This research examined the time-course of muscle damage in the squat, bench press, and deadlift. Ten resistance-trained males performed four sets to failure with 80% of one-repetition maximum (1RM) for each exercise on three separate weeks. Swelling, range of motion (ROM), delayed onset muscle soreness (DOMS), lactate dehydrogenase (LDH), creatine kinase (CK), and average concentric velocity (ACV) were assessed pretraining and at five timepoints post-training: -0, 24, 48, 72, and 96 hours. Swelling (p<0.01) increased immediately post-training, and DOMS (p<0.01) increased at 24 hours post-training in the bench press condition. Additionally, DOMS increased at 48 hours in both squat and deadlift conditions (p<0.01). Squat and deadlift elevated CK immediately post-training (p<0.01), but LDH only increased in the squat post-training. Immediately post in the bench press ACV was decreased (p<0.01) along with in the squat for up to 72 hours (p<0.01), however, ACV did not change following the deadlift (p>0.05). / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2018. / FAU Electronic Theses and Dissertations Collection