Diese Dissertation geht um die Validation der deutschen Version des Fragebogen 'Mediterranean Diet Adherence Screener' (MEDAS) im Rahmen der LIBRE (Lebensstilintervention in Frauen mit einer BRCA1 oder BRCA2 Mutation) Studie.:Table of contents Bibliographical description.......................................................................................iii Background.............................................................................................................. 1 1.1. Lifestyle factors and risk of sporadic breast cancer.......................................... 2 1.2. Mediterranean Diet ........................................................................................... 3 1.3. Non-genetic risk factors for disease in BRCA1 and BRCA2 mutation carriers. 5 1.4. LIBRE trial.......................................................................................................... 6 1.5. Mediterranean Diet Adherence Screener questionnaire.................................... 7 1.5.1. Translation process........................................................................................ 9 1.6. Food Frequency Questionnaire ........................................................................ 9 Aim......................................................................................................................... 10 Publication ............................................................................................................. 11 Summary................................................................................................................ 21 References ............................................................................................................ 25 Abbreviations......................................................................................................... 33 Supplemental Materials ........................................................................................ 35 Statement on own contributions .......................................................................... 46 Erklärung über die eigenständige Abfassung der Arbeit ...................................... 47 Curriculum Vitae ................................................................................................... 49 Acknowledgements .............................................................................................. 53 / This dissertation concerns the validation of the German version of the Mediterranean Adherence Screener (MEDAS), in the context of the LIBRE (Lebensstilintervention in Frauen mit einer BRCA1 oder BRCA2) Mutation clinical trial.:Table of contents Bibliographical description.......................................................................................iii Background.............................................................................................................. 1 1.1. Lifestyle factors and risk of sporadic breast cancer.......................................... 2 1.2. Mediterranean Diet ........................................................................................... 3 1.3. Non-genetic risk factors for disease in BRCA1 and BRCA2 mutation carriers. 5 1.4. LIBRE trial.......................................................................................................... 6 1.5. Mediterranean Diet Adherence Screener questionnaire.................................... 7 1.5.1. Translation process........................................................................................ 9 1.6. Food Frequency Questionnaire ........................................................................ 9 Aim......................................................................................................................... 10 Publication ............................................................................................................. 11 Summary................................................................................................................ 21 References ............................................................................................................ 25 Abbreviations......................................................................................................... 33 Supplemental Materials ........................................................................................ 35 Statement on own contributions .......................................................................... 46 Erklärung über die eigenständige Abfassung der Arbeit ...................................... 47 Curriculum Vitae ................................................................................................... 49 Acknowledgements .............................................................................................. 53