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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

The development of web-based MRS analysis tool with T2 Correction

Yang, Ming-che 28 January 2010 (has links)
LCModel, which is performed on Linux, has been widely used for quantitative analysis of MRS. Its interface, LCMgui, converts MRS data of various formats to RAW file for LCModel analysis automatically. In this work, we had a web-based MRS analysis tool for GE MRS, GE MRS with Phase-Array and GE 2D-MRSI and improve the capability of web-based MRS analysis tool for GE 3D-MRSI, Siemens MRS/MRSI, and Philips MRS/MRSI. Meanwhile, T2 correction has been involved in the absolute quantification with LCModel. With the same echo-time, the different T2 value of each metabolite results in different degree of signal decay. In order to correct and make absolute concentrations more accurate, we exploit a factor to correct effect of different T2. Two groups of MRS data (TE = 35 and 272 ms) have been studied for comparison.

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