Despite numerous frameworks and models proposed in the literature, Information Systems (IS) assessment still remains elusive. In addition, little agreement exists on the contribution of the IS function within an organization and on how IS is related to the other organizational dimensions. Frameworks that show the relationship between IS and the organization are in the developmental stage and this work proposes a more comprehensive framework to assist in better understanding the relationship between IS and organizational quality. This research examines two popular IS quality assessment frameworks - Malcolm Baldrige National Quality Award (MBNQA) and Information Systems Assessment (ISA) - and suggests a new framework, IS-MBNQA. This work integrates these two IS quality assessment frameworks into a single comprehensive model that provides a holistic view on how IS quality is interrelated to organizational quality. The existing two IS assessment frameworks attempted to measure IS quality at different levels within an organization. The MBNQA model is the most comprehensive quality framework because it takes an organization wide perspective. On the other hand, ISA employs an IS specific perspective and reflects the relationships of eight major IS success dimensions. ISA is a modified version of DeLone & McLean's model with the inclusion of a success factor for Service Quality. For this study, survey instruments are developed from the MBNQA and ISA frameworks and they are consolidated to allow testing of the single IS-MBNQA framework. Exploratory factor analysis is performed for instrument refinement and confirmatory factor analysis for validity of the models. The instruments developed in this work are utilized as a foundation for identifying the relationships among the dimensions within and between each model. A major contribution of this work is the validation of the 2000 MBNQA model and the extension of existing models/frameworks to better explain the IS contribution to an organization.