This thesis is an ethnographic study of the present day practice of traditional Chinese herbal medicine by the Chinese community of Vancouver, British Columbia. A qualitative research design was used to document the facilities, activities, people and beliefs involved in the practice of Chinese herbalism. A descriptive survey i s summarized for the 18 herbal pharmacies found in Vancouver's Chinatown. One herbal pharmacy is used as an example to provide a case study for the herbal products available and the interactions between the herbalist and the clientele. The thesis is organized around three key questions. The first concerns the social organization of traditional Chinese herbal knowledge in Vancouver. A tripartite model is used to conceptualize three distinct areas of expertise and knowledge of traditional herbalism in the Chinese community. These are the: (i) traditional Chinese herbal doctors; ( ii ) folk practitioners who are herbal pharmacists; ( iii ) family use of herbs in self-care. A major finding of the study was the central role the Chinese family plays in perpetuating the traditional use of herbs for both the prevention and treatment of disease. The second question attempts to determine how the practice of Chinese herbalism has changed due to its transplantation from Asia to Canada. The most significant difference was the minor role played by the traditional Chinese herbal doctor i n Vancouver compared to those in Hong Kong. The third question the thesis addresses is why "has Chinese herbalism persisted in a Western setting where everyone has free access to a government supported health care system. The author examines both ethnic and cultural explanations to understand the strength of the Chinese herbal tradition in Vancouver. Data on the efficacy of Chinese herbs on both physiological and cultural-symbolic levels is presented to demonstrate the viability of this healing system i n a contemporary context. The thesis concludes with a discussion on the complementarity between the Western and Chinese healing systems from both a practical and a theoretical perspective. / Arts, Faculty of / Anthropology, Department of / Graduate

Indiana University-Purdue University Indianapolis (IUPUI) / Background: The current treatment for HIV/AIDS is called highly active antiretroviral therapy (HAART) and is a combination of anti-HIV reverse transcriptase inhibitors and protease inhibitors. HAART is capable of suppressing HIV replication and subsequently improving the patients’ survival. However, the issues associated with use of HARRT such as the high cost, severe side-effects, and drug resistance have called for development of alternative anti-HIV therapeutic strategies. In this study, we screened several traditional Chinese medicinal herbal extracts for their anti-HIV activities and determined their anti-HIV mechanisms. Methods: Nine traditional Chinese medicinal (TCM) herbal plants and their respective parts derived from Hainan Island, China were extracted using a series of organic solvents, vacuum dried, and dissolved in dimethyl sulfoxide. Initial anti-HIV activity and cytotoxicity of these extracts were evaluated in HIV-infected human CD4+ T lymphocytes Jurkat. Extracts of higher anti-HIV activities and lower cytotoxicity were selected from the initial screening, and further examined for their effects on HIV-1 entry, post-entry, reverse transcriptase, gene transcription and expression using combined virology, cell biology and biochemistry techniques. Results: Four extracts derived from two different herbal plants completely blocked HIV-1 replication and showed little cytotoxicity at a concentration of 10 g/ml. None of these four extracts had any inhibitory effects on HIV-1 long terminal repeat promoter. Two of them exhibited direct inhibitory activity against HIV-1 reverse transcriptase (RT). All four extracts showed significant blocking of HIV-1 entry into target cells. Conclusions: These results demonstrated that four TCM extracts were capable of preventing HIV-1 infection and replication by blocking viral entry and/or directly inhibiting the RT activity. These results suggest the possibility of developing these extracts as potential anti-HIV therapeutic agents.

儒醫是宋以後經過醫學文本訓練的，男性醫者的，文化認同/角色/定位。道醫、巫醫和女性醫者等其他醫者漸成為邊緣他者。儒醫宣稱比其他醫療實踐者更加深諳醫學經典、更加理性。儒醫攀附儒自居，模仿理學門戶互相攻訐，有學派之分。元代婺州朱震亨，「丹溪學派」的創始者，是明代儒醫的典範。本文將以朱震亨和「丹溪學派」為個案，一方面探討儒醫如何建構醫學身體、疾病觀念及其實踐，另一方面探討「丹溪學派」的思想和社會史。 / 第一、二、三章分別從三個角度探討元明儒醫的身體觀。首先，在強烈的「南人」認同之下，元代江浙的士人強調「南/北」身體的差異，「北醫」的療法不適合「南人」的身體，朱震亨被塑造為「南醫」的典範。其次，自劉完素以後，「火」不是日常生活中的火熱之氣，也不是推算運氣的術語，成為元明醫家對身體疾病的想像。據此，朱震亨提出「陽有餘而陰不足」的身體觀，是明代「丹溪學派」遵守的教條。第三，鬼神病因漸漸從儒醫的身體觀中淡出。道教醫學中的「傳尸勞瘵」，混雜了鬼邪和血氣病因，宋元儒醫卻劃分血氣「虛勞」和鬼邪「勞瘵」的界線。朱震亨將「勞瘵」解釋為「陰不足」病。追隨丹溪之後，虞摶病人見鬼實際上是「心神不寧」，清醫吳瑭認為「祝由科」是巫術，儒醫無法容忍鬼邪病因和儀式療法。 / 第四、五章討論儒醫多樣化的實踐。在臨床實踐中如何治療「陰不足」病，「丹溪學派」並不一致，王綸提倡的「補陰丸」在明代江浙醫者的實踐中廣受歡迎，但來自學派內部嚴厲的批評聲同時存在。明代醫家認為唐宋方書治「勞瘵」的天靈蓋「殘忍」，但紫河車卻是明代常用的治療「勞瘵」藥物。儒醫反對儀式療法，但某些驅除鬼邪的針灸療法，改頭換面依然留存在醫學實踐中，比如「秦承祖灸鬼法」。 / 第六、七章指出，從朱震亨到「丹溪學派」，是元代婺州地方士人建設宗族組織、講習理學、建構地方認同背景之下的社會史，也是蘇州城市醫者專業化、組織化的結果。元明政權更迭之後，「丹溪」弟子進入太醫院，依靠政治權威提升「丹溪」的醫學地位。1450年代以後「丹溪」成為商業書坊的暢銷本，注重師承關係的學派逐漸消解，「丹溪」成為大眾通俗的醫學入門文本作者。清代，考據醫學「丹溪」為通俗庸醫，「丹溪」不再是醫者撰寫醫書、醫療實踐的必引權威。 / This thesis aims to explain how Confucian physicians (儒醫) constructed the medical thoughts and practice. A Confucian physician is supposed to be a well-educated gentleman (儒) and a master of the medical classics. From the 12th century on, Confucian physicians gradually became a new identity of the orthodox doctors, while the Taoists, shamans, midwives and surgical practitioners all became the “others. At the same time, among the Confucian Physicians, different schools appeared. The Danxi School (丹溪學派) was a group of disciples following Zhu Zhenheng (朱震亨1282-1358) from the 14th to 15th centuries in Jiangnan (江南) . Zhu was a gentleman from Wuzhou, who was treated as an ideal model of “Confucian physicians through the whole Ming dynasty. / The first three chapters focus on the medical thoughts of Confucian phycians. Chapter One studies on the body of the “Southerners (南人). People living in the territory of Southern Song identified themselves as the “Southerners. This identity was strengthened by the unequal racial policy under the Mongol reign. It motivated the Jiangnan literati to appeal for a medical knowledge body specifically for the “Southerners, which would focus on treating the ailments caused by the “southern environment and dietary habits. Chapter Two explores the concept of “fire. In the Song dynasty, “fire is an element of the prevalent cosmological theory of “the five circulatory phases and the six seasonal influences (五運六氣) . However, in Liu Wansu (劉完素1132-1208) ’s innovative interpretation, the concept of “fire was internalized into the body structure. Zhu Zhenheng inherited this concept of bodily “fire and developed the theory of “yang is always in excess, yin is always deficient (陽有餘而陰不足) , which was later strictly followed by the Danxi School. Chapter Three investigates the disease of “laozhai (勞瘵) . According to the Taoist interpretation, the disease of “laozhai was due to the ancestor’s sin. However, Confucian physicians developed a new meaning in the context of Danxi’s “yin is deficient body. Demons were gradually excluded from the etiology of the Danxi School. / Chapter Four and Five study on the practice of Confucian physicians. The Danxi School didn’t have consensus on how to treat the “yin is deficient disease. Therefore, the therapy of “nourishing yin (滋陰) was quite differential in individual practices. However, it is certain that Confucian physicians tended to use herbs to treat patients who declared themselves suffering from demons. Religious rituals of expelling demons were excluded from their clinical practice. However, Confucian physicians didn’t refuse to use some unusual herbal remedies such as the placenta, or moxibustion that might function as Taoist rituals of expelling demons. / Chapter Six and Seven analyze the rise and fall of the Danxi School. The reason why Zhu became a powerful medical master lies not only in his medical thoughts or skills but in his social activities. He was very active in the lineage organization and local administration. In the local society, Zhu gained the power and fame as an authoritative Confucian gentleman, though he had never received any governmental position. After the death of Zhu, his disciples achieved successful careers as professional doctors in Suzhou (蘇州) . Later when the Ming Empire was established in Nanjing, most of Danxi’s disciples went into the Imperial Medical Service (太醫院) . After the 1450s, Zhu Zhenheng became a best-selling author and a symbol of the popular medicine. The popularity of his works eventually destroyed the structure of the master-disciple relationship in the Danxi School. The Danxi School gradually disappeared. In the end, because the mid-Qing physicians preferred ancient masters such as Zhang Zhongjing (張仲景 fl. 168-196) to the modern, vulgar Danxi, the Danxi School and their medical master faded away from the mainstream medicine. / Detailed summary in vernacular field only. / Detailed summary in vernacular field only. / Detailed summary in vernacular field only. / Detailed summary in vernacular field only. / 張學謙. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2012. / Includes bibliographical references (leaves 197-217). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in Chinese and English. / Zhang Xueqian. / 導論 --- p.1 / Chapter 一、 --- 儒醫：宋元明清醫者的身份認同 --- p.2 / Chapter 二、 --- 儒醫的理性與實踐 --- p.6 / Chapter 三、 --- 丹溪學派：醫學思想的社會史 --- p.11 / Chapter 四、 --- 研究說明 --- p.16 / Chapter 第一章 --- 元代醫學的「南/北」身體觀 --- p.18 / Chapter 一、 --- 南宋和元：「南人」認同的多層含義 --- p.18 / Chapter 二、 --- 「南/北」身體觀論述 --- p.24 / Chapter 三、 --- 製造「南醫」/「北醫」 --- p.32 / Chapter 四、 --- 結論 --- p.38 / Chapter 第二章 --- 丹溪學派的口號：「陽有餘而陰不足」的身體觀 --- p.40 / Chapter 一、 --- 五運六氣與宋人的身體觀 --- p.40 / Chapter 二、 --- 內丹對醫學身體觀的影響 --- p.46 / Chapter 三、 --- 朱震亨的相火論 --- p.50 / Chapter 四、 --- 結論 --- p.59 / Chapter 第三章 --- 宋明儒醫的「理性化」：以「勞瘵」為中心 --- p.60 / Chapter 一、 --- 《道藏》文本中「勞瘵」的界定 --- p.62 / Chapter 二、 --- 儒醫文本中「勞瘵」的界定 --- p.68 / Chapter 三、 --- 儒醫「勞瘵」與明代社會身體 --- p.73 / Chapter 四、 --- 明代儒醫對「祝由」的困惑 --- p.77 / Chapter 五、 --- 結論 --- p.85 / Chapter 第四章 --- 「陰虛」病與療法 --- p.87 / Chapter 一、 --- 丹溪「陰虛」病及療法 --- p.87 / Chapter 二、 --- 補陰丸與人參之爭 --- p.93 / Chapter 三、 --- 薛己、趙獻可：從補陰血到補陰精 --- p.99 / Chapter 四、 --- 結論 --- p.103 / Chapter 第五章 --- 儒醫的實踐 --- p.105 / Chapter 一、 --- 道醫「追蟲」儀式 --- p.105 / Chapter 二、 --- 儒醫勞瘵療法 --- p.108 / Chapter 三、 --- 天靈蓋與紫河車在明代醫學中的不同遭遇 --- p.113 / Chapter 四、 --- 從「秦承祖灸鬼法」到「灸鬼哭穴」 --- p.121 / Chapter 五、 --- 結論 --- p.125 / Chapter 第六章 --- 從朱震亨到「丹溪學派」的社會史 --- p.126 / Chapter 一、 --- 朱震亨的出身與赤岸朱氏宗族的建構 --- p.129 / Chapter 二、 --- 「儒醫」朱震亨與地方社會 --- p.136 / Chapter （一） --- 朱震亨之行醫 --- p.137 / Chapter （二） --- 朱震亨之醫療產業 --- p.140 / Chapter （三） --- 朱震亨在地方社會的角色 --- p.142 / Chapter 三、 --- 元代婺州的「丹溪」門徒 --- p.147 / Chapter （一） --- 地方醫療資源與組織 --- p.147 / Chapter （二） --- 婺州地方士族的網絡 --- p.151 / Chapter 四、 --- 元末蘇州的「丹溪」門徒 --- p.155 / Chapter 五、 --- 明代太醫院的「丹溪」門徒（1368-1450） --- p.162 / Chapter 六、 --- 結論： --- p.166 / Chapter 第七章 --- 「丹溪」的大眾化與清代醫學的轉折 --- p.167 / Chapter 一、 --- 「丹溪」文本的製造與流傳 --- p.168 / Chapter （一） --- 「丹溪」文本的製造 --- p.168 / Chapter （二） --- 「丹溪」文本的印刷與晚明私人的商業書坊 --- p.178 / Chapter 二、 --- 「丹溪」權威的下降 --- p.183 / Chapter （一） --- 明清醫者對「南/北」身體觀、療法的不同意見 --- p.184 / Chapter （二） --- 「陰不足」到「命門火衰」 --- p.186 / Chapter （三） --- 考據醫學之批評「丹溪」 --- p.188 / Chapter 三、 --- 結論 --- p.192 / 結論 --- p.193 / 參考書目 --- p.197 / Chapter 一、 --- 一手文獻 --- p.197 / Chapter (一) --- 醫書 --- p.197 / Chapter (二) --- 正史 --- p.200 / Chapter (三) --- 文集 --- p.201 / Chapter (四) --- 地方志和家譜 --- p.203 / Chapter (五) --- 筆記和其他： --- p.204 / Chapter 二、 --- 工具書： --- p.206 / Chapter 三、 --- 近人研究： --- p.207 / Chapter (一) --- 中文專書 --- p.207 / Chapter (二) --- 英文專書 --- p.209 / Chapter (三) --- 中文論文 --- p.212 / Chapter (四) --- 英文論文 --- p.214

Halenia elliptica D. Don belongs to Gentianaceae family. It is often used as part of a traditional Tibetan medicine to treat hepatitis. In the present investigation, six major xanthone components were isolated and identified from Halenia elliptica. An HPLC/DAD/APCI/MS method was developed and validated for the quantitative analysis of these xanthones, including 1-hydroxy-2,3,5-trimethoxy-xanthone (HM-1), 1-hydroxy-2,3,4,7-tetramethoxy- xanthone (HM-2), 1-hydroxy-2,3,4,5-tetramethoxy-xanthone (HM-3), 1,7- dihydroxy-2,3,4,5-tetramethoxy-xanthone (HM-4), 1,5-dihydroxy-2,3-dimethoxy-xanthone (HM-5) and 1-0-[beta-D-xylopyranosyl-(1-6)-beta-D-glucopyranosyl]-2,3,5-trimethoxy-xanthone (HM-2-10). All the xanthones aglycons caused vasodilation in the coronary artery pre-contracted with 1 muM 5-HT, but the xanthone glycoside had no effect. HM-1 was one of the most abundant xanthones with the most potent vasorelaxant activity. / Mechanisms of the vasorelaxant effect of HM-1 were investigated. HM-1 showed a potent vasorelaxant activity on rat coronary artery involved both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca2+ influx through L-type voltage-operated Ca2+ channels. / Taken together, in spite of the pharmacokinetics results showed that HM-1 was rapidly and widely distributed to tissues after intravenous administration in rats, with conjugation to being the major metabolic pathway in vivo, both HM-1 and its active metabolite (HM-5) show that they are important pharmacological agents with potentially useful therapeutic indications. / The metabolism and pharmacokinetics of HM-1 displayed biphasic elimination kinetics, with an elimination half-life of 60.4 +/- 4.2 min. Four other Phase I metabolites were isolated and identified as demethylated products in vitro. HM-1 was metabolised to HM-5 in the liver. Biliary excretion studies showed that both HM-1 and the metabolite (HM-5) underwent extensive phase II conjugation to form glucuronides and sulfates. Tissue distribution studies showed that HM-1 was widely distributed to different organs. Collection of urine and faeces over 24 h showed that 10.88% of dose was excreted from urine and 1.91% of dose via faeces. / With HM-5 being one of the major in vivo metabolites of HM-1, the effect of HM-5 has been studied on rat coronary artery and compared to HM-1. HM-5-mediated vasorelaxant effect was mediated through opening of potassium channel (TEA, 4-AP) and altering intracellular calcium by partial inhibition of Ca2+ influx through L-type voltage-operated Ca 2+ channels and intracellular Ca2+ stores. / "September 2007." / Source: Dissertation Abstracts International, Volume: 69-08, Section: B, page: 4699. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2007. / Includes bibliographical references (p. 195-218). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in English and Chinese. / School code: 1307.

by Cheung Chi-kong, Chu Hok-keung, Ting Wai-tong. / Thesis (M.B.A.)--Chinese University of Hong Kong, 1990. / Bibliography: leaf 83. / Chapter I. --- BACKGROUND --- p.1 / Introduction --- p.1 / The Origin of Chinese Medicine --- p.2 / A Definition of Chinese Medicine --- p.5 / A Survey --- p.6 / Chapter II. --- LITERATURE REVIEW --- p.7 / Chapter III. --- METHODOLOGY --- p.14 / Data Sources --- p.14 / Sample Design --- p.15 / Data Processing --- p.16 / Chapter IV. --- FINDINGS FROM THE STUDY --- p.17 / Chinese Herbal Drugs --- p.17 / Chinese Health Foods --- p.23 / Further Analysis --- p.29 / Chapter V. --- SUMMARY AND RECOMMENDATIONS --- p.37 / Summary --- p.37 / Chinese Herbal Drugs : Recommendations --- p.39 / Chinese Health Foods : Recommendations --- p.52 / APPENDIX --- p.65 / Profiles of Respondents --- p.65 / Questionnaire (English/Chinese Version) --- p.68 / BIBLIOGRAPHY --- p.83

本文回顧了前近代時期中國傳統婦產科一門的醫學沿革與歐美產科醫學的「現代化」過程，追溯了西方婦產醫學自19世紀中期以來傳入廣州的發展軌跡。同時將目光聚焦於傳統醫學與19世紀傳入廣州的西方醫學，並將兩種體系進行比較。發現在不同的情況下二者表現出不同的利弊，無法評價其各自方法之優劣。而由傳教士所帶來的西法接生因為其統一、規範的操作被務實的廣州人所接受，並被善堂採用而作為慈善服務的一種，從而在廣州傳播並得到普及。可見，在廣州的西化過程中，是國人將適合自身的西方事物融入到本地社會生活中，並在不斷的磨合中完成「現代化」，而非國人克服種種困難，不斷地追求科學等現代指標。 / 此外，本文描繪廣州社會在20世紀初期接納「西法接生」，並將其作為一種摩登的接生方法而運用的歷史。受教會訓練的「女醫生」已成為一種正當的職業在社會上存在，「西法接生」這種由西醫外科衍變而來的技術為女醫生所利用，成為她們執業的亮點。通過善堂的贈接生善舉，「西法接生」在廣州的認知度得以提升，直至政府將婦女生產納入其衛生行政體系，並對接生從業者加以規管。可見，廣州婦女分娩的「現代化」並非得力於政府衛生行政的推動，而是在更早時期自發出現的。 / 通過比較香港、北京、廣州、上海四地政府對助產人員的規管條例，不同城市顯示出各自的特色。北京、上海借助西方公共衛生行政管理方法，集中對產婆進行培訓、登記，使其接生操作符合衛生行政要求，從而建立出一套適應中國社情的混合式制度，並以這一模式進行婦女生產的「現代化」。在中國醫療西化的過程中，不同的地方社會有著不同的衛生行政管理軌跡。 / This article examines the introduction, development, and proliferation of western Obstetrics, in particular the Midwifery, in Canton from 1860s to 1930s. By comparing and contrasting treatment of childbirth by traditional Chinese Midwifery in pre-modern period, especially the Ming and Qing Dynasties to the Western Midwifery brought to Canton in this period, it is concluded that, subscribed to each distinctive medical theories, the two applied different views and strategies on the course of childbirth. Nevertheless, from an overall perspective, western Midwifery didn’t display obvious advantages compared with the Chinese traditional one. During the period of 1890s and 1920s, local philanthropic organizations actively promoted the approach and benefits of western midwifery to the local community to the childbirth modernity. / In addition, the modernization on childbirth in Canton was different to which in Beijing, Shanghai and Hong Kong. In Beijing and Shanghai, the Municipal Governments established a new blended system legislating the centralized training and registration of traditional midwives to archive childbirth modernization with the application of western public health methods. In Canton, on the contrary, a large number of young women who have had more systematic classes and professional western medical training actively in missionary or local medical schools, became so-called “Obstetrics doctors. They participated in the “Free Delivery service offered by local philanthropic organizations with their western midwifery skills as a selling point, and replaced the traditional midwives to obtaining the majority of midwives. This led to another path to childbirth modernization. / It was suggested that different areas of China progressed variously during the journey of medical modernization and Canton played the unique role in the medical modernization of China. / Detailed summary in vernacular field only. / Detailed summary in vernacular field only. / Detailed summary in vernacular field only. / 蔡笳. / "2012年8月". / "2012 nian 8 yue". / Thesis (M.Phil.)--Chinese University of Hong Kong, 2012. / Includes bibliographical references (leaves 89-95). / Abstract in Chinese and English. / Cai Jia. / 摘要 --- p.i / 目錄 --- p.iii / 導論 --- p.1 / Chapter 一、 --- 19、 20世紀中國的「現代化」問題 --- p.1 / Chapter 二、 --- 醫療史與中國「現代化」問題的討論 --- p.3 / Chapter 三、 --- 女性生育與醫療 --- p.4 / Chapter 四、 --- 廣州與中國「現代化」的地區差異 --- p.6 / Chapter 五、 --- 章節結構 --- p.8 / Chapter 第一章 --- 明清中國產科與17-19世紀的西方產科 --- p.9 / Chapter 一、 --- 明代以前中國的婦產醫學 --- p.10 / Chapter 二、 --- 明清以來中國婦產醫學與生育習俗 --- p.11 / Chapter （一） --- 明清時期中國婦產醫學 --- p.11 / Chapter （二） --- 明清時期的分娩處理 --- p.12 / Chapter 三、 --- 18、 19世紀歐美產科醫學的發展 --- p.18 / Chapter （一） --- 英國產科醫學的概況 --- p.18 / Chapter （二） --- 現代醫學的產生與婦產科之變化 --- p.20 / Chapter （三） --- 18、 19世紀的美國產科發展 --- p.21 / Chapter 四、 --- 小結 --- p.22 / Chapter 第二章 --- 西醫產科傳入廣州（1834-1890） --- p.25 / Chapter 一、 --- 西醫產科的早期發展 --- p.25 / Chapter （一） --- 伯駕的到來（1834-1850） --- p.25 / Chapter （二） --- 嘉約翰的成就：西醫醫院的雛形和西醫教育（1855-1899） --- p.27 / Chapter 二、 --- 女傳教士醫生的到來和西醫婦產醫療的實踐 --- p.32 / Chapter 三、 --- 女醫學堂的緣起 --- p.35 / Chapter 四、 --- 女醫學堂的醫學教育 --- p.37 / Chapter （一） --- 教育培訓 --- p.37 / Chapter （二） --- 西醫助產方法操作規範 --- p.40 / Chapter （三） --- 備用器材 --- p.44 / Chapter 五、 --- 夏葛醫校與柔濟醫院的婦產醫療實踐 --- p.44 / Chapter 六、 --- 小結 --- p.45 / Chapter 第三章 --- 西醫婦產在當地社會的發展（1895-1930） --- p.47 / Chapter 一、 --- 清末民初廣州善堂的「贈接生」服務 --- p.47 / Chapter （一） --- 順德水藤如春善社與廣州贊育醫社 --- p.49 / Chapter （二） --- 廣州方便醫院 --- p.50 / Chapter 二、 --- 清末民初產科醫院的創立 --- p.53 / Chapter 三、 --- 廣州婦產醫生群體 --- p.55 / Chapter （一） --- 出身背景 --- p.56 / Chapter （二） --- 女性產科師在醫患關係中的角色 --- p.57 / Chapter 四、 --- 政府衛生行政對產科從業者之規管 --- p.59 / Chapter 五、 --- 小結 --- p.68 / 結論 --- p.69 / 附錄 --- p.75 / 參考書目 --- p.89

Woo Yiu Ho Anthony. / "August 2004." / Thesis (Ph.D.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references (p. 176-198). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.

Human viral infections are important health problem worldwide. Although much effort has been made, antiviral drugs, because of the unique properties of viruses, are relatively fewer in number and possess relatively narrow spectrum of activities as compared with antibiotics. Moreover, efficacy, drug resistance and side effect are the problems of antiviral drugs in clinical uses. Thus, it is necessary to develop new, effective and safe antiviral drug. / Thirty-seven medicinal herbs, which were collected from Guangdong province or the Hong Kong region, were selected to screen for their antiviral activities against HSV-1 and/or RSV in vitro using a cytopathic effect (CPE) reduction assay. The selection of the herbs was mainly based on their traditional use in the treatment of human infectious diseases of the skin and respiratory tract. / Three of 37 medicinal herbs, Agrimonia pilosa, Pithecellobium clypearia, and Punica granatum, showed anti-HSV-1 activity, which was possibly contributed from polyphenolic compounds in the herbal extracts. Six of 21 medicinal herbs, Blumea laciniata, Elephantopus scaber, Laggera pterodonta, Mussaenda pubescens, Schefflera heptaphylla, and Scutellaria indica, exhibited potent anti-RSV activity with 50% inhibition concentrations (IC50) ranging from 12.5 to 32 mug/ml, and the selective indices (SI) ranging from 11.2 to 40. Moreover, the anti-RSV SI values of Laggera pterodonta and Schefflera heptaphylla were found to be higher than that of ribavirin. Finally, Schefflera heptaphylla having the highest anti-RSV SI value among the active herbs was subjected to further study its antiviral activity. (Abstract shortened by UMI.) / Traditional herbal medicines have been used for a long time in the treatment of human infectious diseases in many countries, including China. Antiviral screening has shown that quite a few medicinal herbs distributed in various regions of the world possess significant antiviral activities with no or limited adverse effects, and many naturally occurring compounds exhibit antiviral activity in vitro and/or in vivo. In the present study, our objectives are to (1) screen for potential antiviral agents from selected herbal medicines traditionally used in southern China, (2) isolate and characterize the antiviral constituents from the most active herb, and (3) probe possible antiviral modes of action of the active compounds. The viruses used in the present study included respiratory syncytial virus (RSV), herpes simplex virus type 1 (HSV-1), influenza A virus (Flu A), and coxsackie B3 virus (Cox B3). However, the present study mainly focused on searching for anti-RSV and anti-HSV-1 agents from selected Chinese herbal medicines. / Li Yaolan. / "October 2004." / Source: Dissertation Abstracts International, Volume: 66-07, Section: B, page: 3506. / Supervisors: Vincent V. E. C. Ooi; Paul P. H. But. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references (p. 160-178). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in English and Chinese. / School code: 1307.

Ling, Ka Ho. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2008. / Includes bibliographical references (leaves 124-157). / Abstracts in English and Chinese. / Acknowledgement --- p.ii / Abstract --- p.iv / 摘要 --- p.vii / Table of content --- p.ix / List of figures --- p.xiii / List of tables --- p.xv / Abbreviations --- p.xvi / Chapter 1 --- Food authentication --- p.1 / Chapter 1.1 --- Introduction and definition --- p.1 / Chapter 1.2 --- Importance of species identification in food authentication --- p.3 / Chapter 1.3 --- Methods for species identification in food authentication --- p.8 / Chapter 1.4 --- Legislation --- p.17 / Chapter 1.5 --- Objectives --- p.19 / Chapter 2 --- Molecular authentication and antitussive bioassay of Stemona root (Baibu) and root of Asparagus filicinus (Xiao-baibu) --- p.20 / Chapter 2.1 --- Introduction --- p.20 / Chapter 2.2 --- Materials and methods --- p.22 / Chapter 2.3 --- Results --- p.34 / Chapter 2.4 --- Discussion --- p.40 / Chapter 2.5 --- Conclusions --- p.44 / Chapter 3 --- Rapid detection of oilfish and escolar in fish steaks: a tool to prevent keriorrhea episodes --- p.45 / Chapter 3.1 --- Introduction --- p.45 / Chapter 3.2 --- Materials and methods --- p.49 / Chapter 3.3 --- Results --- p.59 / Chapter 3.4 --- Discussion --- p.69 / Chapter 3.5 --- Conclusions --- p.75 / Chapter 4 --- Widespread adulteration of crocodile meat with python and water monitor meats --- p.76 / Chapter 4.1 --- Introduction --- p.76 / Chapter 4.2 --- Materials and methods --- p.78 / Chapter 4.3 --- Results --- p.89 / Chapter 4.4 --- Discussion --- p.96 / Chapter 4.5 --- Conclusions --- p.100 / Chapter 5 --- Authentication of dried and ready-to-eat hashima products --- p.101 / Chapter 5.1 --- Introduction --- p.101 / Chapter 5.2 --- Source species of hashima --- p.103 / Chapter 5.3 --- Materials and methods --- p.106 / Chapter 5.4 --- Results --- p.116 / Chapter 5.5 --- Discussion --- p.119 / Chapter 5.6 --- Conclusions --- p.121 / Chapter 6 --- General conclusions --- p.122 / Chapter 6.1 --- Key findings --- p.122 / Chapter 6.2 --- Applications and implications --- p.123 / Chapter 7 --- References --- p.124

Cheung, Chun Wai. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2007. / Includes bibliographical references (leaves 111-128). / Abstracts in English and Chinese. / Acknowledgement --- p.ii / Abstract --- p.iv / 摘要 --- p.vii / Table of content --- p.ix / List of Figures --- p.xvii / List of Tables --- p.xix / Abbreviations --- p.xxi / Chapter Chapter 1. --- Introduction --- p.1 / Chapter 1.1 --- Complementary and Alternative Medicine (CAM) and Traditional Chinese Medicine (TCM) --- p.1 / Chapter 1.2 --- The development of Traditional Chinese Medicine --- p.2 / Chapter 1.3 --- Quality control of Traditional Chinese Medicine --- p.3 / Chapter 1.4 --- Problems of adulteration --- p.5 / Chapter 1.4.1 --- Confusion by common names --- p.5 / Chapter 1.4.2 --- Erroneous and intentional adulteration --- p.6 / Chapter 1.5 --- Authentication of Traditional Chinese Medicine using DNA techniques --- p.7 / Chapter 1.6 --- Crocodile meat --- p.10 / Chapter 1.6.1 --- Crocodile meat as Traditional Chinese Medicine --- p.10 / Chapter 1.6.2 --- Crocodile meat as exotic meat --- p.10 / Chapter 1.6.3 --- Effects of crocodile meat on mice --- p.12 / Chapter 1.6.4 --- Adulteration of crocodile meat in Hong Kong --- p.13 / Chapter 1.6.5 --- Authentication of crocodile meat --- p.14 / Chapter 1.6.5.1 --- SCAR analysis --- p.14 / Chapter 1.6.5.2 --- 12S and 16S ribosomal DNA --- p.14 / Chapter 1.7 --- Fish air-bladder --- p.15 / Chapter 1.7.1 --- Fish air-bladder as Traditional Chinese Medicine --- p.15 / Chapter 1.7.2 --- A case study --- p.16 / Chapter 1.7.3 --- Authentication of fish air-bladder --- p.17 / Chapter 1.8 --- Radix Stellariae --- p.18 / Chapter 1.8.1 --- Stellaria dichotoma L. var. lanceolata Bge --- p.18 / Chapter 1.8.2 --- Radix Stellariae as Traditional Chinese Medicine --- p.19 / Chapter 1.8.3 --- Chemicals in Radix Stellariae and their uses --- p.19 / Chapter 1.8.4 --- Adulteration of Radix Stellariae --- p.20 / Chapter 1.8.5 --- Authentication of Radix Stellariae --- p.21 / Chapter 1.8.5.1 --- Internal Transcribed Spacers (ITS) --- p.21 / Chapter 1.8.5.2 --- trnH-psbA intergenic spacer --- p.23 / Chapter 1.9 --- Objectives --- p.25 / Chapter Chapter 2. --- Materials and Methods --- p.26 / Chapter 2.1 --- Samples used in the study --- p.26 / Chapter 2.1.1 --- Crocodile and monitor lizard samples --- p.26 / Chapter 2.1.2 --- Sequence from NCBI database --- p.26 / Chapter 2.1.3 --- Fish air-bladder samples --- p.30 / Chapter 2.1.4 --- Radix Stellariae samples and samples of related species --- p.33 / Chapter 2.1.5 --- Sequences from NCBI database --- p.33 / Chapter 2.2 --- Reagents and equipments --- p.36 / Chapter 2.2.1 --- Sample preparation and DNA extraction --- p.36 / Chapter 2.2.2 --- Polymerase Chain Reaction --- p.38 / Chapter 2.2.3 --- Agarose gel electrophoresis and Gene Clean --- p.39 / Chapter 2.2.4 --- Cloning --- p.40 / Chapter 2.2.5 --- Cycle sequencing --- p.41 / Chapter 2.3 --- Experimental procedures --- p.42 / Chapter 2.3.1 --- Sample preparation --- p.42 / Chapter 2.3.2 --- DNA extraction --- p.42 / Chapter 2.3.3 --- Polymerase Chain Reaction --- p.44 / Chapter 2.3.4 --- Agarose gel electrophoresis --- p.47 / Chapter 2.3.5 --- Gene Clean --- p.47 / Chapter 2.3.6 --- Cloning --- p.48 / Chapter 2.3.7 --- Cycle sequencing and sequence analyses --- p.51 / Chapter Chapter 3. --- Crocodile meat - Results and Discussion --- p.54 / Chapter 3.1 --- Results --- p.54 / Chapter 3.1.1 --- SCAR analysis --- p.54 / Chapter 3.1.2 --- Sequence analyses --- p.55 / Chapter 3.1.3 --- The dendrograms --- p.56 / Chapter 3.2 --- Discussion --- p.60 / Chapter 3.2.1 --- SCAR as a quick and inexpensive method for the authentication of crocodile meat --- p.60 / Chapter 3.2.2 --- DNA sequencing - A useful tool to identify the source species of the crocodile meat --- p.61 / Chapter 3.2.3 --- Adulteration of crocodile meat in Hong Kong --- p.63 / Chapter 3.2.4 --- Source species of the genuine crocodile meats and the adulterants --- p.63 / Chapter 3.2.5 --- Regulation of labeling of food in Hong Kong --- p.69 / Chapter 3.2.6 --- Source species of the lizard head and tail from AFCD --- p.69 / Chapter 3.3 --- Summary --- p.70 / Chapter Chapter 4. --- Fish air-bladders - Results and Discussion --- p.72 / Chapter 4.1 --- Results --- p.72 / Chapter 4.1.1 --- Identities of sample BH and F1 --- p.73 / Chapter 4.1.2 --- Identity of sample BS --- p.74 / Chapter 4.1.3 --- Identities of samples GD and ZG --- p.74 / Chapter 4.1.4 --- Identity of sample GG --- p.74 / Chapter 4.1.5 --- "Identities of samples HB, HT and SH" --- p.75 / Chapter 4.1.6 --- Identity of sample JL --- p.75 / Chapter 4.1.7 --- Identity of sample MS --- p.76 / Chapter 4.1.8 --- Identity of sample RE --- p.76 / Chapter 4.2 --- Discussion --- p.77 / Chapter 4.2.1 --- Sample RE was confirmed to have originated from rabbit ears --- p.77 / Chapter 4.2.2 --- Identities of the dry fish air-bladders sold in Hong Kong --- p.79 / Chapter 4.2.3 --- Identities of the fresh fish air-bladders sold in Hong Kong --- p.82 / Chapter 4.2.4 --- Limitations of the use of DNA sequences for source species identification --- p.83 / Chapter 4.2.5 --- Variation in prices of fish air-bladders --- p.87 / Chapter 4.3 --- Summary --- p.88 / Chapter Chapter 5. --- Radix Stellariae - Results and Discussion --- p.89 / Chapter 5.1 --- Results --- p.89 / Chapter 5.1.1 --- Sequence analyses --- p.90 / Chapter 5.1.2 --- The dendrograms --- p.90 / Chapter 5.2 --- Discussion --- p.97 / Chapter 5.2.1 --- Identities of the samples obtained from the market --- p.97 / Chapter 5.2.2 --- Identity of sample Sdl4 --- p.97 / Chapter 5.2.3 --- Identities of samples Sd02R and Sd04 --- p.100 / Chapter 5.2.4 --- Myosoton aquaticum in the Stellaria-Myosoton clade --- p.104 / Chapter 5.2.5 --- Medicinal uses of the substitutes of Radix Stellariae --- p.105 / Chapter 5.3 --- Summary --- p.106 / Chapter Chapter 6. --- Conclusion --- p.107 / Reference --- p.111 / Appendix 1. 12S rDNA sequences of crocodilian and Varanus species obtained from NCBI database for sequence analyses --- p.129 / Appendix 2. 16S rDNA sequences of crocodilian and Varanus species obtained from NCBI database for sequence analyses --- p.130 / "Appendix 3. ITS sequences of the species in the genera Arenaria, Myosoton, Silene, and Stellaria obtained from NCBI database for sequence analyses" --- p.131 / Appendix 4. 7rnH-psbA intergenic spacer sequences of Silene species obtained from NCBI database for sequence analyses --- p.132 / Appendix 5. Sequence alignment of 12S rRNA gene sequences of crocodile and monitor lizard samples --- p.133 / Appendix 6. Sequence alignment of 16S rRNA gene sequences of crocodile and lizard samples --- p.141 / Appendix 7. Sequence alignment of coxl sequences of fish air-bladder samples --- p.149 / Appendix 8. Sequence alignment of 12S rRNA gene sequences of fish air-bladder samples --- p.151 / Appendix 9. Sequence alignment of 16S rRNA gene sequences of fish air-bladder samples --- p.153 / Appendix 10. Sequence alignment of coxl region of Vibrio parahaemolyticus and the coxl primers --- p.155 / Appendix 11. Sequence alignment of ITS sequences of Radix Stellariae and related samples --- p.156 / Appendix 12. Sequence alignment of trnH-psbA of Radix Stellariae and related samples --- p.163 / Appendix 13. Search results of coxl sequences of the fish air-bladder samples in BOLD-IDS --- p.167 / Appendix 14. Search results of coxl sequences of the fish air-bladder samples in NCBI nucleotide BLAST --- p.168 / Appendix 15. Search results of 12S rDNA sequences of the fish air-bladder samples in NCBI nucleotide BLAST --- p.169 / Appendix 16. Search results of 16S rDNA sequences of the fish air-bladder samples in NCBI nucleotide BLAST --- p.170 / Appendix 17. Sequence similarities (%) of coxl sequences of the fish air-bladder samples --- p.171 / Appendix 18. Sequence similarities (%) of 12S rDNA sequences of the fish air-bladder samples --- p.172 / Appendix 19. Sequence similarities (%) of 16S rDNA sequences of the fish air-bladder samples --- p.173