M. Tech. (Department of Business Administration, Faculty of Management Sciences), Vaal University of Technology. / Apart from the contribution and success of the small and medium enterprises (SMEs) through job creation, poverty alleviation and economic growth, there are still organisational factors such as organisational politics and job stress, which hamper the success of these enterprises. The aim of this study was to examine the influence of organisational politics on job stress among SME employees in Matlosana Local District. The target population concentrated on SME employees within Matlosana Local District in North West province, with the population size of N=431 respondents. A quantitative approach was applied, with the use of a cross sectional survey (questionnaire) to gather information on general political behaviour (GB), get ahead (GA), pay and promotion policies (PP), time stress (TS) and anxiety (AX). Data analysis was conducted with the use of the Statistical Package for the Social Sciences (SPSS) version 25.0 and the Analysis of Moment Structures (AMOS) version 25.0. A confirmatory factor analysis (CFA) was applied in examining and testing the relationships between observed constructs and their causal latent constructs while Structural Equation Modelling (SEM) was used to test the hypothesised relationships between constructs. The findings of the study revealed that there is a positive and significant relationship between organisational politics and job stress. The findings also emphasised that organisational politics is considered as a hindrance-related stressor that hampers the proper functioning of individual employees. This study concludes that organisational politics are the social ills of every organisation, it is upon the management of the SMEs to apply good human resource management policies to curb the politics. Contrary, if the organisational politics are not managed well, it will result in impacting the job outcomes such as job stress.