient is a young male diagnosed with Stage I low-risk Burkitt with FISH negative for translocation initially on BAP testing. Additional testing with dual FISH probe detected translocation. FISH testing using BAPs alone may be falsely negative for translocations creating a diagnostic challenge and compromising the treatment approach and assessment of prognosis.
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