MIV/VIGS is 'n mediese toestand wat verreikende gevolge vir die individu en sy omgewing inhou. Dit het 'n direkte fisiologiese impak, asook diverse psigososiale en neurologiese gevolge op die persoon (Lowenthal, 1997). Die mees algemene enkele neurologiese komplikasie van VIGS staan bekend as VIGS-demensiekompleks (VDK) (Cournos&Bakalar, 1999). VDK word gekenmerk deur kognitiewe en motoriese disfunksie sowel as gedragsveranderinge en gemoedsversteurings of affekversteurings in verskillende grade (Price, 1996). Ten spyte van die waardevolle literatuur reeds beskikbaar oor die neurologiese, kognitiewe, motoriese en psigologiese impak van VDK, is daar steeds beperkte data oor die gevolglike invloed daarvan op kommunikasievaardighede en die individu se ervaring daarvan (Zuniga, 1999). Om hierdie rede blyk daar 'n gaping te wees in die effektiewe doelgerigte behandeling van hierdie afwyking (Druck, 2002). Die doel van hierdie studie is om ondersoek in te stel na die individu met VDK se subjektiewe siekte-ervaring met betrekking tot moontlike kommunikasiepatologie, sowel as om die rol van die spraak-taalterapeut met betrekking tot individue met VDK te definieer. Daar is van 'n enkelgevallestudie, nie-eksperimentele, beskrywende opnameontwerp gebruik gemaak. Die navorsingsdeelnemer se narratiewe is ontlok deur middel van natuurlike gesprekvoering en 'n oudiobandopname is daarvan gemaak. Die narratief is getranskribeer en die volgende drie metodes is gebruik om dit volledig en omvattend te analiseer: 1.)Plotanalise, 2.) Strukturele storie-analise volgens Labov (1982) se strukturele benadering, en 3.) Holistiese inhoudsanalise. Uit die plotanalise het dit duidelik geword dat die betrokke narratief regessief van aard is. Tydens die bespreking van die meta-narratiewe het verskeie aspekte van hierdie individu met VDK se persoonlike siekte-ervaring na vore gekom wat betref die invloed daarvan op haar vermoë om steeds haar lewenskwaliteit te handhaaf deur aan haar alledaagse lewensaktiwiteite te kan deelneem. Die ICFkomponente is as raamwerk gebruik om die verkreë inligting op 'n sinvolle wyse voor te stel. Dit wil verder voorkom of die siekte-ervaring nie tot spesifieke aspekte van menslike funksionering, onder andere kommunikasiefunksies, beperk kan word nie. Die ervaring van haar kommunikasieprobleme maak deel uit van haar algehele siekte-ervaring wat binne die konteks van haar alledaagse lewensaktiwiteite en deelname daarin plaasvind. Die identifikasie en analise van die temas het dit verder duidelik gemaak dat narratiewe 'n effektiewe metode is om insig te verkry in die individu met VDK se konteks en ervaring daarvan. 'n Geheelbeeld van die individu se funksionele vaardighede, konteks en emosionele ervarings en behoeftes is verkry, sonder om haar bloot te stel aan formele toeste en evalueringsinstrumente wat haar onbevoeg en minderwaardig kan laat voel. Die verkreë resultate impliseer ook dat die individu met VDK se siekte-ervaring sentraal is tot sy of haar mate van deelname aan alledaagse lewensaktiwiteite asook ervaring van kwaliteit van lewe. Die waarde van narratiewe in die terapeutiese behandelingsproses het ook in hierdie studie duidelik geword. Narratiewe kan suksesvol aangewend word om 'n verbeterde insig in die individu met VDK se lewe en behoeftes te verkry. ENGLISH : HIV/AIDS is a medical condition that has far-reaching consequences for the individual and his or her environment. It has a direct physiological impact, as well as diverse psychological and neurological effects on the individual (Lowenthal, 1997). The most common single neurological complication of AIDS is known as AIDS Dementia Complex (ADC) (Cournos&Bakalar, 1999). ADC is associated with cognitive and motor dysfunction as well as behavioural changes and mood disorders of different degrees (Price, 1996). Despite all the valuable literature already available on the neurological, cognitive, motor and psychological impact of ADC, there is still limited data on the consequential influence thereof on the communication skills and the individual's experience and treatment of this (Zuniga, 1999). Therefore there seems to be a gap in the effective goal-directed treatment of this disorder. (Druck, 2002). The aim of this study is to investigate the subjective illness experience of the individual with ADC in terms of possible communication difficulties, and to define the role of the speech-language therapist in this regard. A single case study, non-experimental, descriptive research design was used. The research participant’s narrative was elicited by means of natural conversation and recorded on audio tape. The narrative was transcribed and analysed, using the following three methods: 1.) Plot analysis, 2.) Structural story analysis according to Labov’s (1982) structural approach, and 3.) Holistic content analysis. According to the plot analysis this was a regressive narrative. During the discussion of the meta-narratives, different aspects of the research participant's personal illness experience were identified as regards the influence thereof on her ability to maintain her quality of life through participating in everyday living activities. The ICF components were used as framework to present the results obtained in a meaningful manner. It also became apparent that the illness experience cannot be isolated to specific human functions, such as communication. The experience of her communication problems is part of her complete illness experience, which takes place in the context of her everyday living activities and participation therein. The identification and analysis of themes also indicated that the narrative is an effective method to gain insight into the individual’s context and experience thereof. A holistic view could be obtained of the individual’s functional skills, context and emotional experience and needs, without subjecting her to formal tests and evaluation instruments which might leave her feeling incompetent and inferior. The results obtained imply that the individual with ADC’s illness experience is central to the extent to which he or she participates in everyday life activities as well as to the quality of life experienced. The value of narratives in the therapeutic treatment process also became apparent. Narratives can successfully be applied to gain better insight into the life and needs of the individual living with ADC. / Dissertation (M (Communication Pathology))--University of Pretoria, 2006. / Speech-Language Pathology and Audiology / unrestricted

This research is aimed at the needs of counsellors working with children infected and affected by HIV/AIDS. A lack of sufficient guidelines for this field has been identified in the relevant literature. This shortage has been confirmed by experienced counsellors working with children. To reach the required goal a number of objectives were set. This included setting up a theoretical framework by way of a literature study as well as consultation with experts in the field; studying the developmental needs of children in the mid childhood phase and how these needs are influenced by HIV/AIDS; the need for guidance of children affected by AIDS as well as the role that counsellors can play in this regard. An empirical study was undertaken during which focus group interviews were held with a group of lay counsellors as well as a group of trained counsellors. Ten participants took part in the focus groups. Applied research was undertaken as the researcher aimed at establishing the true needs of counsellors working in the field. The empirical data showed the following: Ø Counsellors feel that they have a specific role to play during the therapy with AIDS-affected children. Ø Counsellors have definite views on the needs of children affected by AIDS. Ø Counsellors have listed specific skills and training needed by therapists working with these children. Ø Counsellors have listed definite shortcomings and needs that they experience in their work with AIDS-affected children. The basic need for the establishing of a protocol to be used in guidance of children infected and affected by AIDS was one of the key findings of the study. / Dissertation (MSD (Play Therapy))--University of Pretoria, 2005. / Social Work and Criminology / Unrestricted

Thesis (MSc (Psychology))--Stellenbosch University, 2008. / As part of the South African government’s strategy to support those with HIV/AIDS and their relatives, HIV/AIDS service points have been established at Public Health Facilities. An increasing number of HIV-positive children and their caretakers receive treatment here. Indirectly the paediatric patients’ uninfected caretakers and the adult patients’ children also come into contact with the Public Health System during visits. The HIV-positive and uninfected children and caretakers form a heterogeneous HIV/AIDS-affected population, which may experience particular fears due to their particular circumstances. Circumstance-particular coping strategies may be necessary. Children do, however, also experience normative childhood fears and their coping strategies display developmental characteristics. Direct and indirect learning experiences furthermore may contribute to children’s experience of fear. The participants were 40 HIV/AIDS-affected children (M = 9.4 years; HIV-positive = 30.0%) and their caretakers (N = 34; M = 36.7 years; HIV-positive = 76.5%) who had been in contact with the Public Health System of the Western Cape Province, South Africa. There were five sub-objectives. Regarding the children the objectives were to consider, against the background of normative literature, whether the target group was a special population regarding their (1) fears and (2) coping strategies. Furthermore the objective was (3) to get to know the children’s world through their learning experiences. Concerning the caretakers the objectives were to explore their personal (4) fears and (5) coping strategies. In addition the caretakers’ perceptions about their children’s fears and coping strategies were gathered. The study was explorative and a mixed methodological research model was used. Data were gathered through individual interviews. The children also completed the Goodenough-Harris Drawing Test (GHD) and the caregivers a demographic questionnaire. Data were analysed by using a combination of qualitative and quantitative strategies. The children reported normative childhood fears, mainly of wild animals. A substantial minority of the children reported fears connected to crime, an unsafe transport system, death, illness, and HIV/AIDS and special circumstances were therefore identified. The children’s coping strategies were circumstance-specific and problem-focused avoidance reported most. Living in a modern society these children’s fears have also been influenced by for instance television. The fears and coping strategies reported by the children and their care-takers’ perceptions thereof, concurred. The caretakers’ personal fears mainly were connected to psycho-social needs and social roles, which stand central during adulthood. Specifically fears about the children’s welfare were reported most. The caretakers reported crime and animalrelated fears similar to their children. A search for social support as well as preventative action were the coping strategies that were reported most. A noteworthy preventative-action strategy seemed to be healthy eating habits, given the controversy about natural products being used as HIV/AIDS treatment within the South African context. The findings were integrated within a systems-theoretical framework. The fears and coping strategies of the HIV/AIDSaffected children and their caretakers were interpreted to be the result of an interaction between their personal characteristics and their social environment.

The study is aimed at looking at the emotional needs the HIV/Aids affected coloured child in middle childhood. An in depth literature study was done and shortcomings have been identified with regard to the HIV/Aids affected child, in specific the experience of the child within the period before the loss of a parent because of HIV/Aids. A number of objectives were set in order to reach the goal of this study. By the consultation of literature and experts working in the field of HIV/Aids affected children in middle childhood, a theoretical framework was set up which included the following aspects: HIV/Aids in Sub Sahara Africa, the impact of HIV/Aids on the South African society, the HIV/Aids infected and –affected child, the impact of HIV/Aids on the family, the psycho social-, emotional- and social development of the child in middle childhood and cultural diversity in South Africa (with specific reference to the coloured culture and counselling for these children). During an empirical study, semi-structured interview techniques were applied as a method for data collection in order to assess the emotional needs of the HIV/Aids affected coloured child in middle childhood. Interviews focused on the HIV/Aids child and the following aspects were handled: the child’s wishes at that specific time in life (excluding the parent’s HIV/Aids status), the child’s experience of other’s interest in his own well being, the duration of the child’s knowledge of the parent’s HIV/Aids status, concerning changes (at school or at home) in the life of the child due to the parent’s HIV/Aids status, the child’s future custody and his feelings and ideas about it, individuals whom this child can talk to about his feelings of distress/anger/hurt, the child’s feelings about the knowledge concerning the parent’s HIV/Aids status and the child’s experience of newly acquired responsibilities at home (or towards his siblings) since the parents were HIV/Aids infected. Applied research was undertaken to aid the researcher in enhancing the awareness of professionals in practice with regard to the emotional needs of the affected coloured children in middle childhood. The professionals can then be empowered to understand and handle the problems which can be caused by the unfulfilled emotional needs of the HIV/Aids affected children. A qualitative research approach was used in gathering data, in order to get a full understanding of the emotional needs of the HIV/Aids affected child. A phenomenological strategy within an exploratory study was used aiming to understand and interpret the research question. The research question for this study is: “What are the emotional needs of the HIV/Aids affected coloured child in middle childhood?” Empirical data was obtained by means of an interview schedule and verified the following: -- The HIV/Aids affected coloured child in middle childhood experiences the need for emotional safety, which is threatened by the knowledge of the possibility of the death of a parent, and insecurity considering their future custody. The child is experiencing a variety of emotions of which bereavement is the most common one. The child’s emotional safety is also threatened by other factors associated with the parent’s HIV/Aids status. -- The HIV/Aids affected coloured child in middle childhood expresses the need to debriefing. It is common that these children do not have someone to share emotions with. Proof of above mentioned assumption can be ascribed to three factors namely: the people involved are not aware of the need for debriefing, the perception that it is better for the child not to express their emotions regarding the parent’s HIV/Aids infection and last, the lack of skills on ‘know how’ in approaching and handling this specific situation. -- The HIV/Aids affected coloured child in middle childhood experiences intense emotions concerning the parent’s HIV/Aids status whereas bereavement, concern and sympathy are identified. A few of these children are partly in denial about their parents’ HIV/Aids status and claim that the parents will die because of Tuberculoses. A number of these children totally deny the fact that their parents are sick. To assist the child in handling the related emotions and the traumatic situation, it will be beneficial to get therapeutic support. -- The HIV/Aids affected coloured child in middle childhood experiences drastic change when the parent’s HIV/Aids status is disclosed, or the moment the child starts to realise that something is wrong. The HIV/Aids parent is concerned about the impact of disclosure on the child and therefore delays this process. When the parent’s HIV/Aids status is disclosed, the child experiences a crisis and does not have the inner strength or required skills to handle his emotions and the situation which he is confronted with. -- The HIV/Aids affected coloured child in middle childhood experiences a need for acceptance by peer group members and therefore fear that they will discover their parent’s status. It became clear that in cases where the peers have found out about the HIV/Aids infected parent, their reactions were negative. Because of this, the HIV/Aids affected child experiences anger and grief. -- The HIV/Aids affected coloured child in middle childhood experiences a lack of concentration at school, which has a direct negative impact on his school performance. School attendance is also influenced negatively because of the other children’s negative attitude towards them. Seeing that school, as a formal institution, will influence the child’s social-, emotional- and psycho social development, it is of importance that the HIV/Aids affected child is supported in his scholastic functioning. This study exposed the emotional needs of the HIV/Aids affected coloured child in middle childhood which holds possibility for future research. The information collected can be utilized for further studying purposes and the intervention of children in similar situations. / Dissertation (MSD (Play Therapy))--University of Pretoria, 2006. / Social Work / unrestricted

Thesis (MPhil (Sociology and Social Anthropology))--University of Stellenbosch, 2009. / This thesis is about children who are vulnerable in the context of HIV/AIDS. The epidemic leaves children vulnerable in a number of ways. The education sector is confronted with vulnerable children and this has caused the roles and responsibilities of teachers to be extended. The research is aimed at determining whether teachers see a role for themselves in this context that extends beyond formal education and also to find out how teachers view this role. The research was conducted at three schools in the Llingelethu community in Malmesbury: a pre-primary school (the Siphumeze Educare Centre), a primary school (Naphakade Primary School) and a high school (Naphakade Secondary School). The research determined that teachers do feel that they have a role in this context, but there were also those who felt that other role players must rather fulfil this role. One of the most important findings of the research was that teachers often view their role in the context of HIV/AIDS in a limited way. In this regard, teachers often think only in terms of children who are infected by die virus, while not taking into account children who are affected in other ways. Teachers, as well as schools, also often still focus on their role in HIV/AIDS prevention. A further aim of the research was to determine which challenges prevent teachers from playing an extended role in the lives of vulnerable children. The participants in the research identified various challenges, including those that are a result of keeping HIV status secret, because of stigma and a lack of trust. A further challenge that was identified is a lack of background information about learners, sometimes as a result of the fact that teachers do not come from the community. Factors that make it difficult for teachers to conduct follow up work were also identified, as well as emotional exhaustion and other facors that prevent teachers from playing an extended role. A lack of support was also identified by participants as a challenge and different dimensions of support were identified.

Hoofstuk 1 benadruk die sentrale en skerpsinnig-wyse sleutelposisie van eskatologiese hoop en getuienis daarvan in die lewens van gelowige terminale MIV/VIGS Iyers. 'n Eksegetiese studie van Johannes 9:1-8, Lukas 5:12-15, Job 1:6-22; 2:3-13, Genesis 2:1617, Romeine 5:2-5; 6:5-11; 8:18-25, 1 Petrus 1:3-9 en Matteus 28:19-20 is die studiekern van Hoofstuk 2. Siekte (blindheid, melaatsheid), Iyding en pyn (Job), dood van die mensdom (Adam en Eva) en die retrovitale dood van Jesus Christus, hoop en getuienis is nagevors en ontleed. Vergelykings met huidige tendense waar MIV/VIGS 'n gestigmatiseerde terminale siekte is, word getref. Die basis van hoop op die ewige lewe in die volle teenwoordigheid van God Almagtig, is die beloftes en oorweldigende liefde van die lewende God. Getuienis van hierdie standhoudende en lewende hoop is die Groot Opdrag aan die dissipels van Christus in Matteus 28:19-20, en daarom aan alle gelowiges tot die wederkoms (advent) van Christus. Hoofstuk 3 stel die bydrae vas van die metateorieë van die mediese -, kommunikasiewetenskappe en Psigologie as komplementerende ervaringvelde. Die mediese en sosiale omstandighede van die gelowige terminale MIV/VIGS Iyers toon 'n uiters negatiewe situasie, wat onder meer bestuurbaar gemaak word deur die sogenaamde "signature strengths" van die Positiewe Psigologie. Op 'n veel hoer vlak is spirituele gesondheid en heling, as die vrug van die Hel/lge Gees, van kardinale belang vir die ewige lewe. Hierdie metateorieë bevestig die waarhede rakende die Groot Geneesheer soos in Hoofstuk 2 aangedui, en voorsien verder verhelderende perspektiewe op 'n nuwe prakties-teologiese teorie. Empiriese navorsing aan die hand van 'n kwalitatiewe studie by die gesondheidsentrum van 'n voorstedelike motorvervaardigingaanleg, word in Hoofstuk 4 onderneem. In twee groeponderhoude met multi-veranderlikes per deelnemer (gelowige terminale MIV/VIGS Iyers en 'n kontrolegroep van mediese personeel/gesondheidwerkers), is vasgestel dat die MIV/VIGS Iyers versterkende geestelike krag van hul eskatologiese hoop vir die ewige lewe saam met God, ervaar. Pastorale behoeftes sluit gebed, vertroosting en koinonia/"fellowship" in. Hoofstuk 5 stel praktiese riglyne voor tot kerugmatiese -, liturgiese -, koinoniale -en diakoniale getuienis oor hoop. Versoening met God deur die "retrovitale" liefde/dade van Jesus Christus se dood as die spil-as wat radikaal-Skriftuurlike denke/lewe inisieer (in teenstelling met die "retrovirale" vermoë van die MI-virus waar die "kwaad" vermenigvuldig), word in die riglyne aangemoedig. Getuienis oor hoop aan ander is die "geskenk van die Lewe”. Die slotsom waartoe gekom word, is dat die gelowige terminale MIV/VIGS Iyer tot in die vierde fase van die siekte, oor haar/sy hoop kan getuig. Praktiese riglyne hiertoe moedig die gelowige met enige terminale siekte of in elk geval, aan om met 'n lewe van aanbidding oor hierdie hoop te getuig en s6 die lewende God te eer. / Chapter 1 emphasizes the central and perspicacious position of eschatological hope and witnessing thereof, in the lives of the believing terminal HIV/AIDS sufferers. An exegetical study of John 9:1-8, Luke 5:12-15 Job 1:6-22; 2:3-13, Genesis 2:16-17, Romans 5:2-5; 6:511; 8:18-25, 1 Peter 1 :3-9 and Matthew 28: 19-20 is conducted in Chapter 2. Illnesses (blindness, leprosy), suffering and pain (Job), death of mankind (Adam and Eve) and the retrovital death of Jesus Christ, hope and witnessing are researched and analysed. Comparisons with life today where HIV/AIDS is a stigmatised terminal illness, are weighed. Hope for eternal life in the full presence and reign of God Almighty, is based on the promises and overwhelming love of the living God. Witnessing of this vivacious and living hope is imperative to the disciples of Christ in Matthew 28: 19-20, and therefore to all believers until the advent of Christ. Chapter 3 establishes the contribution of meta theories of complementary and entwined sciences, such as health and medicine, communications and the positive psychology. The medical and social circumstances of the believing terminal HIV/AIDS sufferers revealed an extremely grave situation, which is manageable with inter alia positive "signature strengths". On a much higher plain, spiritual health and healing as the fruit of the Spirit, is of cardinal importance for eternal life. These theories only confirm the truths about the Great Healer as stated in Chapter 2 and provide enlightening perspectives for a new practical theological theory. Empirical research via a qualitative study at the health centre of an urban vehicle manufacturing plant, is conducted in Chapter 4. Two group interviews with multi-variables per participant (believing terminal HIV/AIDS sufferers and a control group of health workers), have established that the HIV/AIDS sufferers are spiritually enormously strengthened by their eschatological hope for eternal life with God, without this earthly suffering. Pastoral needs include prayer, comfort and koinonia/fellowship. Chapter 5 suggests practical guidelines in terms of witnessing hope by means of cherugmatical, liturgical, koinonial and diaconial communication. The image of the 'retrovital' Lord Jesus Christ as the pivotal change that paths the way to radical Biblical thinking/living (in comparison with the "retroviral" ability of the. HI-virus which multiplies the "evil"), is encouraged. The final conclusion is that a believing terminal HIV/AIDS sufferer is able to witness hope for eternal life until the fourth phase of the terminal illness. Practical guidelines hereto may encourage the believer of any terminal illness or in any case, to witness hope with a life of worship and thus honour the living God. / Thesis (M.A. (Practical Theology))--North-West University, Potchefstroom Campus, 2010.

Hoofstuk 1 benadruk die sentrale en skerpsinnig-wyse sleutelposisie van eskatologiese hoop en getuienis daarvan in die lewens van gelowige terminale MIV/VIGS Iyers. 'n Eksegetiese studie van Johannes 9:1-8, Lukas 5:12-15, Job 1:6-22; 2:3-13, Genesis 2:1617, Romeine 5:2-5; 6:5-11; 8:18-25, 1 Petrus 1:3-9 en Matteus 28:19-20 is die studiekern van Hoofstuk 2. Siekte (blindheid, melaatsheid), Iyding en pyn (Job), dood van die mensdom (Adam en Eva) en die retrovitale dood van Jesus Christus, hoop en getuienis is nagevors en ontleed. Vergelykings met huidige tendense waar MIV/VIGS 'n gestigmatiseerde terminale siekte is, word getref. Die basis van hoop op die ewige lewe in die volle teenwoordigheid van God Almagtig, is die beloftes en oorweldigende liefde van die lewende God. Getuienis van hierdie standhoudende en lewende hoop is die Groot Opdrag aan die dissipels van Christus in Matteus 28:19-20, en daarom aan alle gelowiges tot die wederkoms (advent) van Christus. Hoofstuk 3 stel die bydrae vas van die metateorieë van die mediese -, kommunikasiewetenskappe en Psigologie as komplementerende ervaringvelde. Die mediese en sosiale omstandighede van die gelowige terminale MIV/VIGS Iyers toon 'n uiters negatiewe situasie, wat onder meer bestuurbaar gemaak word deur die sogenaamde "signature strengths" van die Positiewe Psigologie. Op 'n veel hoer vlak is spirituele gesondheid en heling, as die vrug van die Hel/lge Gees, van kardinale belang vir die ewige lewe. Hierdie metateorieë bevestig die waarhede rakende die Groot Geneesheer soos in Hoofstuk 2 aangedui, en voorsien verder verhelderende perspektiewe op 'n nuwe prakties-teologiese teorie. Empiriese navorsing aan die hand van 'n kwalitatiewe studie by die gesondheidsentrum van 'n voorstedelike motorvervaardigingaanleg, word in Hoofstuk 4 onderneem. In twee groeponderhoude met multi-veranderlikes per deelnemer (gelowige terminale MIV/VIGS Iyers en 'n kontrolegroep van mediese personeel/gesondheidwerkers), is vasgestel dat die MIV/VIGS Iyers versterkende geestelike krag van hul eskatologiese hoop vir die ewige lewe saam met God, ervaar. Pastorale behoeftes sluit gebed, vertroosting en koinonia/"fellowship" in. Hoofstuk 5 stel praktiese riglyne voor tot kerugmatiese -, liturgiese -, koinoniale -en diakoniale getuienis oor hoop. Versoening met God deur die "retrovitale" liefde/dade van Jesus Christus se dood as die spil-as wat radikaal-Skriftuurlike denke/lewe inisieer (in teenstelling met die "retrovirale" vermoë van die MI-virus waar die "kwaad" vermenigvuldig), word in die riglyne aangemoedig. Getuienis oor hoop aan ander is die "geskenk van die Lewe”. Die slotsom waartoe gekom word, is dat die gelowige terminale MIV/VIGS Iyer tot in die vierde fase van die siekte, oor haar/sy hoop kan getuig. Praktiese riglyne hiertoe moedig die gelowige met enige terminale siekte of in elk geval, aan om met 'n lewe van aanbidding oor hierdie hoop te getuig en s6 die lewende God te eer. / Chapter 1 emphasizes the central and perspicacious position of eschatological hope and witnessing thereof, in the lives of the believing terminal HIV/AIDS sufferers. An exegetical study of John 9:1-8, Luke 5:12-15 Job 1:6-22; 2:3-13, Genesis 2:16-17, Romans 5:2-5; 6:511; 8:18-25, 1 Peter 1 :3-9 and Matthew 28: 19-20 is conducted in Chapter 2. Illnesses (blindness, leprosy), suffering and pain (Job), death of mankind (Adam and Eve) and the retrovital death of Jesus Christ, hope and witnessing are researched and analysed. Comparisons with life today where HIV/AIDS is a stigmatised terminal illness, are weighed. Hope for eternal life in the full presence and reign of God Almighty, is based on the promises and overwhelming love of the living God. Witnessing of this vivacious and living hope is imperative to the disciples of Christ in Matthew 28: 19-20, and therefore to all believers until the advent of Christ. Chapter 3 establishes the contribution of meta theories of complementary and entwined sciences, such as health and medicine, communications and the positive psychology. The medical and social circumstances of the believing terminal HIV/AIDS sufferers revealed an extremely grave situation, which is manageable with inter alia positive "signature strengths". On a much higher plain, spiritual health and healing as the fruit of the Spirit, is of cardinal importance for eternal life. These theories only confirm the truths about the Great Healer as stated in Chapter 2 and provide enlightening perspectives for a new practical theological theory. Empirical research via a qualitative study at the health centre of an urban vehicle manufacturing plant, is conducted in Chapter 4. Two group interviews with multi-variables per participant (believing terminal HIV/AIDS sufferers and a control group of health workers), have established that the HIV/AIDS sufferers are spiritually enormously strengthened by their eschatological hope for eternal life with God, without this earthly suffering. Pastoral needs include prayer, comfort and koinonia/fellowship. Chapter 5 suggests practical guidelines in terms of witnessing hope by means of cherugmatical, liturgical, koinonial and diaconial communication. The image of the 'retrovital' Lord Jesus Christ as the pivotal change that paths the way to radical Biblical thinking/living (in comparison with the "retroviral" ability of the. HI-virus which multiplies the "evil"), is encouraged. The final conclusion is that a believing terminal HIV/AIDS sufferer is able to witness hope for eternal life until the fourth phase of the terminal illness. Practical guidelines hereto may encourage the believer of any terminal illness or in any case, to witness hope with a life of worship and thus honour the living God. / Thesis (M.A. (Practical Theology))--North-West University, Potchefstroom Campus, 2010.

Antiretroviral drugs are successful in controlling HIV/AIDS and reducing disease progression. Antiretroviral regimens are stopped in up to 25% of all patients during their initial treatment therapy as a result of adverse drug effects, failing treatment and nonadherence within the initial eight months of treatment (Sharma et al., 2007: 235). A pharmacovigilance surveillance system makes it possible for physicians, pharmacists and other healthcare providers to report suspected ADRs. The purpose of this system is to operate as a guide in identification of new ADRs and predisposing risk factors to known ADRs. The objective of this study was to assess the prevalence and documentation of adverse drug reactions (ADR) in the private and public antiretroviral clinics in Maseru district, with special reference to zidovudine (AZT) and tenofovir (TDF) - based regimens. The empirical investigation was divided into two phases. The first phase was a cross-sectional quantitative retrospective drug utilisation review study which focused on the occurrence of adverse drug reactions in patients taking zidovudine (AZT) and tenofovir (TDF). The second phase, a survey in a form of questionnaires for the health professionals. Drug utilisation review: The sample size of patients was 300. Of the 44 patients who experience ADRs, 72.73% (n = 32) were female and 27.27% (n = 12) were male. A greater number of patients who experienced ADRs were females with 43.18% (n = 19) presenting with skin rash, 27.27% (n = 12) with nausea/vomiting, and 2.27% (n = 1) with diarrhoea. In male patients, 2.27% (n = 1) had peripheral neuropathy, 18.18% (n = 8) skin rash, 2.27% (n = 1) Fanconi syndrome, 2.27% (n = 1) nausea/vomiting, and 2.27% (n = 1) diarrhoea. Patients whose ART regimen changed due to ADRs were five. 60% (n = 3) of the patients were females and 40% (n = 2) were males. There was an estimated increase of 0.0025 cell/mm³, 0.0026 cell/mm³, 0.0024 cell/mm³, 0.0025 cell/mm³, and of 0.0019 cell/mm³ in CD4 cell count per day according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. An estimated increase of 0.00021 g/dL, 0.00022 g/dL, 0.00018 g/dL, 0.00022 g/dL, and of 0.00020 g/dL in Hb profile per day occurred according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. There was an estimated increase of 0.000062%, 0.000046%, 0.000068%, 0.000062%, and of 0.00017% in neutrophil count according to sex, age group, weight group, initial ART regimen, and ADRs per day, respectively. There was an estimated increase of 0.000044 IU/L, 0.000043 IU/L, 0.000046 IU/L, and of 0.000028 IU/L in ALT according to sex, age group, weight group, and initial ART regimen per day, respectively. An estimated decrease of 0.000013 IU/L in ALT according to ADRs per day also occurred. There was an estimated decrease of 0.00038 μmol/L, 0.00039 μmol/L, 0.00040 μmol/L, 0.00040 μmol/L, and of 0.00028 μmol/L in serum creatinine per day according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. There was an estimated decline of 0.00023 mmol/L, 0.00022 mmol/L, 0.00023 mmol/L, 0.00024 mmol/L, and of 0.00015 mmol/L per day in urea according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. Health professional’s questionnaire: 49 health professionals responded to the questionnaire. 100% (n= 49) of the participants showed that they did not use the yellow card scheme to report ADRs. 34.65% (n = 17) use the individual case safety reports. 57.14% (n = 28) used the structured databases to report ADRs. 85.71% (n = 42) documented in the patient bukana, and 6.12% (n = 3) used the HIV/AIDS ART card to document ADRs occurrence. 91.84% (n = 45) of the health professionals never filled the ADR reporting form in their working environment. In conclusion, adverse drug reactions occurring in a hospital or healthcare facility should be recorded and reported by the medical practitioners, nurses, pharmacists, and the pharmacy technicians. Therefore, it is important to assess the continuous evaluation of the benefits and harm of medicines which will help in achieving the ultimate goal of making safer and more effective treatment available for patients. As well as to help the health professionals to participate in the very important process of continuous surveillance of safety and efficacy of pharmaceutical products used in clinical practice. / MPham (Pharmacy Practice), North-West University, Potchefstroom Campus, 2014

Antiretroviral drugs are successful in controlling HIV/AIDS and reducing disease progression. Antiretroviral regimens are stopped in up to 25% of all patients during their initial treatment therapy as a result of adverse drug effects, failing treatment and nonadherence within the initial eight months of treatment (Sharma et al., 2007: 235). A pharmacovigilance surveillance system makes it possible for physicians, pharmacists and other healthcare providers to report suspected ADRs. The purpose of this system is to operate as a guide in identification of new ADRs and predisposing risk factors to known ADRs. The objective of this study was to assess the prevalence and documentation of adverse drug reactions (ADR) in the private and public antiretroviral clinics in Maseru district, with special reference to zidovudine (AZT) and tenofovir (TDF) - based regimens. The empirical investigation was divided into two phases. The first phase was a cross-sectional quantitative retrospective drug utilisation review study which focused on the occurrence of adverse drug reactions in patients taking zidovudine (AZT) and tenofovir (TDF). The second phase, a survey in a form of questionnaires for the health professionals. Drug utilisation review: The sample size of patients was 300. Of the 44 patients who experience ADRs, 72.73% (n = 32) were female and 27.27% (n = 12) were male. A greater number of patients who experienced ADRs were females with 43.18% (n = 19) presenting with skin rash, 27.27% (n = 12) with nausea/vomiting, and 2.27% (n = 1) with diarrhoea. In male patients, 2.27% (n = 1) had peripheral neuropathy, 18.18% (n = 8) skin rash, 2.27% (n = 1) Fanconi syndrome, 2.27% (n = 1) nausea/vomiting, and 2.27% (n = 1) diarrhoea. Patients whose ART regimen changed due to ADRs were five. 60% (n = 3) of the patients were females and 40% (n = 2) were males. There was an estimated increase of 0.0025 cell/mm³, 0.0026 cell/mm³, 0.0024 cell/mm³, 0.0025 cell/mm³, and of 0.0019 cell/mm³ in CD4 cell count per day according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. An estimated increase of 0.00021 g/dL, 0.00022 g/dL, 0.00018 g/dL, 0.00022 g/dL, and of 0.00020 g/dL in Hb profile per day occurred according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. There was an estimated increase of 0.000062%, 0.000046%, 0.000068%, 0.000062%, and of 0.00017% in neutrophil count according to sex, age group, weight group, initial ART regimen, and ADRs per day, respectively. There was an estimated increase of 0.000044 IU/L, 0.000043 IU/L, 0.000046 IU/L, and of 0.000028 IU/L in ALT according to sex, age group, weight group, and initial ART regimen per day, respectively. An estimated decrease of 0.000013 IU/L in ALT according to ADRs per day also occurred. There was an estimated decrease of 0.00038 μmol/L, 0.00039 μmol/L, 0.00040 μmol/L, 0.00040 μmol/L, and of 0.00028 μmol/L in serum creatinine per day according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. There was an estimated decline of 0.00023 mmol/L, 0.00022 mmol/L, 0.00023 mmol/L, 0.00024 mmol/L, and of 0.00015 mmol/L per day in urea according to sex, age group, weight group, initial ART regimen, and ADRs, respectively. Health professional’s questionnaire: 49 health professionals responded to the questionnaire. 100% (n= 49) of the participants showed that they did not use the yellow card scheme to report ADRs. 34.65% (n = 17) use the individual case safety reports. 57.14% (n = 28) used the structured databases to report ADRs. 85.71% (n = 42) documented in the patient bukana, and 6.12% (n = 3) used the HIV/AIDS ART card to document ADRs occurrence. 91.84% (n = 45) of the health professionals never filled the ADR reporting form in their working environment. In conclusion, adverse drug reactions occurring in a hospital or healthcare facility should be recorded and reported by the medical practitioners, nurses, pharmacists, and the pharmacy technicians. Therefore, it is important to assess the continuous evaluation of the benefits and harm of medicines which will help in achieving the ultimate goal of making safer and more effective treatment available for patients. As well as to help the health professionals to participate in the very important process of continuous surveillance of safety and efficacy of pharmaceutical products used in clinical practice. / MPham (Pharmacy Practice), North-West University, Potchefstroom Campus, 2014

During the past decade, South Africa has become the country with the highest number of HIV/AIDS infections in the world. In the wake of the widely spread HIV/AIDS epidemic in South Africa, hundreds of thousands of children are left parentless. Since limited research exists on the psycho-educational needs of children orphaned by AIDS in South Africa, the focus of this study was on their psycho-educational development. A literature study was conducted to investigate the HIV/AIDS epidemic in South Africa and its consequences for the psycho-educational development of AIDS orphans. A qualitative investigation was undertaken and interviews were conducted with caregivers of AIDS orphans at two care centres in rural KwaZulu-Natal. The aim of the investigation was to identify the psycho-educational needs of AIDS orphans as perceived by their caregivers. Moreover, the investigation also aimed at identifying factors that impede the psycho-educational development of AIDS orphans, and to determine the extent to which these day care centres meet the psycho-educational needs of these orphans. The following psycho-educational needs of AIDS orphans emerged from the investigation: - the need to socialise and communicate - the need to cope with parental death - the need for acceptance - the need for security and care - the need for love and belonging - the need to deal with negative emotions Physical and material needs were added to the above needs, since these were frequently mentioned during the course of the interviews. Factors that seriously impeded the psycho-educational development of AIDS orphans were abuse and neglect. The investigation also revealed that the care centres were to a large extent able to meet a broad spectrum of these orphans’ psycho-educational needs, especially at the care centre where the AIDS orphans were able to sleep over and received the full-time attention caregivers. Since the extended family system can no longer fully carry the burden of hundreds of thousands of AIDS orphans in South Africa, care centres situated in the affected communities can offer a viable alternative to traditional models of care. The study emphasised the need for further research on the needs of AIDS orphans as well as increased support of AIDS orphans on local, provincial and national levels. / MEd (Learner support), North-West University, Potchefstroom Campus, 2012