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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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シアノバクテリアにおける高頻度なin vivoのトランスポゾンタギング系の開発およびその系を利用したChl dを利用するシアノバクテリア、Acaryochloris marinaにおける順遺伝学的解析の確立 / Development of a high-frequency in vivo transposon mutagenesis system for cyanobacteria and establishment of the forward genetic analysis of the Chl d-dominated cyanobacterium, Acaryochloris marina by use of the system渡部, 和幸 23 March 2015 (has links)
Kyoto University (京都大学) / 0048 / 新制・課程博士 / 博士(人間・環境学) / 甲第19069号 / 人博第722号 / 新制||人||173 / 32020 / 京都大学大学院人間・環境学研究科相関環境学専攻 / (主査)准教授 土屋 徹, 教授 宮下 英明, 教授 川本 卓男 / 学位規則第4条第1項該当
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Development of a high-frequency in vivo transposon mutagenesis system for cyanobacteria and establishment of the forward genetic analysis of the Chl d-dominated cyanobacterium, Acaryochloris marina by use of the system / シアノバクテリアにおける高頻度なin vivoのトランスポゾンタギング系の開発およびその系を利用したChl dを利用するシアノバクテリア、Acaryochloris marinaにおける順遺伝学的解析の確立Watabe, Kazuyuki 23 March 2015 (has links)
京都大学 / 0048 / 新制・課程博士 / 博士(人間・環境学) / 甲第19069号 / 人博第722号 / 新制||人||173(附属図書館) / 26||人博||722(吉田南総合図書館) / 32020 / 京都大学大学院人間・環境学研究科相関環境学専攻 / (主査)准教授 土屋 徹, 教授 宮下 英明, 教授 川本 卓男 / 学位規則第4条第1項該当 / Doctor of Human and Environmental Studies / Kyoto University / DFAM
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Growth Dynamics, Antibiotic Susceptibility and the Effect of Sublethal Ciprofloxacin Concentrations in Susceptible and Resistant Escherichia coli in Biofilm / Tillväxtdynamik, Antibiotikakänslighet och Effekten av Subletala Koncentrationer av Ciprofloxacin på Känsliga och Resistenta Escherichia coli i BiofilmFernberg, Jenny January 2019 (has links)
Instead of planktonic growth in nature, many species of bacteria form biofilm to survive in harsh conditions. Although many chronic bacterial infections are caused by bacterial species in a biofilm lifestyle, previous research has focused on studying antibiotic resistance in planktonic growth. Here we used a modified MBEC assay, i.e. biofilm growth on pegs, to determine Escherichia coli biofilm inhibitory concentrations (BIC) of ciprofloxacin, streptomycin and rifampicin and to study the minimal selective concentration (MSC) for ciprofloxacin in E. coli biofilm. We could observe high inhibitory concentrations for all antibiotics in the biofilm pre-formed in media without antibiotics compared to the biofilm formed in antibiotics. We also show preliminary result indicating that sublethal concentrations of ciprofloxacin lead to the selection of ciprofloxacin resistant mutants in biofilm and that the selection level is lower than what was observed in planktonic growing E. coli. With more knowledge in how the biofilm formation precedes in different antibiotic settings, the treatment for chronic biofilm infections used today could be evaluated and changed so that the infections could be eradicated.
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