LCModel, which is performed on Linux, has been widely used for quantitative analysis of MRS. Its interface, LCMgui, converts MRS data of various formats to RAW file for LCModel analysis automatically. In this work, we had a web-based MRS analysis tool for GE MRS, GE MRS with Phase-Array and GE 2D-MRSI and improve the capability of web-based MRS analysis tool for GE 3D-MRSI, Siemens MRS/MRSI, and Philips MRS/MRSI. Meanwhile, T2 correction has been involved in the absolute quantification with LCModel. With the same echo-time, the different T2 value of each metabolite results in different degree of signal decay. In order to correct and make absolute concentrations more accurate, we exploit a factor to correct effect of different T2. Two groups of MRS data (TE = 35 and 272 ms) have been studied for comparison.

Thesis (M.Sc.) - Carleton University, 2005. / Includes bibliographical references (p. 106-119). Also available in electronic format on the Internet.