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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

The relation between the membrance potential and the ion content of smooth muscle cells

Casteels, R. January 1965 (has links)
Thesis--Louvain. / Summary in English, Dutch, and French. Includes bibliographical references.

Studies on the assembly and topography of proteins in the muscle myofibril

Turner, Robert Craig. January 1980 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1980. / Typescript. Vita. Description based on print version record. Includes bibliographical references.

Quantitative relationships of the myofibrillar proteins myosin, actin and the troponin subunits

Yates, Lawrence Davis. January 1982 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1982. / Typescript. Vita. Includes bibliographical references (leaves 61-67).

The electrically stimulated muscular response via surface electrodes

Yamamoto, Toshiyasu. January 1983 (has links)
Thesis (M.S.)--University of Wisconsin--Madison, 1983. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 59-68).

An investigation of low threshold motor units in the human tibialis anterior muscle

Harrison, Virginia Florence, January 1959 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1959. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 102-133).

Immunofluorescence studies of normal and hyperthyroxic chicken skeletal muscle using anti-myosins

Carpenter, Charles Edward. January 1984 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1984. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 94-101).

MLCK/actin interaction in the contracting A7r5 cell and vascular smooth muscle

Thatcher, Sean Eric. January 2007 (has links)
Theses (Ph. D.)--Marshall University, 2007. / Title from document title page. Includes abstract. Document formatted into pages: contains x, 102 pages including illustrations. Bibliographical references at the end of each chapter.

The efficacy of Traumeel® S in reducing delayed onset muscle soreness

Saunders, Claire Ann 09 June 2009 (has links)

The efficacy of sodium phosphate D6 in delaying the onset of muscle fatigue during short duration, high intensity exercise

Beukes, Stéfan 29 July 2009 (has links)

The Regulation of Telomerase Reverse Transcriptase (TERT) by CCAAT/Enhancer Binding Protein β (C/EBPβ) During Skeletal Muscle Differentiation

Slivitzky, Kira January 2017 (has links)
Our lab has identified the bZIP transcription factor CCAAT/Enhancer Binding Protein beta (C/EBPβ) as a negative regulator of myogenic differentiation. C/EBPβ is highly expressed in satellite cells and is downregulated during myogenic differentiation, a step that is critical for terminal differentiation, as ectopic C/EBPβ expression blocks this process. Telomerase has been identified as a C/EBPβ target gene in liver and other systems, and has been implicated in the regulation of muscle regenerative responses in models of Duchenne Muscular Dystrophy. Given that C/EBPβ is overexpressed in models of muscle wasting, and high levels of telomerase inhibit differentiation, I hypothesized that C/EBPβ inhibits myogenic differentiation through upregulation of TERT (telomerase reverse transcriptase) expression. I demonstrate that overexpression of C/EBPβ in myoblasts increases mTERT expression under both growth and differentiation conditions. Conversely, loss of C/EBPβ expression in myoblasts using shRNA technology or after isolation of primary myoblasts from conditional knockout mice, results in a downregulation of TERT expression and activity. When TERT was pharmacologically inhibited or knocked down using a shRNA, there was a significant improvement in differentiation and fusion in C2C12 myoblasts overexpressing C/EBPβ as evidenced by an increase in the number of MHC+ fibers and expression of muscle-specific differentiation genes. Interestingly, I found that C/EBPβ and TERT expression were increased in both embryonic and alveolar models of rhabdomyosarcoma. In response to this, a knockdown of C/EBPβ in rhabdomyosarcoma cells decreased TERT expression and activity, and enhanced differentiation but not fusion in a model of embryonic rhabdomyosarcoma. These findings illustrate the novel regulation of TERT in skeletal muscle by C/EBPβ, and reveal C/EBPβ as an attractive therapeutic target for the treatment of muscle diseases such as rhabdomyosarcoma.

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