Thesis (M.S.)--Montana State University--Bozeman, 2006. / Typescript. Chairperson, Graduate Committee: Mark T. Quinn. Includes bibliographical references (leaves 78-94).

Thesis (Ph. D.)--Case Western Reserve University, 2007. / [School of Medicine] Department of Pathology. Includes bibliographical references. Available online via OhioLINK's ETD Center.

Thesis (Ph. D.)--University of Iowa, 2007. / Supervisors: Jerrold P. Weiss, William M. Nauseef. Includes bibliographical references (leaves 101-119).

No description available.

When, at the beginning of 1972, my scientific attention was first drawn to the subject of cellular participation in the inflanunatory response, I was struck by the need for an understanding of the cellular and molecular mechanisms whereby blood leucocytes are attracted to an area of injury. The literature at that time contained good technical accounts of methods available for studying chemotaxis in vitro and many reports of diverse compounds of biological origin with attractant, or chemotactic, properties for motile, phagocytic cells. In general, these reports tended to substantiate the belief that chemical substances generated at an inflannnatory source attracted cells to that source in a teleologically appropriate way and they justified, by the consistent correlation observed, the relevance of in vitro procedures for studying the phenomenon. In other words, answers were available to the question "What substances attract?"; very few were available to the question, "How do they attract?".

A Dissertation submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, for the Degree of Master of Science (MED). JOHANNESBURG, 1986 / The Literature Review covers the immunosuppressive and immunopotentiating properties of antibiotics on the immune system and the effects these could have on the resolution of an infection. The possible pathogenic mechanisms of C. albicans are also reviewed in this section. The experimental section shows that pre-treatment of mice with erythromycin increases the mean survival time following intraperitoneal inoculation of C. albicans. It was shown that erythromycin enhanced lymphocyte transformation and PMNL migration in both in-vivo and in-vitro situations. These enhanced immunological components probably caused improved survival times in the aforementioned animal experiments. To investigate the effects of oral administration of erythromycin on in-vivo PMNL migration in adult volunteers a new quantitative test which could only be applied to humans was developed and is described in detail. Using this method preliminary data were obtained which show that erythromycin increases PMNL migration in-vivo. / IT2018

This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).

This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).

No description available.

No description available.