Thesis (M.S.)--University of Michigan, 1958.

Thesis (M.S.)--University of Michigan, 1960.

Thesis (Ph. D.)--West Virginia University, 2007. / Title from document title page. Document formatted into pages; contains xii, 270 p. : ill. (some col.). Includes abstract. Includes bibliographical references.

In this experiment, fluorescent N- (1-pyrenyl) iodoacetamide modified the two reactive thiols, SH1 (Cys 707) and SH2 (Cys 697) on myosin to detect SH1-SH2 a -helix melting. The excimer forming property of pyrene is well suited to monitor the dynamics of the SH1 and SH2 helix melting, since the excimer should only form during the melted state. Decreased anisotropy of the excimer relative to the monomeric pyrene fluorescence is consistent with the disordering of the melted SH1-SH2 region in the atomic model. Furthermore, nucleotide analogs induced changes in the anisotropy of the excimer, suggesting that the nucleotide site modulates the flexibility of SH1-SH2 region.

published_or_final_version / Physiology / Master / Master of Philosophy

Although the neural mechanisms responsible for the orderly recruitment of motor units have been investigated extensively, the flexibility of the underlying neural circuitry remains unclear. For example, the effects of electrical stimulation on the recruitment order of motor units is not well understood. This project was designed to study the recruitment order of motor units in man during different stimulation protocols. Examination of the compound-twitch characteristics of electrically evoked responses allowed an indirect determination of motor-unit recruitment order. The results demonstrate that the recruitment order of quadriceps femoris and triceps surae motor units differs according to the stimulation protocols used. Analysis of the compound-twitch characteristics indicated that the recruitment order of motor units during Hoffmann reflexes is similar to that of volitional muscle contractions but effectively the reverse of that during direct-motor responses. Moreover, the results suggest that cutaneous-afferent stimulation alters the recruitment thresholds of different motor unit types during the Hoffman reflex.

No description available.

No description available.

Thesis (Ph. D.)--University of Texas at Austin, 2000. / Vita. Includes bibliographical references (leaves 119-126). Available also in a digital version from Dissertation Abstracts.

Thesis (M. Phil.)--University of Hong Kong, 1974. / Mimeographed.