Wong, Tsz-wai, Terence., 黃子維.
The exponential expansion in the field of biophotonics over the past half-century has been leading to ubiquitous basic science investigations, ranging from single cell to brain networking analysis. There is also one biophotonics technology used in clinic, which is optical coherence tomography, mostly for high-speed and high-resolution endoscopy. To keep up such momentum, new biophotonics technologies should be aiming at improving either the spatial resolution or temporal resolution of optical imaging. To this end, this thesis will address a new imaging technique which has an ultra-high temporal resolution. The applications and its cost-effective implementations will also be encompassed. In the first part, I will introduce an entirely new optical imaging modality coined as optical time-stretch microscopy. This technology allows ultra-fast real-time imaging capability with an unprecedented line-scan rate (~10 million frames per second). This ultrafast microscope is renowned as the world’s fastest camera. However, this imaging system is previously not specially designed for biophotonics applications. Through the endeavors of our group, we are able to demonstrate this optical time-stretch microscopy for biomedical applications with less biomolecules absorption and higher diffraction limited resolution (<2 μm). This ultrafast imaging technique is particularly useful for high-throughput and high-accuracy cells/drugs screening applications, such as imaging flow cytometry and emulsion encapsulated drugs imaging. In the second part, two cost-effective approaches for implementing optical time-stretch confocal microscopy are discussed in details. We experimentally demonstrate that even if we employ the two cost-effective approaches simultaneously, the images share comparable image quality to that of captured by costly specialty 1μm fiber and high-speed ( >16 GHz bandwidth) digitizer. In other words, the cost is drastically reduced while we can preserve similar image quality. At the end, I will be wrapping up my thesis by concluding all my work done and forecasting the future challenges concerning the development of optical time-stretch microscopy. In particular, three different research directions are discussed. / published_or_final_version / Electrical and Electronic Engineering / Master / Master of Philosophy
Eigenbrot, Ilya Vladimirovich
No description available.
Characterizing cavity containing materials using electron microscopy : A study of metal oxides, mesoporous crystals and porous material containing nanosized metal-particlesKlingstedt, Miia January 2011 (has links)
This thesis concerns the characterization of novel materials by utilizing electron microscopy techniques. The examined materials contain cavities with certain attributes that enables desired properties for applications such as gas separation, catalysis and fuel cells. The specimens concerned herein belong to the following groups of materials: Metal oxides in the Sb-W-Mo-O system; ordered mesoporous silicas and carbons; hollow spheres containing Au-nanoparticles; zeolite LTA incorporated with mesopores; metal organic frameworks doped with nickel. With scanning electron microscopy (SEM) and transmission electron microscopy (TEM) you get vast possibilities within the field of characterization. This thesis utilizes conventional electron microscopy techniques such as imaging, energy-dispersive spectroscopy and electron diffraction as well as reconstruction techniques, such as exit-wave reconstruction, electron tomography and electron crystallography. Furthermore, the sample preparation technique cross-section polishing has been used in conjunction with low voltage SEM studies. The scientific approach is to gain knowledge of nano-sized cavities in materials, in particular their shape, size and content. The cavities often have irregularities that originates from the synthesis procedure. In order to refine the synthesis and to understand the properties of the material it is required to carefully examine the local variations. Therefore average characterization techniques such as crystallography needs to be combined with local examination techniques such as tomography. However, some of the materials are troublesome to investigate since they to some extent bring limitations to or gets easily damaged by the applied characterization technique. For the development of novel materials it is essential to find means of overcoming also these obstacles. / At the time of the doctoral defense, the following paper was unpublished and had a status as follows: Paper 6: Submitted.
Thesis (M.S.)--University of Delaware, 2009. / Principal faculty advisor: Gonzalo Arce, Dept. of Electrical & Computer Engineering. Includes bibliographical references.
Swisher, Douglas Lee.
(has links) (PDF)
Thesis (Ph. D. in Mechanical Engineering)--Naval Postgraduate School, March 2003. / Dissertation supervisor: T.R. McNelley. Includes bibliographical references (p. 152-166). Also available online.
Thesis (Ph. D.)--University of Wisconsin--Madison, 1985. / Typescript. Vita. Includes bibliographical references (leaves 268-283).
Kutscha, Norman P.
Thesis (M.S.)--University of Wisconsin, 1961. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 148-150).
Wentworth, Guillermo H.
Design, development, and application of an automated precision scanning microscope stage with a controlled environmentWright, Adele Hart 05 1900 (has links)
No description available.
Manhart, Paul Kenneth.
No description available.
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