Rostock, R.- u. wirtschaftswiss. Diss. v. 21. Jan. 1935.

Thesis (doctoral)--Universitẗ Jena.

Class of 2007 Abstract / Objectives: The purpose/objective of this study is to determine the effects of heat exposure, on the levels of active ingredient in three selected medications with narrow therapeutic indices: levothyroxine, epinephrine, and timolol. Methods: In order to complete the study, a variety of methods were carried out to simulate the desired and appropriate environmental conditions. The drug selection was based on the medications pharmacokinetic properties. Levothyroxine was considered ideal to include in the study due to the medication's short shelf life and narrow therapeutic window. Epinephrine was selected since it is a life-saving medication, which has been reported to degrade to a significant extent under extreme heat. Timolol was chosen since its liquid formulation can be unstable when exposed to extreme heat. Epi- Pen ®, levothyroxine 150 mcg, and timolol 0.5% were mailed from Phoenix on 7/12/06, via FedEx in order to simulate the mail order prescription delivery process. Alternatively, other samples of the medications were also placed at room temperature and a variety of heat and humidity conditions. The temperature and relative humidity profiles for the mail order drugs were monitored by a temperature and RH device. Three different assessments were made for each drug. Within each assessment, three analyses were conducted on that same sample. For the timolol drops, each 5ml (??)bottle was assayed three times in addition to baseline measurements. Likewise, the levothyroxine tablets and epinephrine injections each were analyzed three times from the same sample, from three different lots. In addition, we also examined the degredation of these three drugs when subjected to constant temperature exposure of 37, 45, 45 with RH, and 55 degrees Celsius in a lab oven. Samples were collected after 1-. 4-, and 7-days of heat exposure in both the mail box and the oven; 7/14/06, 7/17/06, and 7/20/06, respectively. Each medication was analyzed by its respective high-performance liquid chromatography (HPLC) method. The amount of drug taken for each sample was 0.5mL of epinephrine, 10 tablets of levothyroxine, and 0.5mL of timolol were used in the preparation for HPLC analysis. Results: The temperature and RH profile were recorded and graphed. The temperature measured in the mail box ranged from ~75 degreees Fahrenheit to ~140 degrees Fahrenheit. Based on the extrapolation to the baseline, the amount of drug measured on days 1, 4, and 7 were the following: 1) Levothyroxine: 123.66 mcg, 118.61mcg, and 119.3 mcg, respectively; 2) EpiPen: 1121.48 mcg/ml, 1215.52 mcg/ml, and 1167.22 mcg/ml, respectively; 3) timolol: 6766.30 mcg/ml, 6659.52 mcg/ml, and 6508.48 mcg/ml, respectively. Conclusions: The medications studied were exposed to temperatures above the manufacturer’s recommended storage conditions for the majority of the time. Despite being out of opitmal conditions, the results indicated that all three drugs did not have significant degradation.

This report includes the process of developing and writing the feature length screenplay Derailment, a thriller about Vietnamese mail-order brides murdered in Taiwan. In addition to the evolution of the screenplay, I have offered the summation of my learning experience in the UT screenwriting M.F.A. program / text

Class of 2005 Abstract / Objective: To determine whether prescription medication vials are exposed to excessive temperatures during delivery by mail or truck by recording temperatures continuously throughout the delivery process. Methods: During one part of the study, temperatures were recorded, starting when the package, housing the prescription vial and digital thermometer, was placed in the mailbox in Phoenix and continued every 15 minutes until the package was retrieved from the researcher’s mailbox in Tucson. During the second component of the study, temperatures were recorded starting when the package was dropped off at the shipping facility and continued every 15 minutes throughout ground delivery by truck until the package was delivered to the researcher’s home. Ten trials were done for each arm of the study on five different days, with two packages for each arm being sent each time. Results: There were 1,300 temperature readings for the mail arm of the study. Five hundred twenty-two temperature readings were in excess of the desired range of 59-86ο F; for a percentage of 40.1%. For the truck arm of the study, there were 1,272 temperature readings. Three hundred sixty-nine temperature readings were in excess of the desired range; a percentage of 29.0%. Temperature readings ranged from 69.8-111.2ο F for the mailed packages and 70.7-120.5ο F for the packages sent by truck. Conclusions: Prescription medication vials are subjected to excessive temperatures during delivery by mail and truck.

No description available.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1973. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliography.

Online international introduction sites that offer romance tours to American men in search of a foreign bride are an important and rapidly growing component of the internet dating industry; the number of these agencies in the U.S. tripled from two hundred to six hundred in the past 10 years. Previous scholars have examined the so-called ‘mail order bride’ industry in order to demonstrate that the women involved are agents and not victims. Many scholars have also highlighted the importance of race in shaping American men’s desires in one particular region or country. My dissertation provides an important addition to the literature surrounding romance tourism by including participants from all three major regions associated with romance tourism: Eastern Europe, South America, and Southeast Asia. I collected the data for the dissertation by becoming a participant observer of a romance tour in Ukraine, Colombia, and the Philippines. I argue that romance tourism is an important example of the global intimate, and the ways in which globalized processes are created and sustained through everyday intimate emotions and interactions. By examining the ways in which the emotions of desire, disgust, and anxiety influence individual romance tour participant’s constructions of racialized hierarchies, the links between individual emotions and global systems are revealed. The concept of the global intimate challenges the hierarchy of scale that places the body, the home, and the intimate on a much lower level than the scale of the global or the national, and at the same time challenges the binary that divides the individual from the global. Through highlighting the different emotional negotiations that are constantly occurring in the romance tour industry, I highlight the important ways in which individual emotions and affects influence global processes on a large scale and vice versa.

No description available.

This research examines intermediate patterns of joint consumption whereby constellations, anti constellations and configurations are seen as representing patterns of consumption which lie between the traditional micro (product-centred) and macro (societal-centred) studies of consumption. A series of models are developed: of the relationship between individuals and consumption from a social psychological perspective of the formation of patterns of joint consumption and of the three forces which influence patterns of consumption: the symbolic-functional force (located in the product) the physiological-esteem-self-actualization force (located in individual needs) and the expressive-instrumental force (located in activities or behaviour). A two stage empirical study explores the content, structure and context of consumption patterns amongst mail order shoppers in the U.K. The quantitative stage involved the application of correspondence analysis to data extracted from the BMRBffGI database and the qualitative phase was a series of in-depth interviews with mail order industry marketing personnel. The findings confirmed the existence of three identifiable groups amongst mail order shoppers, with different intermediate patterns of joint consumption representing different sets of responses to the three forces which influence consumption and which had been modelled above. The research extends work on the grammar of consumption by developing a set of rules of combination for analyzing the structure and levels of joint consumption: constellations, anti constellations and configurations, which could be associated with the groups of mail order shoppers. The study concludes that products cohere around social roles and that interdependence exists at two levels, firstly, amongst the forces which influence consumption, and secondly, between consumption and the societal-cultural context. It was seen that functional and symbolic complementarities could be found in the intermediate patterns of joint consumption and that different combinatorial rules could be applied to the different levels of consumption patterns elicited for the various groups.