Kaohsiung city for the south Taiwan industry strategic place, the Siaogang area is a heavy industry stands in great numbers the area, the rendering plant, the steel plant, petrifies the factory, the incineration plant, the shipyard, the airport and so on, moreover also has transport means and so on the container truck, carriage vehicle, airplane, The air quality fraction defective occupies crown of the whole city. Kaohsiung important empty unclean control key of suspended particulate pollution, This research is for the purpose of discussing Physicochemical characteristic analysis of air suspended particles in the heavy industry peripheral area, understood in the heavy industry peripheral area air the suspended particles pollutant originates. Physicochemical characteristic analysis discussion atmosphere pollutants to influence Siaogang area. This research in May 2009 period picks each time continual sampling 24 hours to carry on each week twice sampling respectively, the East, West, South and North central area average in the Siaogang area 5 points, altogether gathers 20 samples. Another gathers motorcycle/automobile/diesel car/boiler/voltaic arc boiler/fritting furnace/road dusts different of samples, altogether 14 samples. This research uses air sampling instrument (GAST) carries on the sampling to air of the Siaogang area. Using the scanning type electron microscope (Scanning electron microscope, SEM) and instruments and so on XRD (X-ray Diffractometer, XRD) carry on the metallic element and the physicochemical characteristic analysis. The time can of because of the Siaogang area atmosphere in the suspended particulate matter origin type and the contribution quantity, relevance of in order to help control of air suspended particles in the heavy industry peripheral area pollutant and the source of pollution. This research the main of purpose this study by under construction in the air in the surrounding areas of heavy industry in the pollutants of sampling technology, and discussion of pollutants by the scene size distribution and inorganic salts, and so particulate surface characteristics and analysis for the structure and composition. This research also use a variety of discussion on the valuable instrument analysis to peripheral areas of heavy industry in the pollutants in air of surface and microstructure characteristics, the result of the above analysis, may further in-depth understanding of the heavy industries in peripheral areas of pollutants characteristics, also took granular than in the air pollutants and other kinds of granular pollutant emission sources and physicochemical characteristics of the apparent, discussion of heavy industry in peripheral areas of major sources of granular pollutants for source decrement measures. Future expected completion of roads, schools, residential, farmland, rivers the downwind side of the land of bare ground, farming, construction site River dust, straw, dead wood, rubber, PVC plastic, PE/PP plastics non-heavy industry surrounding area of micro photo, composition and organizational analysis, and than the judgment against a database of all particulate sources.

Une exposition aux nanoparticules (NP) de dioxyde de titane (TiO2) peut entraîner un remodelage matriciel, dans lequel la Matrix Metalloprotéase-1 (MMP-1) notamment pourrait jouer un rôle important. Pour vérifier cette hypothèse, nous avons 1/ mesuré l' expression de la MMP-1 sur des fibroblastes pulmonaires humains après exposition à des particules de TiO2 de différentes tailles, formes et variétés cristallines, ainsi qu' une NP de noir de carbone (NC), et 2/ administré des NP de TiO2 et de NC sur un modèle d‟emphysème pulmonaire induit par l' élastase chez le rat. Sur les fibroblastes pulmonaires humains, certaines NP de TiO2 induisent l' expression de la MMP-1 via l' interleukine-1β (IL-1β) et augmentent son activité. Les particules de TiO2 micrométriques induisent l' expression de la MMP-1 sans lien avec l' IL-1β et les NP de NC ne modulent pas l' expression de la MMP-1. L' exposition des rats aux NP de TiO2 n' entraîne pas d' effet ; l' exposition aux NP de NC entraîne une inflammation et une induction de l' expression de la MMP-12. Cette exposition aggrave, de plus, l' inflammation provoquée par l' élastase, ce qui n' est pas observé avec les NP de TiO2. Au total, notre travail montre bien un rôle pour les NP de TiO2 dans le remodelage matriciel, via l' induction et l' activation de la MMP-1 in vitro. In vivo, les NP de NCpeuvent aggraver ceertaines réponses à l' élastse. La composition chimique et la taille des particules semblent être des déterminants importants de leurs effets. / Exposure to titanium dioxide (TiO2) nanoparticles (NP) can lead to matrix remodeling, a phenomenon in which Matrix metalloprotease-1 (MMP-1) notably could play an important role. To validate this hypothesis, we 1/ studied MMP-1 expression in human pulmonary fibroblasts after exposure to TiO2 particles of different sizes, shapes and crystal phases and one Carbon Black (CB) NP, and 2/ measured the effect of TiO2 CB NP on an elastase-induced emphysema model in rats.On human lung fibroblasts, some TiO2 NP induced MMP-1 through an interleukin-1β (IL-1β) dependent mechanism, and increased MMP-1 activity. TiO2 micrometric particles induced MMP-1 without IL-1β implication, and CB NP did not induce MMP-1. Rat exposure to TiO2 NP had no effect but exposure to NC NP induced inflammation and MMP-12 expression. TiO2 NP did not modulate elastase effects. NC NP aggravated elastase-induced inflammation.In total, our work shows a role for TiO2 NP in matrix remodeling, via MMP-1 induction and activation in vitro. In vivo, CB NP can aggravate some elastase-induced effects. Particles composition and size seem to be important determinants of their effect.