Three-dimensional short-crested waves in Lagrangian form was already solved by Wang(2007). By employing the technique of perturbation analysis, the solution for the entire wave filed was obtained and the results are verified to be correct to second-order. The period of the trajectory of fluid particle in short-crested wave field was manifested in Lagrangian form. Consequently, all the characteristics of the flow field can be vividly described including the moving trajectory of fluid particle. To distinguish two different ways that short-crested waves might take place, Wang(2007)¡¦s results were extended to perturbation¡¦s third-order. The mechanism of resonance phenomenon is then clearly explained. In this study, the analytical results for the three-dimensional short-crested wave field correct to third-order were explicitly derived. The fluid particle with different initial positions or different phases has different moving trajectories. Besides, the period of the trajectory of fluid particle varies with different water depths. These are obviously revealed in our perturbation solutions. The three-dimensional short-crested wave system is successfully verified by reducing to two special cases, two-dimensional progressive waves and standing waves. Also, the analytical results were compared with experimental data including the surface profiles, the pressures, and the paths of fluid particles for validation. Furthermore, the mechanism of resonance phenomenon and the property of angular frequency were explained. Thus, the exactness and generality of the results are firm certified.

An optimal ordering scheme for the capacitated, finite-horizon, multi-period, multiproduct newsvendor problem was proposed by cite {shao06} using a hedging point policy. This solution requires the calculation of a central curve that divides the different ordering regions and a vector that defines the target inventory levels. The central curve is a nonlinear curve that determines the optimal order quantities as a function of the initial inventory levels. In this paper we propose a method for calculating this curve and vector using spline functions, infinitesimal perturbation analysis (IPA), and convex optimization. Using IPA the derivatives of the cost with respect to the variables that determine the spline function are efficiently calculated. A convex optimization algorithm is used to optimize the spline function, resulting in a optimal policy. We present the mathematical derivations and simulation results validating this solution.

<p>In perifusion cell cultures, the culture medium flows continuously through a chamber containing immobilized cells and the effluent is collected at the end. In our main applications, gonadotropin releasing hormone (GnRH) or oxytocin is introduced into the chamber as the input. They stimulate the cells to secrete luteinizing hormone (LH), which is collected in the effluent. To relate the effluent LH concentration to the cellular processes producing it, we develop and analyze a mathematical model consisting of coupled partial differential equations describing the intracellular signaling and the movement of substances in the cell chamber. We analyze three different data sets and give cellular mechanisms that explain the data. Our model indicates that two negative feedback loops, one fast and one slow, are needed to explain the data and we give their biological bases. We demonstrate that different LH outcomes in oxytocin and GnRH stimulations might originate from different receptor dynamics. We analyze the model to understand the influence of parameters, like the rate of the medium flow or the fraction collection time, on the experimental outcomes. We investigate how the rate of binding and dissociation of the input hormone to and from its receptor influence its movement down the chamber. Finally, we formulate and analyze simpler models that allow us to predict the distortion of a square pulse due to hormone-receptor interactions and to estimate parameters using perifusion data. We show that in the limit of high binding and dissociation the square pulse moves as a diffusing Gaussian and in this limit the biological parameters can be estimated.</p> / Dissertation

En ce moment même, d'énormes quantités de données sont générées, collectées et analysées. Dans de nombreux cas, ces données sont échantillonnées sur des objets à la structure géométrique particulière. De tels objets apparaissent fréquemment dans notre vie quotidienne. Utiliser ce genre de données pour inférer la structure géométrique de tels objets est souvent ardue. Cette tâche est rendue plus difficile encore si les objets sous-jacents sont abstraits ou encore de grande dimension. Dans cette thèse, nous nous intéressons à deux problèmes concernant l'analyse géométrique de données. Dans un premier temps, nous nous penchons sur l'inférence de la métrique de structures filamentaires. En supposant que ces structures sont des espaces métriques proches d'un graphe métrique nous proposons une méthode, combinant les graphes de Reeb et l'algorithme Mapper, pour approximer la structure filamentaire via un graphe de Reeb. Notre méthode peut de plus être facilement implémentée et permet de visualiser simplement le résultat. Nous nous concentrons ensuite sur le problème de la comparaison de formes. Nous étudions un ensemble de méthodes récentes et prometteuses pour la comparaison de formes qui utilisent la notion de carte fonctionnelles. Nos résultats théoriques montrent que ces approches sont stables et peuvent être utilisées dans un contexte plus général que la comparaison de formes comme la comparaison de variétés Riemanniennes de grande dimension. Enfin, en nous basant sur notre analyse théorique, nous proposons une généralisation des cartes fonctionnelles aux nuages de points. Bien que cette généralisation ne bénéficie par des garanties théoriques, elle permet d'étendre le champ d'application des méthodes basées sur les cartes fonctionnelles. / Massive amounts of data are being generated, collected and processed all the time. A considerable portion of them are sampled from objects with geometric structures. Such objects can be tangible and ubiquitous in our daily life. Inferring the geometric information from such data, however, is not always an obvious task. Moreover, it’s not a rare case that the underlying objects are abstract and of high dimension, where the data inference is more challenging. This thesis studies two problems on geometric data analysis. The first one concerns metric reconstruction for filamentary structures. We in general consider a filamentary structure as a metric space being close to an underlying metric graph, which is not necessarily embedded in some Euclidean spaces. Particularly, by combining the Reeb graph and the Mapper algorithm, we propose a variant of the Reeb graph, which not only faithfully approximates the metric of the filamentary structure but also allows for efficient implementation and convenient visualization of the result. Then we focus on the problem of shape comparison. In this part, we study the stability properties of some recent and promising approaches for shape comparison, which are based on the notion of functional maps. Our results show that these approaches are stable in theory and potential for being used in more general setting such as comparing high-dimensional Riemannian manifolds. Lastly, we propose a pipeline for implementing the functional-maps-based frameworks under our stability analysis on unorganised point cloud data. Though our pipeline is experimental, it undoubtedly extends the range of applications of these frameworks.

No description available.

Eccentric lunar frozen orbits are analyzed in this study in relation to lunar navigation and communications missions, particularly the proposed Magnolia-1 mission. An overview of the Earth/Moon system, frozen orbits, and the Magnolia-1 mission is provided. A review of existing literature is presented, and potential limitations are discussed. Both preliminary and numerical perturbation analyses are presented, and a general set of perturbations for further analysis of high-altitude lunar orbits is identified. Analysis of potential orbits for the Magnolia-1 mission is performed through calculation of a maximum deviation metric and through visualization as a function of initial orbital elements. Trends are identified within a closed search space by varying elements individually and in combination. Potential orbit designs for the Magnolia-1 mission are selected and compared to established alternatives. A method of orbit refinement is used to improve behavior, and coverage and eclipse analyses are performed to establish suitability. Conclusions are made involving general trends related to eccentric lunar frozen orbits and the specific designs proposed for the Magnolia-1 mission, and a method for the design of similar orbits is suggested. Ideas for further study are also presented.

No description available.

No description available.

Rotordynamic and thermal analyses of compliant flexure pivot tilting pad gas bearings were performed. First, compliant flexure pivot tilting pad gas bearings with pad radial compliance (CFTPBs) were introduced and designed for high-speed oil-free micro turbomachinery. The pad radial compliance was for accommodation of large rotor growth at high speeds. Parametric studies on pivot offset, preload, and tilting stiffness were performed using non-linear orbit simulations and coast-down simulations for an optimum design. Second, coast-down tests for imbalance response and stability of typical rotor-bearing system with a rigid rotor and two CFTPBs designed from the above design studies were conducted over operating speeds up to 55 krpm. Prediction of synchronous rotordynamic responses was made in terms of critical speed for various imbalance modes by using a rotordynamic analysis software (XLTRC), combined with dynamic force coefficients from the perturbation analysis. For stability analyses, a generalized orbit simulation program was developed considering both the translational and angular rotor motions with two different bearings. Linear stability analyses for the conical vibration mode were also performed by using XLTRC and the perturbation analysis based on the Lund method. Predictions of whirl speed showed good agreement to the tests, but the estimated onset speed of instability appeared lower than the measured instability. Finally, a new thermo-hydrodynamic analysis model of a typical rotor-bearing system with CFTPBs was presented, accompanying linear perturbation analyses to investigate thermal effects on the rotordynamic performance. A numerical procedure was established for solving the generalized Reynolds equation, the 3-D energy equation, and the associated boundary conditions at the pad inlet flow and solid walls (rotor and pad) simultaneously. Parametric studies were conducted on nominal clearance and external load. Nominal clearance showed significant influence on temperature fields, and external load had uneven thermal effects among pads. Case studies with heat flux and temperature boundary conditions on the rotor end surface were performed to simulate various working conditions of the bearing. Large rotor thermal growth due to the high rotor temperature showed noticeable influence on rotordynamic performance by increasing direct stiffness and damping coefficients.

Rotordynamic and thermal analyses of compliant flexure pivot tilting pad gas bearings were performed. First, compliant flexure pivot tilting pad gas bearings with pad radial compliance (CFTPBs) were introduced and designed for high-speed oil-free micro turbomachinery. The pad radial compliance was for accommodation of large rotor growth at high speeds. Parametric studies on pivot offset, preload, and tilting stiffness were performed using non-linear orbit simulations and coast-down simulations for an optimum design. Second, coast-down tests for imbalance response and stability of typical rotor-bearing system with a rigid rotor and two CFTPBs designed from the above design studies were conducted over operating speeds up to 55 krpm. Prediction of synchronous rotordynamic responses was made in terms of critical speed for various imbalance modes by using a rotordynamic analysis software (XLTRC), combined with dynamic force coefficients from the perturbation analysis. For stability analyses, a generalized orbit simulation program was developed considering both the translational and angular rotor motions with two different bearings. Linear stability analyses for the conical vibration mode were also performed by using XLTRC and the perturbation analysis based on the Lund method. Predictions of whirl speed showed good agreement to the tests, but the estimated onset speed of instability appeared lower than the measured instability. Finally, a new thermo-hydrodynamic analysis model of a typical rotor-bearing system with CFTPBs was presented, accompanying linear perturbation analyses to investigate thermal effects on the rotordynamic performance. A numerical procedure was established for solving the generalized Reynolds equation, the 3-D energy equation, and the associated boundary conditions at the pad inlet flow and solid walls (rotor and pad) simultaneously. Parametric studies were conducted on nominal clearance and external load. Nominal clearance showed significant influence on temperature fields, and external load had uneven thermal effects among pads. Case studies with heat flux and temperature boundary conditions on the rotor end surface were performed to simulate various working conditions of the bearing. Large rotor thermal growth due to the high rotor temperature showed noticeable influence on rotordynamic performance by increasing direct stiffness and damping coefficients.