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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

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Spelling suggestions: "subject:"paper spray dionization"" "subject:"paper spray d'ionization""

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Paper Spray - Mass Spectrometry: Investigation of Sampling Devices for Illicit Drug Detection and Quantification

Chau Bao Nguyen (11178123) 06 August 2021 (has links)
Different sampling devices for paper spray - mass spectrometry (PS - MS) were investigated to improve the assay’s simplicity and sensitivity over traditional approaches. In the first one, pressure-sensitive adhesive paper was used as both sampling tool to collect drug residues on surfaces and paper substrate in PS - MS analysis. This method showed a significant improvement in drug collection on surfaces leading to low nano-gram level detection limits. Other sampling device being investigated was snap-in solid-phase extraction column, which demonstrated the ability to detect trace amounts of drugs in plasma while allowed easy transportation and the use of PS - MS automated system.
Forensic Chemistry
Drug detection
Drug Quantification
paper spray mass spectrometry
Paper Spray Ionization
Pressure-sensitive adhesive
Drug Residues
Surface Sampling
Snap-in Solid-Phase Extraction Column
PS - MS
Sampling devices
PSA

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