Yes / Computer aided geometric design is an area where the improvement of surface generation techniques is an everlasting demand since faster and more accurate geometric models are required. Traditional methods for generating surfaces were initially mainly based upon interpolation algorithms. Recently, partial differential equations (PDE) were introduced as a valuable tool for geometric modelling since they offer a number of features from which these areas can benefit. This work summarises the uses given to PDE surfaces as a surface generation technique together

Pharmaceutical tablets have been the most dominant form for drug delivery and they need to be strong enough to withstand external stresses due to packaging and loading conditions before use. The strength of the produced tablets, which is characterised by their compressibility and compactibility, is usually deter-mined through a physical prototype. This process is sometimes quite expensive and time consuming. Therefore, simulating this process before hand can over-come this problem. A technique for shape modelling of pharmaceutical tablets based on the use of Partial Differential Equations is presented in this thesis. The volume and the sur-face area of the generated parametric tablet in various shapes have been es-timated numerically. This work also presents an extended formulation of the PDE method to a higher dimensional space by increasing the number of pa-rameters responsible for describing the surface in order to generate a solid tab-let. The shape and size of the generated solid tablets can be changed by ex-ploiting the analytic expressions relating the coefficients associated with the PDE method. The solution of the axisymmetric boundary value problem for a finite cylinder subject to a uniform axial load has been utilised in order to model a displace-ment component of a compressed PDE-based representation of a flat-faced round tablet. The simulation results, which are analysed using the Heckel model, show that the developed model is capable of predicting the compressibility of pharmaceutical powders since it fits the experimental data accurately. The opti-mal design of pharmaceutical tablets with particular volume and maximum strength has been obtained using an automatic design optimisation which is performed by combining the PDE method and a standard method for numerical optimisation.

No / Pharmaceutical tablets have been the most dominant form for drug delivery and most of them are used in the oral administration of drugs. These tablets need to be strong enough so that they can tolerate external stresses. Hence, during the design process, it is important to produce tablets with maximum mechanical strength while conserving the properties of powder form components. The mechanical properties of these tablets are assessed by measuring the tensile strength, which is commonly measured using diametrical or axial compression tests. This work describes the parametric design and optimisation of solid pharmaceutical tablets in cylindrical and spherical shapes, which are obtained using a formulation based on the use of Partial Differential Equations (PDEs) for shape design. The PDE-based formulation is capable of parameterised complex shapes using the information from some boundary curves that describe the shape. It is shown that the optimal design of pharmaceutical tablets with a particular volume and maximum strength can be obtained using an automatic design optimisation which is performed by combining the PDE method and a standard method for numerical optimisation.

no / In this paper, we extend the use of the partial differential equation (PDE) method to head visualization with computed tomography (CT) data and show how the two primary medical visualization means, surface reconstruction, and volume rendering can be integrated into one single framework through PDEs. Our scheme first performs head segmentation from CT slices using a variational approach, the output of which can be readily used for extraction of a small set of PDE boundary conditions. With the extracted boundary conditions, head surface reconstruction is then executed. Because only a few slices are used, our method can perform head surface reconstruction more efficiently in both computational time and storage cost than the widely used marching cubes algorithm. By elaborately introducing a third parameter w to the PDE method, a solid head can be created, based on which the head volume is subsequently rendered with 3D texture mapping. Instead of designing a transfer function, we associate the alpha value of texels of the 3D texture with the PDE parameter w through a linear transform. This association enables the production of a visually translucent head volume. The experimental results demonstrate the feasibility of the developed head visualization method.

No / Parameterisation of facial expressions on PDE surface representations of human faces are presented in this work. Taking advantage of the boundary-value approach inherent to Bloor-Wilson PDE method, facial expressions are achieved by manipulating the original boundary curves. Such curves are responsible for generating a surface representation of a human face in its neutral configuration, so that regions on these curves represent a given facial expression in a fast and realistic manner. Additionally, the parameterisation proposed here is carried out by applying different mathematical transformations to the affected curves according to the corresponding facial expression. Full analytic expressions parameterising some of the most common facial expressions such as smiling and eyebrow raising are in this work. Some graphical examples of these facial expressions are used to illustrate the results obtained using Bloor-Wilson PDE method as the foundations of the parameterisation scheme proposed here. Thus, it is shown that an efficient, intuitive and realistic parameterisation of facial expressions is attainable using Bloor-Wilson PDE method in along with a suitable mathematical expression.

Pharmaceutical tablets have been the most dominant form for drug delivery and they need to be strong enough to withstand external stresses due to packaging and loading conditions before use. The strength of the produced tablets, which is characterised by their compressibility and compactibility, is usually deter-mined through a physical prototype. This process is sometimes quite expensive and time consuming. Therefore, simulating this process before hand can over-come this problem. A technique for shape modelling of pharmaceutical tablets based on the use of Partial Differential Equations is presented in this thesis. The volume and the sur-face area of the generated parametric tablet in various shapes have been es-timated numerically. This work also presents an extended formulation of the PDE method to a higher dimensional space by increasing the number of pa-rameters responsible for describing the surface in order to generate a solid tab-let. The shape and size of the generated solid tablets can be changed by ex-ploiting the analytic expressions relating the coefficients associated with the PDE method. The solution of the axisymmetric boundary value problem for a finite cylinder subject to a uniform axial load has been utilised in order to model a displace-ment component of a compressed PDE-based representation of a flat-faced round tablet. The simulation results, which are analysed using the Heckel model, show that the developed model is capable of predicting the compressibility of pharmaceutical powders since it fits the experimental data accurately. The opti-mal design of pharmaceutical tablets with particular volume and maximum strength has been obtained using an automatic design optimisation which is performed by combining the PDE method and a standard method for numerical optimisation.

This thesis discusses a novel method for modelling facial action units. It presents facial action units model based on boundary value problems for accurate representation of human facial expression in three-dimensions. In particular, a solution to a fourth order elliptic Partial Differential Equation (PDE) subject to suitable boundary conditions is utilized, where the chosen boundary curves are based on muscles movement defined by Facial Action Coding System (FACS). This study involved three stages: modelling faces, manipulating faces and application to simple facial animation. In the first stage, PDE method is used in modelling and generating a smooth 3D face. The PDE formulation using small sets of parameters contributes to the efficiency of human face representation. In the manipulation stage, a generic PDE face of neutral expression is manipulated to a face with expression using PDE descriptors that uniquely represents an action unit. A combination of the PDE descriptor results in a generic PDE face having an expression, which successfully modelled four basic expressions: happy, sad, fear and disgust. An example of application is given using simple animation technique called blendshapes. This technique uses generic PDE face in animating basic expressions.

Yes / In this work we propose a talking head system for animating facial expressions using a template face generated from Partial Differen- tial Equations (PDEs). It uses a set of preconfigured curves to calculate an internal template surface face. This surface is then used to associate various facial features with a given 3D face object. Motion retargeting is then used to transfer the deformations in these areas from the template to the target object. The procedure is continued until all the expressions in the database are calculated and transferred to the target 3D human face object. Additionally the system interacts with the user using an artificial intelligence (AI) chatterbot to generate response from a given text. Speech and facial animation are synchronized using the Microsoft Speech API, where the response from the AI bot is converted to speech.

This thesis discusses a novel method for modelling facial action units. It presents facial action units model based on boundary value problems for accurate representation of human facial expression in three-dimensions. In particular, a solution to a fourth order elliptic Partial Differential Equation (PDE) subject to suitable boundary conditions is utilized, where the chosen boundary curves are based on muscles movement defined by Facial Action Coding System (FACS). This study involved three stages: modelling faces, manipulating faces and application to simple facial animation. In the first stage, PDE method is used in modelling and generating a smooth 3D face. The PDE formulation using small sets of parameters contributes to the efficiency of human face representation. In the manipulation stage, a generic PDE face of neutral expression is manipulated to a face with expression using PDE descriptors that uniquely represents an action unit. A combination of the PDE descriptor results in a generic PDE face having an expression, which successfully modelled four basic expressions: happy, sad, fear and disgust. An example of application is given using simple animation technique called blendshapes. This technique uses generic PDE face in animating basic expressions. / Ministry of Higher Education, Malaysia and Universiti Malaysia Terengganu

Yes