Magister Scientiae Dentium - MSc(Dent) / Previously, many studies have used cone beam computed tomography (CBCT) to detect and confirm the exact location of the MB2 canal in maxillary molars. It is now considered the gold standard, as it allows clinicians to visualize complex anatomical structures and to perform endodontic treatment safely. However, in the context of this study, the prevalence and location of the MB2 in maxillary first and second permanent molars among the Libyan population is limited. The aim of this in vivo study is to describe the prevalence and location of the MB2 in the mesiobuccal root of first and second maxillary molars and to describe a methodology to enable its geometric location in the Libyan population using CBCT imaging.

Orientador: Sérgio Lucio Pereira de Castro Lopes / Resumo: O objetivo deste estudo foi comparar as possíveis alterações em parâmetros geométricos dimensionais das lesões de furca em molares superiores - área máxima de abertura da lesão (AMA), as angulações formadas entre as raízes (ANG), o volume e densidade da lesão (VDL) e a presença e altura de defeitos infraósseos relacionados com a lesão (DIO) – obtidos em imagens por tomografia computadorizada de feixe cônico (TCFC), de pacientes acometidos por periodontite grau C, após a terapia regenerativa com a utilização de proteínas derivadas da matriz do esmalte (EMD). Para tal, foram estudados 02 grupos: controle (cirurgia) (n=17) e grupo teste (cirurgia+EMD) (n=17). Adicionalmente, foi estudada a correlação entre os parâmetros e o sucesso da terapia adotada, avaliando-se a redução da profundidade de sondagem (∆PS) e o ganho do nível de inserção clínica horizontal (∆NICH). Utilizou-se os softwares OnDemand3D (Cybermed, Seul, Coréia do Sul) e itk-SNAP 3.4.0 (University of North Carolina, Chapel Hill, NC, EUA) para avaliação das imagens de TCFC. Para análise das características demográficas foram realizados Teste T, Mann-Whitney Rank Sum Test e Qui-Quadrado, indicando não haver diferenças estatísticas entre idade, número de dentes analisados e sexo (p>0,05). Os testes ANOVA e Teste T foram aplicados no intuito de estudar os parâmetros clínicos (∆PS e ∆NICH) no baseline e após 06 meses de tratamento nos dois grupos, não sendo observadas diferenças estatisticamente significantes entre os gr... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The objective of this study is to compare the possible changes on geometric dimensional parameters of furcation lesions in maxillary molars - maximum area of lesion opening (AMO), angulations formed between roots (ANG), volume and density of the lesion (VDL) and the presence and height of lesion-related infra-osseous defects (DIO) - obtained on cone beam computed tomography (CBCT) images of patients with grade C periodontitis after regenerative therapy using enamel matrix derivative proteins (EMD). To this end, 02 groups were analyzed: control (surgery) (n = 17) and test group (surgery + EMD) (n = 17). Additionally, the correlation between the parameters and the success of the adopted therapy was studied, and the reduction of the depth pocket (ΔPD) and the relative horizontal clinical attachment level (ΔHCAL) were evaluated. Both software OnDemand3D (Cybermed, Seoul, South Korea) and the itk-SNAP 3.4.0 (University of North Carolina, Chapel Hill, NC, USA) were used to evaluate the CBCT images. In order to analyze the demographic characteristics, Mann-Whitney Rank Sum Test and Chi-Square were used, indicating that there were no statistical differences between age, number of teeth analyzed and gender (p> 0.05). The ANOVA and T-tests were applied in order to study the clinical parameters (ΔPD and ΔHCAL) at the baseline and after 06 months of treatment in both groups, no statistically significant differences were observed between the groups in both times (p > 0.05). The Pearson’s ... (Complete abstract click electronic access below) / Mestre