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It is essential for surgeons to have their skill evaluated prior to entering the oper- ating room. Most evaluation methods currently in use are subjective, relying on human judgment to assess trainees. Recently, sensors have been used to track the positions of instruments and the forces applied to them by surgeons, opening up the possibility of automated skill analysis. This thesis presents a newly developed recording system, and novel methods used to automatically analyze surgical skill within the context of laparoscopic procedures. The evaluation methods are tested using an empirical study involving a number of participants with a wide range of surgical skill.

<p>An essential tool in the truck development process is the ability to quantify and grade vehicle dynamic behavior. Today this is performed either through subjective or objective tests. Subjective tests have the disadvantage that numerous factors influence test drivers’ opinions while objective measures have the advantage of repeatability. However, objective methods of today are often only able to provide a rough grading of vehicles. The main objective with this thesis is to develop more sensitive objective methods for ride comfort evaluation.</p><p>An effective test procedure to measure driver perception sensitivity to small differences in vehicle ride is suggested and utilized. The driver sensitivity is tested on dynamic behavior that is typically graded in vehicle development. Cab motions from a truck are first measured and then recreated in a simulator where a test driver is seated. The perception threshold for small changes in typical vehicle motion is established in this way for each test person.</p><p>The perception sensitivity tests indicate that humans are quite sensitive to transients in vehicle motion. One problem with many common vehicle ride measures is that the impact of transient behavior is small due to the averaging used to condense the measurement data into scalar measures. A new evaluation method for ride comfort, with influences from the well known handling diagram, is suggested. This method has four main advantages: it is fairly simple to interpret, it shows the absolute vibration level, it considers transient events separately and it shows changes in vehicle character with increasing excitation. Promising results from both measurements and simulations are derived.</p><p>New technology has made it possible to vary vehicle suspension parameters during vehicle ride. In order to prescribe different damping for different vehicle modes, modal motion estimates are needed. A system identification approach is suggested. It yields improved estimates of vehicle modal motion compared to previous work.</p>

An essential tool in the truck development process is the ability to quantify and grade vehicle dynamic behavior. Today this is performed either through subjective or objective tests. Subjective tests have the disadvantage that numerous factors influence test drivers’ opinions while objective measures have the advantage of repeatability. However, objective methods of today are often only able to provide a rough grading of vehicles. The main objective with this thesis is to develop more sensitive objective methods for ride comfort evaluation. An effective test procedure to measure driver perception sensitivity to small differences in vehicle ride is suggested and utilized. The driver sensitivity is tested on dynamic behavior that is typically graded in vehicle development. Cab motions from a truck are first measured and then recreated in a simulator where a test driver is seated. The perception threshold for small changes in typical vehicle motion is established in this way for each test person. The perception sensitivity tests indicate that humans are quite sensitive to transients in vehicle motion. One problem with many common vehicle ride measures is that the impact of transient behavior is small due to the averaging used to condense the measurement data into scalar measures. A new evaluation method for ride comfort, with influences from the well known handling diagram, is suggested. This method has four main advantages: it is fairly simple to interpret, it shows the absolute vibration level, it considers transient events separately and it shows changes in vehicle character with increasing excitation. Promising results from both measurements and simulations are derived. New technology has made it possible to vary vehicle suspension parameters during vehicle ride. In order to prescribe different damping for different vehicle modes, modal motion estimates are needed. A system identification approach is suggested. It yields improved estimates of vehicle modal motion compared to previous work. / QC 20101221

The aim of our study was to assess the changes of free radicals and other biochemical parameters after nociceptive stimulation in different experimental animal models. In patiens we detected whether preemptive analgesia had a positive effect on acute postoperative pain. Objective evaluation of pain intensity is a long-term problem because the objectification of using electrophysiological and imaging methods is currently difficult and expensive, and therefore in laboratories in the Czech Republic and many other places are used the evaluation by means biochemical methods. We implemented large experimental studies using mechanical, inflammatory and visceral nociception and we found out in particular that nitroxid and hydroxyl free radicals and singlet oxygen increased significantly after nociceptive stimulation. This increase can be suppressed by antioxidants. At the same time, we showed that some parameters of metabolism lipids, carbohydrates and proteins have also been changed. In particular, we measured the free hydroxyl radicals and singlet oxygen by EPR method in the tail of living and anesthetized rats. This method is absolutely a priority and has never been used before. Earlier experimental results were partially clinically verified using different types of acute and chronic pain in humans...

brace on the child's motor development and it briefly informs about the possibilities of the objective evaluation of child' significant influence of the diagnosis DDH and inseparable orthopaedic brace on the child's - ltaneusly intensive physiotherapy using Vojta's reflex

[pt] As técnicas de estimação de movimento utilizadas nos padrões de compressão de vídeo proporcionam a utilização mais eficiente dos recursos de transmissão e armazenamento, através da redução do número de bits necessários para representar um sinal de vídeo e da conservação da qualidade do conteúdo que está sendo processado. O objetivo dessa dissertação de Mestrado é propor um novo algoritmo capaz de reduzir a grande complexidade computacional envolvida nestas técnicas, mantendo a qualidade do sinal reconstruído. Dessa maneira, apresenta-se um algoritmo AUMHS (Adaptive Unsymmetrical-cross Multi-Hexagon-grid Search) o qual traz como principais modificações ao algoritmo UMHS (Unsymmetrical-cross Multi-Hexagon-grid Search) a implementação de uma medida de movimento que classifica as cenas de uma seqüência de vídeo de acordo com o movimento detectado para posterior adequação dos parâmetros de estimação de movimento e de outros parâmetros do codificador. Como resultado apresenta-se um ganho expressivo na velocidade de processamento, e conseqüente redução do custo computacional, conservando-se a qualidade obtida pelos principais algoritmos da literatura. O algoritmo foi implementado no codificador do padrão H.264/AVC onde realizou-se análises comparativas de desempenho com os algoritmos UMHS e FSA através da medição de parâmetros como PSNR (Peak Signal to Noise Ratio), tempo de processamento do codificador, tempo de processamento do módulo de estimação de movimento, taxa de bits utilizada e avaliação subjetiva informal. / [en] The motion estimation techniques used by the video compression standards provide an efficient utilization of the transmission and storage resources, through the reduction of the number of bits required to represent a video signal and the conservation of the content quality that is being processed. The objective of this work is to propose a new algorithm capable of reducing the great computational complexity involved in the motion estimation techniques, keeping the quality of the reconstructed signal. In this way, we present an algorithm called AUMHS (Adaptive Unsymmetrical-cross Multi-Hexagon-grid Search) which brings as main modifications relative to the UMHS (Unsymmetrical-cross Multi-Hexagon-grid Search) the implementation of a movement measure that can classify the scenes of a video sequence according to the motion detected for posterior adequacy of the motion estimation and others coder parameters. As result we present an expressive gain in the processing speed, and consequent computational cost reduction, conserving the same quality of the main algorithms published in the literature. The algorithm was implemented in the H.264/AVC coder in order to proceed with comparative analysis of perfomance together with the UMHS and FSA algorithms, measuring parameters as PSNR (Peak Signal you the Noise Ratio), coding processing time, motion estimation time, bit rate, and informal subjective evaluation.

Doctor of Philosophy / Radiographic film/screen (F/S) images have a narrow latitude or dynamic range. The film’s ability to record and view all the anatomy within the x-ray field is limited by this narrow dynamic range. The advent of digital radiographic means of storing and displaying radiographic images has improved the ability to record and visualise all of the anatomy. The problem still exists in digital radiography (DR) when radiographic examinations of certain anatomical regions are undertaken. In this work, the value of anatomically shaped radiographic contrast-enhancement masks (RCMs) in improving image contrast and reducing the dynamic range of images in DR was examined. Radiographic contrast-enhancement masks are digital masks that alter the radiographic contrast in DR images. The shape of these masks can be altered by the user. Anatomically shaped RCMs have been modelled on tissue compensation filters (TCFs) commonly used in F/S radiographic examinations. The prime purpose of a TCF is to reduce the dynamic range of photons reaching the image receptor and hence improve radiographic contrast in the resultant image. RCMs affect the dynamic range of the image rather than the energy source of the image, that of the x-ray photons. The research consisted of three distinct phases. The first phase was to examine physical TCFs and their effects on F/S radiographic images. Physical TCFs are used in radiographic F/S examinations to attenuate the x-ray beam to compensate for varying patient tissue thicknesses and/or densities. The effect of the TCF is to reduce resultant radiographic optical density variations in the image, allowing the viewer to observe a range of densities within the image which would otherwise not be visualised. Physical TCFs are commonly aluminium- or lead-based materials that attenuate the x-ray beam. A TCF has varying physical thickness to differentially attenuate the iii beam and is shaped for specific anatomical situations. During this project, various commonly used physical TCFs were examined. Measurements of size and thickness were made. Characteristics of linear attenuation coefficients and half-value thicknesses were delineated for various TCF materials and at various energies. The second phase of the research was to model the physical TCFs in a digital environment and apply the RCMs to DR images. The digital RCMs were created with similar characteristics to mimic the shapes to the physical TCFs. The RCM characteristics can be adjusted by the viewer of the image to suit the anatomy being imaged. Anatomically shaped RCMs were designed to assist in overcoming a limitation when viewing digital radiographic images, that of the dynamic range of the image. Anatomically shaped RCMs differ from other means of controlling the dynamic range of a digital radiographic image. It has been shown that RCMs can reduce the range of optical densities within images with a large dynamic range, to facilitate visualisation of all anatomy within the image. Physical TCFs are used within a specific range of radiographic F/S examinations. Digital radiographic images from this range of examinations were collected from various clinical radiological centres. Anatomically shaped RCMs were applied to the images to improve radiographic contrast of the images. The third phase of the research was to ascertain the benefits of the use of RCMs. Various other methods are currently in use to reduce the dynamic range of digital radiographic images. It is generally accepted that these methods also introduce noise into the image and hence reduce image quality. Quantitative comparisons of noise within the image were undertaken. The anatomically shaped RCMs introduced less noise than current methods designed to reduce the dynamic range of digital radiographic images. It was shown that RCM methods do not affect image quality. Radiographers make subjective assessment of digital radiographic image quality as part of their professional practice. To assess the subjective quality of images enhanced with anatomically shaped RCMs, a survey of radiographers and other iv qualified people was undertaken to ascertain any improvement in RCM-modified images compared to the original images. Participants were provided with eight pairs of image to compare. Questions were asked in the survey as to which image had the better range of optical densities; in which image the anatomy was easiest to visualise; which image had the simplest contrast and density manipulation for optimal visualisation; and which image had the overall highest image quality. Responses from 123 participants were received and analysed. The statistical analysis showed a higher preference by radiographers for the digital radiographic images in which the RCMs had been applied. Comparisons were made between anatomical regions and between patient-related factors of size, age and whether pathology was present in the image or not. The conclusion was drawn that digital RCMs correctly applied to digital radiographic images decrease the dynamic range of the image, allowing the entire anatomy to be visualised in one image. Radiographic contrast in the image can be maximised whilst maintaining image quality. Using RCMs in some digital radiographic examinations, radiographers will be able to present optimised images to referring clinicians. It is envisaged that correctly applied RCMs in certain radiographic examinations will enhance radiographic image quality and possibly lead to improved diagnosis from these images.

Doctor of Philosophy / Radiographic film/screen (F/S) images have a narrow latitude or dynamic range. The film’s ability to record and view all the anatomy within the x-ray field is limited by this narrow dynamic range. The advent of digital radiographic means of storing and displaying radiographic images has improved the ability to record and visualise all of the anatomy. The problem still exists in digital radiography (DR) when radiographic examinations of certain anatomical regions are undertaken. In this work, the value of anatomically shaped radiographic contrast-enhancement masks (RCMs) in improving image contrast and reducing the dynamic range of images in DR was examined. Radiographic contrast-enhancement masks are digital masks that alter the radiographic contrast in DR images. The shape of these masks can be altered by the user. Anatomically shaped RCMs have been modelled on tissue compensation filters (TCFs) commonly used in F/S radiographic examinations. The prime purpose of a TCF is to reduce the dynamic range of photons reaching the image receptor and hence improve radiographic contrast in the resultant image. RCMs affect the dynamic range of the image rather than the energy source of the image, that of the x-ray photons. The research consisted of three distinct phases. The first phase was to examine physical TCFs and their effects on F/S radiographic images. Physical TCFs are used in radiographic F/S examinations to attenuate the x-ray beam to compensate for varying patient tissue thicknesses and/or densities. The effect of the TCF is to reduce resultant radiographic optical density variations in the image, allowing the viewer to observe a range of densities within the image which would otherwise not be visualised. Physical TCFs are commonly aluminium- or lead-based materials that attenuate the x-ray beam. A TCF has varying physical thickness to differentially attenuate the iii beam and is shaped for specific anatomical situations. During this project, various commonly used physical TCFs were examined. Measurements of size and thickness were made. Characteristics of linear attenuation coefficients and half-value thicknesses were delineated for various TCF materials and at various energies. The second phase of the research was to model the physical TCFs in a digital environment and apply the RCMs to DR images. The digital RCMs were created with similar characteristics to mimic the shapes to the physical TCFs. The RCM characteristics can be adjusted by the viewer of the image to suit the anatomy being imaged. Anatomically shaped RCMs were designed to assist in overcoming a limitation when viewing digital radiographic images, that of the dynamic range of the image. Anatomically shaped RCMs differ from other means of controlling the dynamic range of a digital radiographic image. It has been shown that RCMs can reduce the range of optical densities within images with a large dynamic range, to facilitate visualisation of all anatomy within the image. Physical TCFs are used within a specific range of radiographic F/S examinations. Digital radiographic images from this range of examinations were collected from various clinical radiological centres. Anatomically shaped RCMs were applied to the images to improve radiographic contrast of the images. The third phase of the research was to ascertain the benefits of the use of RCMs. Various other methods are currently in use to reduce the dynamic range of digital radiographic images. It is generally accepted that these methods also introduce noise into the image and hence reduce image quality. Quantitative comparisons of noise within the image were undertaken. The anatomically shaped RCMs introduced less noise than current methods designed to reduce the dynamic range of digital radiographic images. It was shown that RCM methods do not affect image quality. Radiographers make subjective assessment of digital radiographic image quality as part of their professional practice. To assess the subjective quality of images enhanced with anatomically shaped RCMs, a survey of radiographers and other iv qualified people was undertaken to ascertain any improvement in RCM-modified images compared to the original images. Participants were provided with eight pairs of image to compare. Questions were asked in the survey as to which image had the better range of optical densities; in which image the anatomy was easiest to visualise; which image had the simplest contrast and density manipulation for optimal visualisation; and which image had the overall highest image quality. Responses from 123 participants were received and analysed. The statistical analysis showed a higher preference by radiographers for the digital radiographic images in which the RCMs had been applied. Comparisons were made between anatomical regions and between patient-related factors of size, age and whether pathology was present in the image or not. The conclusion was drawn that digital RCMs correctly applied to digital radiographic images decrease the dynamic range of the image, allowing the entire anatomy to be visualised in one image. Radiographic contrast in the image can be maximised whilst maintaining image quality. Using RCMs in some digital radiographic examinations, radiographers will be able to present optimised images to referring clinicians. It is envisaged that correctly applied RCMs in certain radiographic examinations will enhance radiographic image quality and possibly lead to improved diagnosis from these images.

Grafomotorické dovednosti (GA) představují skupinu psychomotorických procesů, které se zapojují během kreslení a psaní. GA jsou nutnou prerekvizitou pro zvládání základních školních schopností, konkrétně psaní. Děti v první a druhé třídě mohou mít potíže s prováděním jednoduchých grafomotorických úkolů (GD) a později ve třetí a čtvrté třídě také se samotným psaním (HD). Narušení procesů spojených se psaním je obecně nazýváno jako vývojová dysgrafie (DD). Prevalence DD v České republice se pohybuje kolem 3–5 %. V současné době je DD hodnocena subjektivně týmem psychologů a speciálních pedagogů. V praxi stále chybí objektivní měřicí nástroj, který by umožňoval hodnocení GD a HD. Z tohoto důvodu se tato disertační práce zabývá identifikováním symptomů spojených s grafomotorickou neobratností u dětí školního věku a vývojem nových parametrů, které je budou kvantifikovat. Byl vytvořen komplexní GA protokol (36 úloh), který představuje prostředí, ve kterém se mohou projevit různé symptomy spojené s GD a HD. K těmto symptomům bylo přiřazeno 76 kvantifikujících parametrů. Dále byla navrhnuta nová škála grafomotorických obtíží (GDRS) založena na automatizovaném zpracování online píma. Nakonec byla prezentována a otestována nová sada parametrizačních technik založených na Tunable Q Factor Wavelet Transform (TQWT). Parametry TQWT dokážou kvantifikovat grafomotorickou obratnost nebo nedostatečný projev v jemné motorice. GDRS přestavuje nový, moderní a objektivní měřící nástroj, který doposud chyběl jak v České republice, tak v zahraničí. Použití škály by pomohlo modernizovat jak diagnostiku DD, tak reedukační/remediační proces. Další výzkum by tento nástroj mohl adaptovat i do jiných jazyků. Navíc, tato metodologie může být použita a optimalizována pro diagnostiku dalších nemocí a poruch, které ovlivňují grafomotorické dovednosti, například pro autismus, poruchu pozornosti s hyperaktivitou (ADHD) nebo dyspraxii (DCD).