Global ETD Search

111	Cloning and characterization of novel IgA antibody variable heavy and light chains from HIV-1 resistant sex workers from Nairobi, Kenya Sarna, Caitlin S. 14 April 2011 (has links) Heterosexual intercourse now accounts for the majority of HIV transmission within sub-Saharan Africa. The generation of microbicides and vaccines, therefore, requires a better understanding of the mucosal correlates of protection, including the role of HIV-specific IgA. It is now accepted that not all individuals are equally susceptible to HIV-1 infection, as exemplified by the HIV Exposed Seronegative (HESN) women of the Pumwani Cohort in Nairobi, Kenya. To assess whether mucosal IgA responses contribute to this protection, 3 novel IgA variable genes were cloned from HESN cervical B-cell cDNA. Nine monoclonal IgA Abs were produced, two of which were properly produced from cell culture. The HESN-derived A6/30L and A9/30L variants had a greater specificity for gp120IIIB than their A6/4L and A9/4L counterparts, while the A6 variant recognizes a distinct gp120 epitope compared to the broadly neutralizing antibody IgGb12. Further characterization of these IgA chains may suggest their suitability for use in microbicides or mucosal vaccines. IgA HIV-1 gp120 Monoclonal antibodies HESN Mucosal immunology
112	Immunosuppression with monoclonal antibodies in neural transplantation Honey, C. R. January 1990 (has links) No description available. 590
113	Studies on the functional heterogeneity of rat T cells using monoclonal antibodies Spickett, Gavin January 1983 (has links) No description available. 572.8
114	Engineered Antibodies. Production and application of chimeric and single-chain antibodies as positive controls in the diagnosis of infectious diseases by ELISA. Jones, Martina Unknown Date (has links) No description available.
115	Analysis of acute mycloid leukaemia cell surface antigens with monoclonal antibodies / Gadd, Stephen J. January 1985 (has links) (PDF) Thesis (Ph. D.)--University of Adelaide, 1985. / Includes bibliographical references (leaves 129-145).
116	Studies of the hepatitis C virus envelope proteins : interaction with host cells and as targets for the humoral response / Beyene, Aster, January 2004 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 5 uppsatser.
117	Characterization of an acanthamoeba castellanii adhesin Kennett, Mary J. January 1999 (has links) Thesis (Ph. D.)--University of Missouri--Columbia, 1999. / Typescript. Vita. Includes bibliographical references (leaves 117-128). Also available on the Internet.
118	Site-directed in vitro immunization a model of sequential antigen-specific activation of human B cells / Chin, Li-Te. January 1994 (has links) Thesis (doctoral)--Lund University, 1994. / Added t.p. with thesis statement inserted.
119	Mass transfer, mixing, Chinese hamster ovary cell growth and antibody production characterization using Rushton turbine and marine impellars Sandadi, Sandeep. January 2009 (has links) Thesis (Ph. D.)--Rutgers University, 2009. / "Graduate Program in Chemical and Biochemical Engineering." Includes bibliographical references (p. 113-118).
120	Characterization of a monoclonal antibody reactive against major histocompatibility complex class II antigens / Yip, Tak-chun, Timothy. January 1992 (has links) Thesis (Ph. D.)--University of Hong Kong, 1993. / Cover title.

Search results